Hepatitis aguda recurrente inducida por albendazol / Recurrent albendazole-induced acute hepatitis
Narciso-Schiavon, Janaína Luz; Delziovo, Henrique Antonio; Benthien Santos, Lucas Eduardo; Cacese Shiozawa, Maria Beatriz; Lucca Schiavon, Leonardo.
Rev. colomb. gastroenterol
; 33(4): 473-477, oct.-dic. 2018. graf
Article
in Spanish
| LILACS | ID: biblio-985503
Abstract Albendazole is used to treat helminth infections and usually has minimal or no side effects. A transient increase in liver enzymes is common following its use, but little evidence of albendazole-induced liver damage has been reported in the literature. This study presents a patient who developed acute hepatitis following self-medication with albendazole. The patient also had a history of similar episodes in the past after using the drug. After a thorough investigation and exclusion of all other causes of the patient's clinical condition, the Roussel Uclaf Causality Assessment Method of the Council for International Organizations of Medical Sciences scale yielded a score of 10 points, indicating a high probability of albendazole-induced liver damage. In conclusion, expediting the process of combating helminths is ideal, but quality monitoring is required to avoid adverse reactions such as drug-induced hepatitis. Moreover, self-medication with any drug should always be discouraged.
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