Tratamento in vivo com M8, uma solução complexa altamente diluída, reduziu a malignidade de um modelo de melanoma de camundongo / In vivo treatment with M8, a highly diluted tinctures complex, reduced the malignancy of a mouse melanoma model
Andrade, Lucas Ferrari de; Guimarães, Fernando de Souza Fonseca; Rossi, Gustavo ; Zotz, Rafael ; Lozzo, Eneida J. Da; Franco, Célia Regina Cavichiolo; Oliveira, Carolina Camargo de ; Buchi, Dorly de Freitas; Trindade, Edvaldo da Silva .
Int. j. high dilution res
; 10(36): 142-144, september 30, 2011.
Article
in English
|
LILACS-Express
| ID: hom-10718
Background:
Cancer is a class of disease responsible for 13% of death cause worldwide. Among all types of cancers, one of the most aggressive and with the highest death rate is melanoma. It is highly metastatic and current treatments with chemotherapeutic drugs do not yield satisfactory results. Therefore, the interest on new therapeutics for cancer treatment has been increasing on research. Highly diluted tinctures (HDT) are intended to enhance immune system responses resulting in reduced frequency of various diseases, and often present no risk of serious side-effects due to its low toxicity. Previous results have demonstrated in vitro inhibition of invasion ability and in vivo anti-metastatic potential of B16F10 lung metastasis model after mice treatment with M8 inhalation.Conclusion:
Even though further investigation are necessary to elucidate the mechanisms of action of M8 treatment there is an indication that these highly diluted tinctures could be a promising therapy to treat metastatic melanoma.(AU)
Responsible library:
BR1.1
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