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Chronic toxicological effects of high diluted solutions of Aveloz (Euphorbia tirucalli L. ) on healthy mice: a preliminary study / Efeitos toxicológicos crônicos de altas diluições de Aveloz (Euphorbia tirucalli L. ) em camundongos sadios: estudo preliminar

Varricchio, Marcia CBN; Pereira, Cristiane; Sales, Fernanda; Gomes, Teresa; Daudt, Elaine; Aquino, Carolina Lessa; Barbosa, Gleyce Moreno; Nelson, Gomes; Pyrrho, Alexandre dos Santos; Hobaica, Paulo Eduardo Mansur; Branco, Morgana Castelo; Kuster, Ricardo; Holandino, Carla Holandino.
Int. j. high dilution res ; 7(25): 174-178, 2008. graf
Article in English | LILACS | ID: lil-529849
The latex extracted from Euphorbia tirucalli, a plant popularly known as Aveloz, is used in complementary medicine to induce tumor regression. However, as this latex has toxic effects when administered orally in ponderal doses, the present study was designed to assess the effects of high dilutions in healthy mice over a period of 18 weeks. The Aveloz latex-high diluted solutions (latex-HD) were obtained through the interaction of two processes 1100 dilution in mass and succussion, using ethanol 70% as a solvent, in the homeopathic dilutions of 5, 15 and 30cH, following Farmacopéia Homeopática Brasileira. Control solutions without latex were compounded (ethanolic-HD) in the same dilutions and were administered simultaneously. The animals which received latex-HD 30cH showed a significant increase in food consumption (p < 0.05) without significant difference in weight gain. In regards to water consumption, no statistical difference was shown when different Aveloz latex-HD groups were compared, apart from the group that received 1 drop of pure latex in water, which presented a significant increase (p < 0.05) in this parameter.
Responsible library: BR926.1
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