Effectiveness of an add-on treatment with the homeopathic medication SilAtro-5-90 in recurrent tonsillitis: An international, pragmatic, randomized, controlled clinical trial.
Complement Ther Clin Pract
; 28: 181-191, 2017 Aug.
Article
in En
| MEDLINE
| ID: mdl-28779928
ABSTRACT
OBJECTIVE:
To investigate the effectiveness and safety of the homeopathic product SilAtro-5-90 in recurrent tonsillitis.METHODS:
In this international, pragmatic, controlled clinical trial, 256 patients (6-60 years) with moderate recurrent tonsillitis were randomized to receive either SilAtro-5-90 in addition to standard symptomatic treatment, or to receive standard treatment only. The primary outcome was the mean time period between consecutive acute throat infections (ATI) within 1 year (analyzed via repeated events analysis).RESULTS:
During the evaluation year, the risk of getting an ATI was significantly lower (hazard ratio 0.45, proportional means model, p = 0.0002, ITT) with SilAtro-5-90 compared to control. Tonsillitis-specific symptoms were significantly reduced (p < 0.0001, ITT) and the need of antibiotics to treat acute throat infections (p = 0.0008; ITT) decreased. 3 non-serious adverse drug reactions were reported for SilAtro-5-90.CONCLUSIONS:
An integrative treatment approach where SilAtro-5-90 is given alongside mainstream symptomatic treatment may bring therapeutic benefit to patients suffering from recurrent tonsillitis. TRIAL REGISTRATION ISRCTN registry Registration number ISRCTN19016626, registered 23 January 2013.Key words
Full text:
1
Database:
MEDLINE
Main subject:
Materia Medica
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Tonsillitis
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Homeopathy
Type of study:
Clinical_trials
Limits:
Adolescent
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Adult
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Child
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Female
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Humans
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Male
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Middle aged
Language:
En
Journal:
Complement Ther Clin Pract
Year:
2017
Type:
Article