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Influência da idade e esquema de tratamento na parasitemia de camundongos infectados pelo Trypanosoma cruzi tratados com bioterápico de alta potência / Influence of age and ways of treatment in the parasitemia in mice infected with Trypanosoma cruzi treated with high potency biotherapy

Aleixo, Denise Lessa ; Braga, Caroline Felício; Moreira, Neide Martins ; Massini, Paula Fernanda; Brustolin, Camila Fernanda; Ferraz, Fabiana Nabarro; Araújo, Silvana Marques de.
Int. j. high dilution res ; 10(36): 138-141, september 30, 2011.
Artículo en Inglés | LILACS-Express | ID: hom-10719
ABSTRACT

Introduction:

The infection of mice by Trypanosoma cruzi is well known, making this a good model for understanding the effect of highly diluted medications. Mice of different ages show different responses to biotherapic T. cruzi [1]. Other data from our laboratory using biotherapic treatment at low potencies show that long lasting treatment has a better effect in mice infected with T. cruzi. However, the use of high potency biotherapics in mice of different ages infected with T. cruzi has not been analysed yet.

Conclusion:

The age and the ways of treatment used are important factors to be considered when using a highly diluted medication. The clinical use of these results in humans, should take into consideration the allometric system of medication dosage which takes into account the metabolic rate of each organism.(AU)
Biblioteca responsable: BR1.1
Selo DaSilva