From the homeopathic perspective, acne is not merely a disease to be healed, butcarries semiologic markers for both its treatment and to diagnose the constitutional(typological) medicine of the patient. This is the second of a series of articles devoted to analyze the individualizing characteristics of acne. For this purpose, visual semiology and analysis by means of classes of homeopathic medicines are used. Part II is devoted to homeopathic agent Hepar sulphur and its differential diagnosis relative to the sulfur class.