ABSTRACT
OBJECTIVE: To compare the efficacy and safety of the use of transcervical Foley's catheter versus Cook cervical ripening balloon in pregnant women with stillbirth, unfavorable cervix and scarred uterus. DESIGN: Randomized controlled study. SETTING: El Minia University Hospital, El Minia, Egypt. PATIENTS AND METHODS: Two-hundred pregnant women with stillbirth, unfavorable cervix and scarred uterus were recruited into this study. They were randomized into two groups. In group I (n = 100), cervical ripening was done using Foley's catheter. In group II (n = 100), cervical ripening was done using Cook cervical ripening balloon. MAIN OUTCOME MEASURES: Balloon insertion to delivery interval, successful ripening rate, cesarean delivery rate, maternal adverse events and maternal satisfaction. RESULTS: Time from balloon insertion to expulsion and from balloon insertion to delivery was significantly shorter in Foley's catheter group. However, the difference between the two groups regarding time from balloon insertion to active labor, time from balloon expulsion to delivery, cervical ripening, cesarean section, instrumental delivery, pain score, need for analgesia, hospital stay and maternal satisfaction was not statistically significant. CONCLUSIONS: Foley's catheter and Cook cervical ripening balloon are comparable regarding efficacy and safety profile when used to ripen the cervix in pregnant women with stillbirth, unfavorable cervix and scarred uterus. However, Foley's catheter has a shorter induction to delivery interval and is relatively cheaper device.
Subject(s)
Cervical Ripening , Cervix Uteri/pathology , Delivery, Obstetric/instrumentation , Stillbirth , Urinary Catheterization/methods , Uterus/pathology , Administration, Intravaginal , Adult , Cicatrix , Egypt , Female , Humans , Labor, Induced/methods , Obstetric Labor Complications , Pregnancy , Young AdultABSTRACT
Re-examination of the chemical constituents of the leaves of Ferula sinaica afforded a new eudesmanolide and a new carotane. The structures were elucidated by spectroscopic methods.
Subject(s)
Biological Factors/chemistry , Ferula/chemistry , Naphthalenes/chemistry , Naphthalenes/isolation & purification , Plants, Medicinal/chemistry , Plants, Toxic , Sesquiterpenes, Eudesmane , Sesquiterpenes , Biological Factors/isolation & purification , Egypt , Medicine, Traditional , Phytotherapy , Plant Leaves/chemistryABSTRACT
Full text is available as a scanned copy of the original print version.
Subject(s)
Neutrons , Radiometry , Spectrum Analysis , Beryllium , Nuclear Reactors , Plutonium , Radiation Dosage , Radiation Protection , Technology, RadiologicABSTRACT
Pityrosporum folliculitis (PF) is frequently misdiagnosed as acne vulgaris, resulting in unnecessary and prolonged treatment. Sixty-two patients with PF seen in the Dermatology Clinic, King Gahad Hofuf Hospital, Saudi Arabia were evaluated clinically. The diagnosis was confirmed by routine histology with haemotoxylineosin staining and Periodic acid-Schiff staining. Scrapings of the lesions, especially the molluscum-like papules, were mounted in KOH/Parker blue ink and examined under the microscope. Patients, divided into three groups as follows, were given treatment for 4 weeks: (1) 20 were treated with ketoconazole, 200 mg orally in addition to ketoconazole shampoo 2% daily; (2) 20 were given only ketoconazole, 200 mg daily, orally; (3) 12 used econazole nitrate 1% solution applied twice daily; and (4) 10 used miconazole nitrate 2% cream twice daily. Cases in groups 3 and 4, who did not respond, were given the same treatment as for group 1. All who responded were kept on ketoconazole shampoo 2% twice weekly. PF was commoner in young adult females as the female to male ratio was 2:1 while the mean age was 21.5 years. The most common site involved was the trunk (95%) in the form of papules, pustules and molluscoid lesions. The latter type of lesion yielded the highest number of spores using KOH/Parker blue ink. Biopsy was positive in 87% of the patients but is usually not necessary. Combined topical and systemic ketoconazole produced clearance of the lesions in 20 patients (100%), while systemic therapy only resulted in 75% clearance (15 of 20). Topical econazole and miconazole failed in 20 of 22 (90%) and improved only two patients. There were no significant side-effects from the drugs.