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1.
J Shoulder Elbow Surg ; 32(4): 695-702, 2023 Apr.
Article in English | MEDLINE | ID: mdl-36535559

ABSTRACT

BACKGROUND: Neer type IIB lateral clavicle fractures are inherently unstable fractures with associated disruption of the coracoclavicular (CC) ligaments. Because of the high rate of nonunion and malunion, surgical fixation is recommended; however, no consensus has been reached regarding the optimal fixation method. A new plating technique using a superior lateral locking plate with anteroposterior (AP) locking screws, resulting in orthogonal fixation in the lateral fragment, has been designed to enhance stability and reduce implant failure. The purpose of this study was to biomechanically compare 3 different clavicle plating constructs within a fresh frozen human cadaveric shoulder model. METHODS: Twenty-four fresh frozen cadaveric shoulders were randomized into 3 groups (n = 8 specimens): group 1, lateral locking plate only (Medartis Aptus Superior Lateral Plate); group 2, lateral locking plate with CC stabilization (No. 2 FiberWire); and group 3, lateral locking plate with 2 AP locking screws stabilizing the lateral fragment. All specimens were subject to cyclic loading of 70 N for 500 cycles. Data were analyzed for gap formation after cyclic loading, construct stiffness, and ultimate load to failure, defined by a marked decrease in the load displacement curve. RESULTS: After 500 cycles, there was no statistically significant difference between the 3 groups in gap formation (P = .179). No specimen (0/24) failed during cyclic loading. Ultimate load to failure was significantly higher in group 3 compared to group 1 (286 N vs. 167 N; P = .022), but not to group 2 (286 N vs. 246 N; P = .604). There were no statistically significant differences in stiffness (group 1: 504 N/mm; group 2: 564 N/mm; group 3: 512 N/mm; P = .712). Peri-implant fracture was the primary mode of failure for all 3 groups, with group 3 demonstrating the lowest rate of peri-implant fractures (group 1: 6/8; group 2: 7/8; group 3: 4/8; P = .243). CONCLUSION: Biomechanical evaluation of the clavicle plating techniques showed effective fixation across all specimens at 500 cycles. The lateral locking plate with orthogonal AP locking screw fixation in the lateral fragment demonstrated the greatest ultimate failure load, followed by the lateral locking plate with CC stabilization. This new plating technique showed compatible stiffness and gap formation when compared to conventional lateral locking plates as well as plates with CC fixation. The use of orthogonal screw fixation in the distal fragment may negate against the need for CC stabilization in these types of fractures, thus minimizing surgical dissection around the coracoid and potential complications.


Subject(s)
Clavicle , Fractures, Bone , Humans , Biomechanical Phenomena , Bone Plates , Cadaver , Clavicle/surgery , Fracture Fixation, Internal/methods , Fractures, Bone/surgery , Ligaments, Articular
2.
Sensors (Basel) ; 23(14)2023 Jul 19.
Article in English | MEDLINE | ID: mdl-37514829

ABSTRACT

Inertial measurement units (IMUs) have become the mainstay in human motion evaluation outside of the laboratory; however, quantification of 3-dimensional upper limb motion using IMUs remains challenging. The objective of this systematic review is twofold. Firstly, to evaluate computational methods used to convert IMU data to joint angles in the upper limb, including for the scapulothoracic, humerothoracic, glenohumeral, and elbow joints; and secondly, to quantify the accuracy of these approaches when compared to optoelectronic motion analysis. Fifty-two studies were included. Maximum joint motion measurement accuracy from IMUs was achieved using Euler angle decomposition and Kalman-based filters. This resulted in differences between IMU and optoelectronic motion analysis of 4° across all degrees of freedom of humerothoracic movement. Higher accuracy has been achieved at the elbow joint with functional joint axis calibration tasks and the use of kinematic constraints on gyroscope data, resulting in RMS errors between IMU and optoelectronic motion for flexion-extension as low as 2°. For the glenohumeral joint, 3D joint motion has been described with RMS errors of 6° and higher. In contrast, scapulothoracic joint motion tracking yielded RMS errors in excess of 10° in the protraction-retraction and anterior-posterior tilt direction. The findings of this study demonstrate high-quality 3D humerothoracic and elbow joint motion measurement capability using IMUs and underscore the challenges of skin motion artifacts in scapulothoracic and glenohumeral joint motion analysis. Future studies ought to implement functional joint axis calibrations, and IMU-based scapula locators to address skin motion artifacts at the scapula, and explore the use of artificial neural networks and data-driven approaches to directly convert IMU data to joint angles.


Subject(s)
Shoulder Joint , Humans , Range of Motion, Articular , Upper Extremity , Motion , Movement , Biomechanical Phenomena
3.
J Hand Surg Am ; 47(11): 1118.e1-1118.e8, 2022 11.
Article in English | MEDLINE | ID: mdl-34690014

ABSTRACT

PURPOSE: Although there is evidence that a single headless compression screw is sufficient for fixation of most scaphoid fractures, double-screw osteosynthesis has been shown to result in higher failure strength and stiffness than a single screw. However, the biomechanical effect of different screw configurations has not been determined. METHODS: A standardized unstable fracture model was produced in 28 cadaveric scaphoids. Specimens were randomly allocated to 1 of 2 fixation groups using 2 internal compression screws positioned in either the sagittal or coronal plane. A specimen-specific 3-dimensionally-printed customized screw placement and osteotomy device was developed using computer-aided design-generated models derived from computed tomography scan data of each individual scaphoid. Load to failure and stiffness of the repair constructs were evaluated using a mechanical testing system. RESULTS: There were no significant differences in size, weight, and density between the scaphoid specimens. The average distance between screws was significantly greater in the sagittal group than in the coronal group. There were no significant differences between the coronal and sagittal aligned double screws in load to 2 mm displacement (mean coronal 180.9 ± 109.7 N; mean sagittal 156.0 ± 85.8 N), load to failure (mean coronal 275.9 ± 150.6 N; mean sagittal 248.0 ± 109.5 N), stiffness (mean coronal 111.7 ± 67.3 N/mm; mean sagittal 101.2 ± 45.1 N/mm), and energy absorption (mean coronal 472.6 ± 261.4 mJ; mean sagittal 443.5 ± 272.7 mJ). CONCLUSIONS: There are no significant biomechanical differences between the sagittal or coronal aligned double headless compression screws in a scaphoid fracture model with bone loss. CLINICAL RELEVANCE: In cases where double-screw fixation of the scaphoid is being considered, the placement of double screws can be at the discretion of the surgeon, and can be dictated by ease of access, surgical preference, and fracture orientation.


Subject(s)
Fractures, Bone , Hand Injuries , Scaphoid Bone , Wrist Injuries , Humans , Scaphoid Bone/diagnostic imaging , Scaphoid Bone/surgery , Scaphoid Bone/injuries , Fractures, Bone/diagnostic imaging , Fractures, Bone/surgery , Bone Screws , Biomechanical Phenomena , Cadaver , Fracture Fixation, Internal/methods
4.
J Shoulder Elbow Surg ; 31(7): 1376-1384, 2022 Jul.
Article in English | MEDLINE | ID: mdl-35167913

ABSTRACT

HYPOTHESIS: Simple transverse or short oblique olecranon fractures without articular comminution are classified as Mayo type IIA fractures and are typically treated with a tension band wire construct. Because of the high reoperation rates, frequently because of prominent hardware, all-suture tension band constructs have been introduced. It was the purpose to compare the biomechanical performance of conventional tension band wire fixation with a new all-suture tension band tape fixation for simple olecranon fractures. METHODS: Mayo type IIA olecranon fractures were created in 20 cadaveric elbows from 10 donors. One elbow of each donor was randomly assigned to the tension band wire technique (group TBW) or tension band tape (Arthrex, 1.3-mm SutureTape) technique (group TBT). Both groups were cyclically loaded with 500 N over 500 cycles, after which a uniaxial displacement was performed to evaluate load to failure. Data were analyzed for gap formation after cyclic loading, construct stiffness, and ultimate load to failure, where failure was defined as fracture gap formation greater than 4.0 mm. RESULTS: There was no significant difference in gap formation after 500 cycles between the TBW (1.8 mm ± 1.3 mm) and the TBT (1.9 mm ± 1.1 mm) groups (P = .854). The TBT showed a tendency toward greater construct stiffness compared with the TBW construct (mean difference: 142 N/mm; P = .053). Ultimate load to failure was not significantly different comparing both groups (TBW: 1138 N ± 286 N vs. TBT: 1126 N ± 272 N; P = .928). In both groups, all repairs failed because of >4.0-mm gap formation at the fracture site and none because of tension band construct breakage. CONCLUSIONS: Our study shows that the TBT technique produces equivalent or superior biomechanical performance to the TBW for simple olecranon fractures. The TBT approach reduces the risk of hardware prominence and as a result mitigates against the need for hardware removal. The TBT technique offers a clinically viable alternative to TBW.


Subject(s)
Fractures, Bone , Olecranon Process , Ulna Fractures , Biomechanical Phenomena , Bone Wires , Fracture Fixation, Internal/methods , Fractures, Bone/surgery , Humans , Olecranon Process/surgery , Sutures , Ulna Fractures/surgery
5.
J Appl Biomech ; 38(6): 365-372, 2022 Dec 01.
Article in English | MEDLINE | ID: mdl-36180043

ABSTRACT

Dual-task walking and cell phone usage, which is associated with high cognitive load and reduced situational awareness, can increase risk of a collision, a fall event, or death. The objective of this study was to quantify the effect of dual-task cell phone talking, texting, and reading while walking on spatiotemporal gait parameters; minimum foot clearance; and dynamic stability of the lower limb joints, trunk, and head. Nineteen healthy male participants walked on an instrumented treadmill at their self-selected speed as well as walking while simultaneously (1) reading on a cell phone, (2) texting, and (3) talking on a cell phone. Gait analyses were performed using an optical motion analysis system, and dynamic stability was calculated using the Maximum Lyapunov Exponent. Dual-task cell phone usage had a significant destabilizing influence on the lower limb joints during walking. Cell phone talking while walking significantly increased step width and length and decreased minimum foot clearance height (P < .05). The findings suggest that dual-task walking and cell phone conversation may present a greater risk of a fall event than texting or reading. This may be due to the requirements for more rapid information processing and cognitive demand at the expense of motor control of joint stability.


Subject(s)
Cell Phone , Text Messaging , Male , Humans , Biomechanical Phenomena , Walking , Gait
6.
Clin J Sport Med ; 30(5): e134-e138, 2020 09.
Article in English | MEDLINE | ID: mdl-30299278

ABSTRACT

OBJECTIVE: This study aimed to investigate the association of self-reported knee stability with symptoms, function, and quality of life in individuals with knee osteoarthritis after anterior cruciate ligament reconstruction (ACLR). SETTING: Cross-sectional. PARTICIPANTS: Twenty-eight individuals with knee osteoarthritis, 5 to 12 years after ACLR. MAIN OUTCOME MEASURES: Self-reported knee stability was assessed using visual analogue scales (VAS) during hop for distance (HD), side-to-side hop (SSH), and one-leg rise (OLR). Symptoms [Knee Injury and Osteoarthritis Outcome Score (KOOS) pain, Anterior Knee Pain Scale (AKPS), and International Knee Documentation Committee form], self-reported function (KOOS-sport/rec), performance-based function (hopping and OLR), and quality of life (KOOS-QOL) were assessed. K-means clustering categorized individuals into low (n = 8) and high self-reported knee stability (n = 20) groups based on participants' VAS scores during functional tasks. RESULTS: The low self-reported knee stability group had worse knee symptoms than the high self-reported knee stability group [KOOS-pain: mean difference -17 (95% confidence interval, -28 to -5); AKPS: -10 (-20 to -1)], and worse self-reported function [KOOS-sport/rec: -33 (-48 to -18)] and performance-based function [HD: -28 (-53 to -3); SSH: -10 (-20 to -1), OLR: -18 (-32 to -50)]. CONCLUSION: Low self-reported stability is associated with worse symptoms, and worse self-reported and performance-based function. Further research is required to determine the causation relation of self-reported knee stability to knee symptoms and function in individuals with knee osteoarthritis after ACLR.


Subject(s)
Anterior Cruciate Ligament Reconstruction/adverse effects , Joint Instability/physiopathology , Osteoarthritis, Knee/physiopathology , Postoperative Complications/physiopathology , Quality of Life , Self Report , Adult , Arthralgia/diagnosis , Cross-Sectional Studies , Exercise , Female , Humans , Joint Instability/etiology , Knee Joint , Male , Middle Aged , Osteoarthritis, Knee/etiology , Osteoarthritis, Knee/psychology , Pain Measurement/methods , Postoperative Complications/etiology , Postoperative Complications/psychology , Symptom Assessment , Time Factors , Visual Analog Scale
7.
J Hand Surg Am ; 45(12): 1185.e1-1185.e8, 2020 Dec.
Article in English | MEDLINE | ID: mdl-32723573

ABSTRACT

PURPOSE: High bone density and quality is associated with improved screw fixation in fracture fixation. The objective of this study was to assess bone density and quality in the proximal and distal scaphoid to determine optimum sites for placement of 2 screws in scaphoid fracture fixation. METHODS: Twenty-nine cadaveric human scaphoid specimens were harvested and scanned using micro-computed tomography. Bone density (bone volume fraction) and bone quality (relative bone surface area, trabecular number, and trabecular thickness) were evaluated in 4 quadrants within each of the proximal and distal scaphoid. RESULTS: The proximal radial quadrant of the scaphoid had significantly greater bone volume than the distal ulnar (mean difference, 33.2%) and distal volar quadrants (mean difference, 32.3%). There was a significantly greater trabecular number in the proximal radial quadrant than in the distal ulnar (mean difference, 16.7%) and in the distal volar quadrants (mean difference, 15.9%) and between the proximal ulnar and the distal ulnar quadrants (mean difference, 12%). There was a significantly greater bone surface area in the proximal radial and distal radial quadrants than in the distal ulnar and distal volar quadrants. There were no significant differences in trabecular thickness between the 8 analyzed quadrants CONCLUSIONS: Although there are differences in bone volume, trabecular number, and bone surface area between the proximal pole of the scaphoid and that of the distal pole, there were no significant differences in the bone quality (trabecular thickness, trabecular number, and relative bone surface area) and density (bone volume fraction) between the 4 quadrants of the proximal or distal pole of the cadaveric scaphoids studied. CLINICAL RELEVANCE: Insertion of 2 headless compression screws can be determined by ease of surgical access and ease of screw positioning and not by differences in bone quality or density of the proximal or distal scaphoid.


Subject(s)
Fractures, Bone , Scaphoid Bone , Bone Screws , Fracture Fixation, Internal , Fractures, Bone/diagnostic imaging , Fractures, Bone/surgery , Humans , Scaphoid Bone/diagnostic imaging , Scaphoid Bone/surgery , X-Ray Microtomography
8.
J Anat ; 234(1): 1-15, 2019 01.
Article in English | MEDLINE | ID: mdl-30411350

ABSTRACT

The moment arm of a muscle represents its leverage or torque-producing capacity, and is indicative of the role of the muscle in joint actuation. The objective of this study was to undertake a systematic review of the moment arms of the major muscles spanning the glenohumeral joint during abduction, flexion and axial rotation. Moment arm data for the deltoid, pectoralis major, latissimus dorsi, teres major, supraspinatus, infraspinatus, subscapularis and teres minor were reported when measured using the geometric and tendon excursion methods. The anterior and middle sub-regions of the deltoid had the largest humeral elevator moment arm values of all muscles during coronal- and scapular-plane abduction, as well as during flexion. The pectoralis major, latissimus dorsi and teres major had the largest depressor moment arms, with each of these muscles exhibiting prominent leverage in shoulder adduction, and the latissimus dorsi and teres major also in extension. The rotator cuff muscles had the largest axial rotation moment arms regardless of the axial position of the humerus. The supraspinatus had the most prominent elevator moment arms during early abduction in both the coronal and scapular planes as well as in flexion. This systematic review shows that the rotator cuff muscles function as humeral rotators and weak humeral depressors or elevators, while the three sub-regions of the deltoid behave as substantial humeral elevators throughout the range of humeral motion. The pectoralis major, latissimus dorsi and teres major are significant shoulder depressors, particularly during abduction. This study provides muscle moment arm data on functionally relevant shoulder movements that are involved in tasks of daily living, including lifting and pushing. The results may be useful in quantifying shoulder muscle function during specific planes of movement, in designing and validating computational models of the shoulder, and in planning surgical procedures such as tendon transfer surgery.


Subject(s)
Arm/physiology , Movement/physiology , Muscle, Skeletal/physiology , Range of Motion, Articular/physiology , Shoulder Joint/physiology , Biomechanical Phenomena/physiology , Humans
9.
J Hand Surg Am ; 43(3): 221-228, 2018 03.
Article in English | MEDLINE | ID: mdl-29132789

ABSTRACT

PURPOSE: Union of a scaphoid fracture after fixation is influenced by various factors, one of which is fracture stability. This study aims to compare the biomechanical stability of 3 different types of scaphoid fracture fixation in a scaphoid nonunion model. METHODS: Thirty cadaveric scaphoid specimens were assigned to one of 3 different fixation groups: (1) single 3.0-mm compression screw, (2) two 2.2-mm screws, and (3) scaphoid plate. A 3-mm volar wedge osteotomy was created at the scaphoid waist to simulate a nonunion model. The primary outcome measure was load to failure, whereas secondary outcome measures were load to 2-mm displacement, energy absorbed, stiffness, and mode of failure, recorded by video and retrieval analysis. RESULTS: There was a significantly lower load to failure in the single screw construct compared with that in the double screw (mean difference 187.2 N) and plate fixation constructs (mean difference 150.7 N). The mean load to 2-mm displacement in the single screw construct (91.5 N) was also significantly lower than that in the double screw (181.8 N) and plate fixation constructs (197.2 N). There was a significantly lower stiffness with the single screw fixation compared with that of the double screws (mean difference 85.4 N/mm), and lower energy absorbed with single screws when compared with that of double screws (mean difference 386.5 mJ) and when compared with plate fixation (mean difference 270.8 mJ). CONCLUSIONS: In this biomechanical study comparing fixation methods using a model of scaphoid nonunion with bone loss, we found that double screws or plate fixation demonstrated significantly greater stability, stiffness, and energy absorption when compared with a single compression screw. We found no discernible differences between double screw fixation and the plate groups. CLINICAL RELEVANCE: The use of double screws or plate fixation in a nonunion setting may allow accelerated rehabilitation without compromise to fracture stability.


Subject(s)
Fracture Fixation, Internal/instrumentation , Fractures, Ununited/surgery , Materials Testing , Scaphoid Bone/surgery , Bone Plates , Bone Screws , Cadaver , Humans , Scaphoid Bone/injuries , Stress, Mechanical
10.
J Shoulder Elbow Surg ; 27(11): 2085-2092, 2018 Nov.
Article in English | MEDLINE | ID: mdl-29954661

ABSTRACT

BACKGROUND: Rotator cuff tears following anatomic total shoulder arthroplasty increase with duration of follow-up. This study aimed to evaluate contact pressure between the rotator cuff tendons and prosthesis after anatomic total shoulder arthroplasty and compare these with the tendon-contact pressures in the native shoulder. METHODS: Eight entire upper extremities were mounted onto a testing apparatus, and simulated muscle loading was applied to each rotator cuff tendon with the shoulder positioned in abduction, internal rotation, and external rotation. Pressure-sensitive film placed between each tendon and bone was used to measure the resultant tendon contact pressures. Experiments were repeated after anatomic total shoulder arthroplasty using standardized implant sizes, and pressure-sensitive film was used to evaluate tendon-prosthesis contact pressure. RESULTS: Both joint angle and shoulder joint replacement surgery had significant effects on the maximum contact pressure measured between the humeral head and all rotator cuff tendons (P < .05) except the teres minor. The supraspinatus demonstrated a significantly larger peak tendon contact pressure after surgery at 45° of abduction relative to that in the native shoulder (mean difference, 0.2 MPa; P = .031), while the subscapularis had a significantly larger maximum contact pressure at 10° of abduction (mean difference, 0.45 MPa; P = .032) and 90° of abduction (mean difference, 0.80 MPa; P = .008) postoperatively. CONCLUSION: Anatomic total shoulder arthroplasty results in significantly larger tendon contact pressures relative to those in the native shoulder. High tendon contact pressures may ultimately predispose rotator cuff tendons to postoperative wear-induced damage and tearing.


Subject(s)
Arthroplasty, Replacement, Shoulder/instrumentation , Rotator Cuff Injuries/etiology , Rotator Cuff/pathology , Shoulder Prosthesis , Aged , Arthroplasty, Replacement, Shoulder/adverse effects , Cadaver , Humans , Humeral Head/surgery , Middle Aged , Pressure , Range of Motion, Articular , Scapula/surgery
11.
BMC Bioinformatics ; 18(Suppl 16): 571, 2017 12 28.
Article in English | MEDLINE | ID: mdl-29297295

ABSTRACT

BACKGROUND: In metagenomics, the separation of nucleotide sequences belonging to an individual or closely matched populations is termed binning. Binning helps the evaluation of underlying microbial population structure as well as the recovery of individual genomes from a sample of uncultivable microbial organisms. Both supervised and unsupervised learning methods have been employed in binning; however, characterizing a metagenomic sample containing multiple strains remains a significant challenge. In this study, we designed and implemented a new workflow, Coverage and composition based binning of Metagenomes (CoMet), for binning contigs in a single metagenomic sample. CoMet utilizes coverage values and the compositional features of metagenomic contigs. The binning strategy in CoMet includes the initial grouping of contigs in guanine-cytosine (GC) content-coverage space and refinement of bins in tetranucleotide frequencies space in a purely unsupervised manner. With CoMet, the clustering algorithm DBSCAN is employed for binning contigs. The performances of CoMet were compared against four existing approaches for binning a single metagenomic sample, including MaxBin, Metawatt, MyCC (default) and MyCC (coverage) using multiple datasets including a sample comprised of multiple strains. RESULTS: Binning methods based on both compositional features and coverages of contigs had higher performances than the method which is based only on compositional features of contigs. CoMet yielded higher or comparable precision in comparison to the existing binning methods on benchmark datasets of varying complexities. MyCC (coverage) had the highest ranking score in F1-score. However, the performances of CoMet were higher than MyCC (coverage) on the dataset containing multiple strains. Furthermore, CoMet recovered contigs of more species and was 18 - 39% higher in precision than the compared existing methods in discriminating species from the sample of multiple strains. CoMet resulted in higher precision than MyCC (default) and MyCC (coverage) on a real metagenome. CONCLUSIONS: The approach proposed with CoMet for binning contigs, improves the precision of binning while characterizing more species in a single metagenomic sample and in a sample containing multiple strains. The F1-scores obtained from different binning strategies vary with different datasets; however, CoMet yields the highest F1-score with a sample comprised of multiple strains.


Subject(s)
Algorithms , Contig Mapping , Metagenomics/methods , Workflow , Base Sequence , Cluster Analysis , Databases, Genetic , Genome , Humans , Metagenome
12.
Br J Sports Med ; 50(10): 597-612, 2016 May.
Article in English | MEDLINE | ID: mdl-26265562

ABSTRACT

BACKGROUND: Abnormal gait after anterior cruciate ligament reconstruction (ACLR) may contribute to development and/or progression of knee osteoarthritis. OBJECTIVE: To conduct a systematic review and meta-analysis of knee kinematics and joint moments during walking after ACLR. METHODS: We searched seven electronic databases and reference lists of relevant papers, for cross-sectional, human-based observational studies comparing knee joint kinematics and moments during level walking in individuals with ACLR, with the uninjured contralateral knee or healthy individuals as a control. Two independent reviewers appraised methodological quality (modified Downs and Black scale). Where possible, data were pooled by time post-ACLR (RevMan), otherwise narrative synthesis was undertaken. RESULTS: Thirty-four studies were included. Meta-analysis revealed significant sagittal plane deficits in ACLR knees. We found greater knee flexion angles (standardised mean difference: 1.06; 95% CI 0.39 to 1.74) and joint moments (1.61; 0.87 to 2.35) <6 months post-ACLR, compared to healthy controls. However, lower peak knee flexion angles were identified 1-3 years (-2.21; -3.16 to -1.26) and ≥3 years post-ACLR (-1.38, -2.14 to -0.62), and lower knee flexion moment 6-12 months post-ACLR (-0.76; -1.40 to -0.12). Pooled data provided strong evidence of no difference in peak knee adduction moment >3 years after ACLR (vs healthy controls) (0.09; -0.63 to 0.81). No transverse plane conclusions could be drawn. CONCLUSIONS: Sagittal plane biomechanics, rather than the knee adduction moment, appear to be more relevant post-ACLR. Better understanding of sagittal plane biomechanics is necessary for optimal post-operative recovery, and to potentially prevent early onset and progression of knee OA after ACLR. TRIAL REGISTRATION NUMBER: PROSPERO systematic review protocol registration number CRD4201400882 2.


Subject(s)
Anterior Cruciate Ligament Injuries/physiopathology , Anterior Cruciate Ligament Reconstruction , Gait/physiology , Knee Joint/physiology , Anterior Cruciate Ligament Injuries/surgery , Biomechanical Phenomena/physiology , Humans , Postoperative Period
13.
J Appl Biomech ; 32(2): 128-39, 2016 Apr.
Article in English | MEDLINE | ID: mdl-26426798

ABSTRACT

Normalization of gait data is performed to reduce the effects of intersubject variations due to physical characteristics. This study reports a multiple regression normalization approach for spatiotemporal gait data that takes into account intersubject variations in self-selected walking speed and physical properties including age, height, body mass, and sex. Spatiotemporal gait data including stride length, cadence, stance time, double support time, and stride time were obtained from healthy subjects including 782 children, 71 adults, 29 elderly subjects, and 28 elderly Parkinson's disease (PD) patients. Data were normalized using standard dimensionless equations, a detrending method, and a multiple regression approach. After normalization using dimensionless equations and the detrending method, weak to moderate correlations between walking speed, physical properties, and spatiotemporal gait features were observed (0.01 < |r| < 0.88), whereas normalization using the multiple regression method reduced these correlations to weak values (|r| <0.29). Data normalization using dimensionless equations and detrending resulted in significant differences in stride length and double support time of PD patients; however the multiple regression approach revealed significant differences in these features as well as in cadence, stance time, and stride time. The proposed multiple regression normalization may be useful in machine learning, gait classification, and clinical evaluation of pathological gait patterns.


Subject(s)
Data Interpretation, Statistical , Gait Disorders, Neurologic/physiopathology , Gait , Parkinson Disease/physiopathology , Spatio-Temporal Analysis , Walking , Adolescent , Aged , Aged, 80 and over , Algorithms , Child , Child, Preschool , Female , Gait Disorders, Neurologic/diagnosis , Gait Disorders, Neurologic/etiology , Humans , Machine Learning , Male , Middle Aged , Parkinson Disease/complications , Parkinson Disease/diagnosis , Pattern Recognition, Automated , Physical Examination/methods , Regression Analysis , Reproducibility of Results , Sensitivity and Specificity
14.
J Biomech Eng ; 137(4): 041001, 2015 Apr.
Article in English | MEDLINE | ID: mdl-25565306

ABSTRACT

One of the most widely reported complications associated with temporomandibular joint (TMJ) prosthetic total joint replacement (TJR) surgery is condylar component screw loosening and instability. The objective of this study was to develop a musculoskeletal model of the human jaw to assess the influence of prosthetic condylar component orientation and screw placement on condylar component loading during mastication. A three-dimensional model of the jaw comprising the maxilla, mandible, masticatory muscles, articular cartilage, and articular disks was developed. Simulations of mastication and a maximum force bite were performed for the natural TMJ and the TMJ after prosthetic TJR surgery, including cases for mastication where the condylar component was rotated anteriorly by 0 deg, 5 deg, 10 deg, and 15 deg. Three clinically significant screw configurations were investigated: a complete, posterior, and minimal-posterior screw (MPS) configuration. Increases in condylar anterior rotation led to an increase in prosthetic condylar component contact stresses and substantial increases in condylar component screw stresses. The use of more screws in condylar fixation reduced screw stress magnitudes and maximum condylar component stresses. Screws placed superiorly experienced higher stresses than those of all other condylar fixation screws. The results of the present study have important implication for the way in which prosthetic components are placed during TMJ prosthetic TJR surgery.


Subject(s)
Arthroplasty, Replacement , Joint Prosthesis , Models, Anatomic , Muscles/anatomy & histology , Temporomandibular Joint/anatomy & histology , Temporomandibular Joint/surgery , Bone Screws , Finite Element Analysis , Humans , Male , Mandibular Condyle/anatomy & histology , Mandibular Condyle/physiology , Muscles/physiology , Stress, Mechanical , Temporomandibular Joint/physiology , Weight-Bearing
15.
Knee Surg Sports Traumatol Arthrosc ; 23(2): 619-26, 2015 Feb.
Article in English | MEDLINE | ID: mdl-25502979

ABSTRACT

PURPOSE: Re-establishment of the native footprint during rotator cuff repair is important for maximizing healing potential and fixation strength. The purpose of this study was to evaluate the contact area, contact pressure, stiffness and tensile strength of a new single-row cruciate suture repair and to compare these results to those of the Mason-Allen, double-row and transosseous repairs. METHODS: Infraspinatus tendons from fifty-six lamb shoulders were harvested and randomly assigned to cruciate suture, Mason-Allen, double-row and transosseous repair groups. Repairs were performed over pressure-sensitive film and footprint contact area and pressure measured. Repaired tendon specimens were also loaded in uniaxial tension, and ultimate tensile strength and stiffness measured. RESULTS: The cruciate suture repair established significantly greater footprint contact area compared to the Mason-Allen repair (mean difference = 101 mm(2), p = 0.003). The ultimate tensile strength and stiffness of the double-row repair was significantly higher than that of all other repair groups (p < 0.05). The average footprint contact pressure of the cruciate suture repair (0.78 MPa) was similar to that of the Mason-Allen (0.74 MPa) and double-row repairs (0.79 MPa). The ultimate tensile strength of the cruciate suture repair was significantly greater than that of the transosseous repair (mean difference 62.4 N, p = 0.002). CONCLUSION: The cruciate suture repair may improve strength and healing at the repaired tendon rotator cuff insertion relative to other single-row repair techniques. It may represent a faster, easier and more cost-effective alternative to double-row repairs.


Subject(s)
Rotator Cuff/surgery , Suture Techniques , Tendon Injuries/surgery , Animals , Disease Models, Animal , Male , Rotator Cuff/physiopathology , Rotator Cuff Injuries , Sheep , Tendon Injuries/physiopathology , Tensile Strength
16.
Vet Surg ; 44(1): 94-102, 2015 Jan.
Article in English | MEDLINE | ID: mdl-25209367

ABSTRACT

OBJECTIVE: To 1) assess the bending strength and stiffness of canine cadaver spines after fixation of a lumbar spinal fracture-luxation using a novel unilateral stabilization technique with pins and polymethyl methacrylate (PMMA) and 2) compare the results to a reference standard dorsal pin and PMMA technique. STUDY DESIGN: A randomized non-inferiority trial. SAMPLE POPULATION: Cadaveric lumbar spines (L1-L6) from 20 Greyhounds. METHODS: Specimens were paired to match bodyweight and vertebral size. A standardized fracture/luxation was performed between L3 and L4. One spine within each pair was randomly assigned the unilateral fixation technique and the other received the reference standard dorsal fixation technique. Four-point bending of each specimen in flexion was performed by applying load to pins placed transversely into vertebrae L1, L2, L5, and L6. During testing, angular bending strength and stiffness were measured as a function of flexion angle. Margins for non-inferiority were defined a priori. Strength and stiffness of the specimens for each technique were compared statistically. RESULTS: Lower limits of 95% confidence intervals were above the defined margins for non-inferiority. Thus, based on these margins, for strength and stiffness, unilateral fixation was not inferior to dorsal fixation. CONCLUSIONS: This novel unilateral approach to lumbar spinal fixation yielded comparable strength and stiffness when tested for bending in flexion to that of reference standard dorsal approach. This approach is therefore a suitable alternative to the dorsal approach in appropriate lumbar spinal fracture configurations.


Subject(s)
Bone Screws/veterinary , Dogs/surgery , Spinal Fractures/veterinary , Spinal Fusion/veterinary , Animals , Biomechanical Phenomena , Cadaver , Dogs/injuries , Internal Fixators/veterinary , Lumbar Vertebrae/surgery , Range of Motion, Articular , Spinal Fractures/surgery , Spinal Fusion/instrumentation
17.
J Biomech ; 172: 112178, 2024 Jul.
Article in English | MEDLINE | ID: mdl-38959820

ABSTRACT

Reactive lower limb muscle function during walking plays a key role in balance recovery following tripping, and ultimately fall prevention. The objective of this study was to evaluate muscle and joint function in the recovery limb during balance recovery after trip-based perturbations during walking. Twenty-four healthy participants underwent gait analysis while walking at slow, moderate and fast speeds over level, uphill and downhill inclines. Trip perturbations were performed randomly during stance, and lower limb kinematics, kinetics, and muscle contribution to the acceleration of the whole-body centre of mass (COM) were computed pre- and post-perturbation in the recovery limb. Ground slope and walking speed had a significant effect on lower limb joint angles, net joint moments and muscle contributions to support and propulsion during trip recovery (p < 0.05). Specifically, increasing walking speed during trip recovery significantly reduced hip extension in the recovery limb and increased knee flexion, particularly when walking uphill and at higher walking speeds (p < 0.05). Gluteus maximus played a critical role in providing support and forward propulsion of the body during trip recovery across all gait speeds and ground inclinations. This study provides a mechanistic link between muscle action, joint motion and COM acceleration during trip recovery, and underscores the potential of increased walking speed and ground inclination to increase fall risk, particularly in individuals prone to falling. The findings of this study may provide guidelines for targeted exercise therapy such as muscle strengthening for fall prevention.


Subject(s)
Accidental Falls , Gait , Muscle, Skeletal , Postural Balance , Walking Speed , Humans , Male , Female , Postural Balance/physiology , Muscle, Skeletal/physiology , Walking Speed/physiology , Gait/physiology , Adult , Accidental Falls/prevention & control , Biomechanical Phenomena , Walking/physiology , Knee Joint/physiology , Hip Joint/physiology
18.
J Orthop Res ; 42(3): 588-597, 2024 Mar.
Article in English | MEDLINE | ID: mdl-37812185

ABSTRACT

Subacromial impingement (SAI) is associated with shoulder pain and dysfunction and is exacerbated by rotator cuff tears; however, the role of acromioplasty in mitigating subacromial contact in the rotator cuff deficient shoulder remains debated. This study aimed to quantify the influence of isolated and combined tears involving the supraspinatus on subacromial contact during abduction; and second, to evaluate the influence of acromioplasty on joint space size and subacromial contact under these pathological conditions. Eight fresh-frozen human cadaveric upper limbs were mounted to a computer-controlled testing apparatus that simulated joint motion by simulated force application. Shoulder abduction was performed while three-dimensional joint kinematics was measured using an optoelectronic system, and subacromial contact evaluated using a digital pressure sensor secured to the inferior acromion. Testing was performed after an isolated tear to the supraspinatus, as well as tears involving the subscapularis and infraspinatus-teres minor, both before and after acromioplasty. Rotator cuff tears significantly increased peak subacromial pressure (p < 0.001), average subacromial pressure (p = 0.001), and contact force (p = 0.034) relative to those in the intact shoulder. Following acromioplasty, significantly lower peak subacromial contact pressure, force and area were observed for all rotator cuff tears involving the supraspinatus at 30° of abduction (p < 0.05). Acromioplasty predominantly reduces acromion thickness anteriorly thereby reducing subacromial contact in the rotator cuff deficient shoulder, particularly in early to mid-abduction where superior glenohumeral joint shear force potential is large. These findings provide a biomechanical basis for acromioplasty as an intervention for SAI syndrome and as an adjunct to rotator cuff repairs.


Subject(s)
Rotator Cuff Injuries , Shoulder Joint , Humans , Rotator Cuff/surgery , Shoulder , Rotator Cuff Injuries/surgery , Rupture , Biomechanical Phenomena , Cadaver , Range of Motion, Articular
19.
J Hand Surg Asian Pac Vol ; 29(5): 418-423, 2024 Oct.
Article in English | MEDLINE | ID: mdl-39205518

ABSTRACT

Background: The aim of this study was to evaluate the chicken femur as a laboratory model for the human metacarpal by comparing the bone microarchitecture and mechanical properties of chicken femurs to human cadaveric metacarpals. Methods: Sixteen fresh chicken femora and 20 fresh frozen cadaveric human metacarpals were imaged using a micro computed tomography scanner. The bones were then mechanically tested using four-point-bending and torsional testing. Results: There were no significant differences in macroscopic features between chicken femora and human metacarpals, including overall length, external radius, internal radius, cortical width and cross-sectional area of the diaphyseal cortex (p > 0.05). There were no significant differences in the trabecular number and spacing in the distal metaphysis of both groups (p > 0.05). The diaphysis and proximal metaphysis did not share any microarchitectural similarities. Four-point bending tests resulted in significantly higher yield forces, ultimate force, failure points and stiffness in human metacarpals (p < 0.05). Torsion tests resulted in significant higher ultimate torque and torsional rigidity in human metacarpals (p < 0.05). Conclusions: The chicken femur has structural and biomechanical differences to the fresh frozen human metacarpal despite the similarity in their macroscopic features.


Subject(s)
Cadaver , Chickens , Femur , Metacarpal Bones , Animals , Humans , Metacarpal Bones/diagnostic imaging , Metacarpal Bones/anatomy & histology , Femur/diagnostic imaging , Femur/anatomy & histology , Femur/physiology , Biomechanical Phenomena , X-Ray Microtomography , Models, Animal
20.
J Orthop Res ; 2024 Jun 12.
Article in English | MEDLINE | ID: mdl-38864683

ABSTRACT

Full-thickness rotator cuff tears can lead to poor coaptation of the humeral head to the glenoid, disrupting muscle forces required for glenohumeral joint stability, ultimately leading to joint subluxation. The aim of this study was to evaluate muscle forces and glenohumeral joint translations during elevation in the presence of isolated and combined full-thickness rotator cuff tears. Eight fresh-frozen upper limbs were mounted to a computer-controlled testing apparatus that simulated joint motion by simulated muscle force application. Scapular-plane abduction was performed, and glenohumeral joint translations were measured using an optoelectronic system. Testing was performed in the native shoulder, a following an isolated tear to the supraspinatus, as well as combined tears involving the supraspinatus and subscapularis, as well as supraspinatus, infraspinatus, and teres minor. Rotator cuff tears significantly increased middle deltoid force at 30°, 60°, and 90° of abduction relative to that in the native shoulder (p < 0.05). Significantly greater superior translations were observed relative to the intact shoulder due to combined tears to the supraspinatus and infraspinatus at 30° of abduction (mean increase: 1.6 mm, p = 0.020) and 60° of abduction (mean increase: 4.8 mm, p = 0.040). This study illustrates the infraspinatus-teres minor complex as a major humeral head depressor and contributor to glenohumeral joint stability. An increase in deltoid force during abduction occurs in the presence of rotator cuff tears, which exacerbates superior migration of the humeral head. The findings may help in the development of clinical tests in rotator cuff tear diagnostics, in surgical planning of rotator cuff repair, and in planning of targeted rehabilitation.

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