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1.
Inosine pranobex enhances human NK cell cytotoxicity by inducing metabolic activation and NKG2D ligand expression.
Eur J Immunol
; 50(1): 130-137, 2020 01.
Article
in English
| MEDLINE | ID: mdl-31434164
2.
Recent advances in the biology of tumour hypoxia with relevance to diagnostic practice and tissue-based research.
J Pathol
; 250(5): 593-611, 2020 04.
Article
in English
| MEDLINE | ID: mdl-32086807
3.
Purine nucleotide metabolism regulates expression of the human immune ligand MICA.
J Biol Chem
; 293(11): 3913-3924, 2018 03 16.
Article
in English
| MEDLINE | ID: mdl-29279329
4.
Remodelling of microRNAs in colorectal cancer by hypoxia alters metabolism profiles and 5-fluorouracil resistance.
Hum Mol Genet
; 26(8): 1552-1564, 2017 04 15.
Article
in English
| MEDLINE | ID: mdl-28207045
5.
PHD2 inactivation in Type I cells drives HIF-2α-dependent multilineage hyperplasia and the formation of paraganglioma-like carotid bodies.
J Physiol
; 2018 Jun 19.
Article
in English
| MEDLINE | ID: mdl-29917232
6.
Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase.
Nature
; 477(7363): 225-8, 2011 Aug 17.
Article
in English
| MEDLINE | ID: mdl-21849978
7.
OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation.
Proc Natl Acad Sci U S A
; 111(11): 4031-6, 2014 Mar 18.
Article
in English
| MEDLINE | ID: mdl-24550447
8.
Loss of Fumarate Hydratase and Aberrant Protein Succination Detected With S-(2-Succino)-Cysteine Staining to Identify Patients With Multiple Cutaneous and Uterine Leiomyomatosis and Hereditary Leiomyomatosis and Renal Cell Cancer Syndrome.
Am J Dermatopathol
; 38(12): 887-891, 2016 Dec.
Article
in English
| MEDLINE | ID: mdl-27097334
9.
Oncogenic Cell Tagging and Single-Cell Transcriptomics Reveal Cell Type-Specific and Time-Resolved Responses to Vhl Inactivation in the Kidney.
Cancer Res
; 84(11): 1799-1816, 2024 Jun 04.
Article
in English
| MEDLINE | ID: mdl-38502859
10.
Dysregulation of hypoxia pathways in fumarate hydratase-deficient cells is independent of defective mitochondrial metabolism.
Hum Mol Genet
; 19(19): 3844-51, 2010 Oct 01.
Article
in English
| MEDLINE | ID: mdl-20660115
11.
In the ring with polycystic kidney disease--avoiding the knockout punch.
J Pathol
; 223(1): 1-3, 2011 Jan.
Article
in English
| MEDLINE | ID: mdl-20938930
12.
Aberrant succination of proteins in fumarate hydratase-deficient mice and HLRCC patients is a robust biomarker of mutation status.
J Pathol
; 225(1): 4-11, 2011 Sep.
Article
in English
| MEDLINE | ID: mdl-21630274
13.
Somatostatin secretion by Na+-dependent Ca2+-induced Ca2+ release in pancreatic delta-cells.
Nat Metab
; 2(1): 32-40, 2020 01.
Article
in English
| MEDLINE | ID: mdl-31993555
14.
Dysregulation of Glucagon Secretion by Hyperglycemia-Induced Sodium-Dependent Reduction of ATP Production.
Cell Metab
; 29(2): 430-442.e4, 2019 02 05.
Article
in English
| MEDLINE | ID: mdl-30415925
15.
Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion.
Nat Commun
; 10(1): 139, 2019 01 11.
Article
in English
| MEDLINE | ID: mdl-30635569
16.
A role for Xrcc2 in the early stages of mouse development.
DNA Repair (Amst)
; 6(2): 224-34, 2007 Feb 04.
Article
in English
| MEDLINE | ID: mdl-17116431
17.
Succination of Protein Disulfide Isomerase Links Mitochondrial Stress and Endoplasmic Reticulum Stress in the Adipocyte During Diabetes.
Antioxid Redox Signal
; 27(16): 1281-1296, 2017 Dec 01.
Article
in English
| MEDLINE | ID: mdl-28376661
18.
Fumarate Hydratase Deletion in Pancreatic ß Cells Leads to Progressive Diabetes.
Cell Rep
; 20(13): 3135-3148, 2017 Sep 26.
Article
in English
| MEDLINE | ID: mdl-28954230
19.
Increased Expression of the Diabetes Gene SOX4 Reduces Insulin Secretion by Impaired Fusion Pore Expansion.
Diabetes
; 65(7): 1952-61, 2016 07.
Article
in English
| MEDLINE | ID: mdl-26993066
20.
Expression of Idh1R132H in the Murine Subventricular Zone Stem Cell Niche Recapitulates Features of Early Gliomagenesis.
Cancer Cell
; 30(4): 578-594, 2016 10 10.
Article
in English
| MEDLINE | ID: mdl-27693047