Search | Virtual Health Library

1.

S1-END-seq reveals DNA secondary structures in human cells.

Matos-Rodrigues, Gabriel; van Wietmarschen, Niek; Wu, Wei; Tripathi, Veenu; Koussa, Natasha C; Pavani, Raphael; Nathan, William J; Callen, Elsa; Belinky, Frida; Mohammed, Ashraf; Napierala, Marek; Usdin, Karen; Ansari, Aseem Z; Mirkin, Sergei M; Nussenzweig, André.

Mol Cell ; 82(19): 3538-3552.e5, 2022 10 06.

Article in English | MEDLINE | ID: mdl-36075220

2.

A partner evokes latent differences between Hox proteins.

Ansari, Aseem Z; Peterson-Kaufman, Kimberly J.

Cell ; 147(6): 1220-1, 2011 Dec 09.

Article in English | MEDLINE | ID: mdl-22153067

3.

Using synthetic genome readers/regulators to interrogate chromatin processes: A brief review.

Philips, Steven J; Danda, Adithi; Ansari, Aseem Z.

Methods ; 225: 20-27, 2024 May.

Article in English | MEDLINE | ID: mdl-38471600

4.

Engineered Covalent Inactivation of TFIIH-Kinase Reveals an Elongation Checkpoint and Results in Widespread mRNA Stabilization.

Rodríguez-Molina, Juan B; Tseng, Sandra C; Simonett, Shane P; Taunton, Jack; Ansari, Aseem Z.

Mol Cell ; 63(3): 433-44, 2016 08 04.

Article in English | MEDLINE | ID: mdl-27477907

5.

Domain-Selective BET Ligands Yield Next-Generation Synthetic Genome Readers/Regulators with Nonidentical Cellular Functions.

Mohammed, Ashraf; Waddell, M Brett; Sutkeviciute, Ieva; Danda, Adithi; Philips, Steven J; Lang, Walter; Slavish, P Jake; Kietlinska, Sandra J; Kaulage, Mangesh; Sourav, Das; Ansari, Aseem Z.

J Am Chem Soc ; 2023 Nov 03.

Article in English | MEDLINE | ID: mdl-37923569

6.

In search of chemical rationales.

Ansari, Aseem Z.

Nat Chem Biol ; 20(3): 264-265, 2024 Mar.

Article in English | MEDLINE | ID: mdl-38030787

7.

Noncanonical CTD kinases regulate RNA polymerase II in a gene-class-specific manner.

Nemec, Corey M; Singh, Amit K; Ali, Asfa; Tseng, Sandra C; Syal, Kirtimaan; Ringelberg, Kennedy J; Ho, Yi-Hsuan; Hintermair, Corinna; Ahmad, Mohammad Faiz; Kar, Rajesh Kumar; Gasch, Audrey P; Akhtar, Md Sohail; Eick, Dirk; Ansari, Aseem Z.

Nat Chem Biol ; 15(2): 123-131, 2019 02.

Article in English | MEDLINE | ID: mdl-30598543

8.

Har Gobind Khorana 1922-2011.

Ansari, Aseem Z; Rosner, Marsha Rich; Adler, Julius.

Cell ; 147(7): 1433-5, 2011 Dec 23.

Article in English | MEDLINE | ID: mdl-22355806

9.

De novo design of programmable inducible promoters.

Liu, Xiangyang; Gupta, Sanjan T P; Bhimsaria, Devesh; Reed, Jennifer L; Rodríguez-Martínez, José A; Ansari, Aseem Z; Raman, Srivatsan.

Nucleic Acids Res ; 47(19): 10452-10463, 2019 11 04.

Article in English | MEDLINE | ID: mdl-31552424

10.

Specificity landscapes unmask submaximal binding site preferences of transcription factors.

Bhimsaria, Devesh; Rodríguez-Martínez, José A; Pan, Junkun; Roston, Daniel; Korkmaz, Elif Nihal; Cui, Qiang; Ramanathan, Parameswaran; Ansari, Aseem Z.

Proc Natl Acad Sci U S A ; 115(45): E10586-E10595, 2018 11 06.

Article in English | MEDLINE | ID: mdl-30341220

11.

A chemoprobe tracks its target.

Ansari, Aseem Z.

J Biol Chem ; 294(20): 8323-8324, 2019 05 17.

Article in English | MEDLINE | ID: mdl-31101661

12.

Flexibility and structure of flanking DNA impact transcription factor affinity for its core motif.

Yella, Venkata Rajesh; Bhimsaria, Devesh; Ghoshdastidar, Debostuti; Rodríguez-Martínez, José A; Ansari, Aseem Z; Bansal, Manju.

Nucleic Acids Res ; 46(22): 11883-11897, 2018 12 14.

Article in English | MEDLINE | ID: mdl-30395339

13.

Different phosphoisoforms of RNA polymerase II engage the Rtt103 termination factor in a structurally analogous manner.

Nemec, Corey M; Yang, Fan; Gilmore, Joshua M; Hintermair, Corinna; Ho, Yi-Hsuan; Tseng, Sandra C; Heidemann, Martin; Zhang, Ying; Florens, Laurence; Gasch, Audrey P; Eick, Dirk; Washburn, Michael P; Varani, Gabriele; Ansari, Aseem Z.

Proc Natl Acad Sci U S A ; 114(20): E3944-E3953, 2017 05 16.

Article in English | MEDLINE | ID: mdl-28465432

14.

Reprogramming cell fate with a genome-scale library of artificial transcription factors.

Eguchi, Asuka; Wleklinski, Matthew J; Spurgat, Mackenzie C; Heiderscheit, Evan A; Kropornicka, Anna S; Vu, Catherine K; Bhimsaria, Devesh; Swanson, Scott A; Stewart, Ron; Ramanathan, Parameswaran; Kamp, Timothy J; Slukvin, Igor; Thomson, James A; Dutton, James R; Ansari, Aseem Z.

Proc Natl Acad Sci U S A ; 113(51): E8257-E8266, 2016 12 20.

Article in English | MEDLINE | ID: mdl-27930301

15.

Synthetic genome readers target clustered binding sites across diverse chromatin states.

Erwin, Graham S; Grieshop, Matthew P; Bhimsaria, Devesh; Do, Truman J; Rodríguez-Martínez, José A; Mehta, Charu; Khanna, Kanika; Swanson, Scott A; Stewart, Ron; Thomson, James A; Ramanathan, Parameswaran; Ansari, Aseem Z.

Proc Natl Acad Sci U S A ; 113(47): E7418-E7427, 2016 11 22.

Article in English | MEDLINE | ID: mdl-27830652

16.

The conserved bromo-adjacent homology domain of yeast Orc1 functions in the selection of DNA replication origins within chromatin.

Müller, Philipp; Park, Sookhee; Shor, Erika; Huebert, Dana J; Warren, Christopher L; Ansari, Aseem Z; Weinreich, Michael; Eaton, Matthew L; MacAlpine, David M; Fox, Catherine A.

Genes Dev ; 24(13): 1418-33, 2010 Jul 01.

Article in English | MEDLINE | ID: mdl-20595233

17.

Regulator trafficking on bacterial transcription units in vivo.

Mooney, Rachel A; Davis, Sarah E; Peters, Jason M; Rowland, Jennifer L; Ansari, Aseem Z; Landick, Robert.

Mol Cell ; 33(1): 97-108, 2009 Jan 16.

Article in English | MEDLINE | ID: mdl-19150431

18.

TFIIH kinase places bivalent marks on the carboxy-terminal domain of RNA polymerase II.

Akhtar, Md Sohail; Heidemann, Martin; Tietjen, Joshua R; Zhang, David W; Chapman, Rob D; Eick, Dirk; Ansari, Aseem Z.

Mol Cell ; 34(3): 387-93, 2009 May 15.

Article in English | MEDLINE | ID: mdl-19450536

19.

A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters.

Badis, Gwenael; Chan, Esther T; van Bakel, Harm; Pena-Castillo, Lourdes; Tillo, Desiree; Tsui, Kyle; Carlson, Clayton D; Gossett, Andrea J; Hasinoff, Michael J; Warren, Christopher L; Gebbia, Marinella; Talukder, Shaheynoor; Yang, Ally; Mnaimneh, Sanie; Terterov, Dimitri; Coburn, David; Li Yeo, Ai; Yeo, Zhen Xuan; Clarke, Neil D; Lieb, Jason D; Ansari, Aseem Z; Nislow, Corey; Hughes, Timothy R.

Mol Cell ; 32(6): 878-87, 2008 Dec 26.

Article in English | MEDLINE | ID: mdl-19111667

20.

The bacterial response regulator ArcA uses a diverse binding site architecture to regulate carbon oxidation globally.

Park, Dan M; Akhtar, Md Sohail; Ansari, Aseem Z; Landick, Robert; Kiley, Patricia J.

PLoS Genet ; 9(10): e1003839, 2013.

Article in English | MEDLINE | ID: mdl-24146625

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