Search | Virtual Health Library

1.

Proteogenomic analysis of chemo-refractory high-grade serous ovarian cancer.

Chowdhury, Shrabanti; Kennedy, Jacob J; Ivey, Richard G; Murillo, Oscar D; Hosseini, Noshad; Song, Xiaoyu; Petralia, Francesca; Calinawan, Anna; Savage, Sara R; Berry, Anna B; Reva, Boris; Ozbek, Umut; Krek, Azra; Ma, Weiping; da Veiga Leprevost, Felipe; Ji, Jiayi; Yoo, Seungyeul; Lin, Chenwei; Voytovich, Uliana J; Huang, Yajue; Lee, Sun-Hee; Bergan, Lindsay; Lorentzen, Travis D; Mesri, Mehdi; Rodriguez, Henry; Hoofnagle, Andrew N; Herbert, Zachary T; Nesvizhskii, Alexey I; Zhang, Bing; Whiteaker, Jeffrey R; Fenyo, David; McKerrow, Wilson; Wang, Joshua; Schürer, Stephan C; Stathias, Vasileios; Chen, X Steven; Barcellos-Hoff, Mary Helen; Starr, Timothy K; Winterhoff, Boris J; Nelson, Andrew C; Mok, Samuel C; Kaufmann, Scott H; Drescher, Charles; Cieslik, Marcin; Wang, Pei; Birrer, Michael J; Paulovich, Amanda G.

Cell ; 186(16): 3476-3498.e35, 2023 08 03.

Article in English | MEDLINE | ID: mdl-37541199

2.

Proteogenomic analysis of chemo-refractory high-grade serous ovarian cancer.

Chowdhury, Shrabanti; Kennedy, Jacob J; Ivey, Richard G; Murillo, Oscar D; Hosseini, Noshad; Song, Xiaoyu; Petralia, Francesca; Calinawan, Anna; Savage, Sara R; Berry, Anna B; Reva, Boris; Ozbek, Umut; Krek, Azra; Ma, Weiping; da Veiga Leprevost, Felipe; Ji, Jiayi; Yoo, Seungyeul; Lin, Chenwei; Voytovich, Uliana J; Huang, Yajue; Lee, Sun-Hee; Bergan, Lindsay; Lorentzen, Travis D; Mesri, Mehdi; Rodriguez, Henry; Hoofnagle, Andrew N; Herbert, Zachary T; Nesvizhskii, Alexey I; Zhang, Bing; Whiteaker, Jeffrey R; Fenyo, David; McKerrow, Wilson; Wang, Joshua; Schürer, Stephan C; Stathias, Vasileios; Chen, X Steven; Barcellos-Hoff, Mary Helen; Starr, Timothy K; Winterhoff, Boris J; Nelson, Andrew C; Mok, Samuel C; Kaufmann, Scott H; Drescher, Charles; Cieslik, Marcin; Wang, Pei; Birrer, Michael J; Paulovich, Amanda G.

Cell ; 187(4): 1016, 2024 Feb 15.

Article in English | MEDLINE | ID: mdl-38364782

3.

The radiobiology of TGFß.

Barcellos-Hoff, Mary Helen.

Semin Cancer Biol ; 86(Pt 3): 857-867, 2022 11.

Article in English | MEDLINE | ID: mdl-35122974

4.

Subverting misconceptions about radiation therapy.

Formenti, Silvia C; Demaria, Sandra; Barcellos-Hoff, Mary Helen; McBride, William H.

Nat Immunol ; 17(4): 345, 2016 Apr.

Article in English | MEDLINE | ID: mdl-27002831

5.

Altered regulation of BRCA1 exon 11 splicing is associated with breast cancer risk in carriers of BRCA1 pathogenic variants.

Ruiz de Garibay, Gorka; Fernandez-Garcia, Ignacio; Mazoyer, Sylvie; Leme de Calais, Flavia; Ameri, Pietro; Vijayakumar, Sangeetha; Martinez-Ruiz, Haydeliz; Damiola, Francesca; Barjhoux, Laure; Thomassen, Mads; Andersen, Lars V B; Herranz, Carmen; Mateo, Francesca; Palomero, Luis; Espín, Roderic; Gómez, Antonio; García, Nadia; Jimenez, Daniel; Bonifaci, Núria; Extremera, Ana I; Castaño, Julio; Raya, Angel; Eyras, Eduardo; Puente, Xose S; Brunet, Joan; Lázaro, Conxi; Radice, Paolo; Barnes, Daniel R; Antoniou, Antonis C; Spurdle, Amanda B; de la Hoya, Miguel; Baralle, Diana; Barcellos-Hoff, Mary Helen; Pujana, Miquel A.

Hum Mutat ; 42(11): 1488-1502, 2021 11.

Article in English | MEDLINE | ID: mdl-34420246

6.

The Microenvironment of Lung Cancer and Therapeutic Implications.

Mittal, Vivek; El Rayes, Tina; Narula, Navneet; McGraw, Timothy E; Altorki, Nasser K; Barcellos-Hoff, Mary Helen.

Adv Exp Med Biol ; 890: 75-110, 2016.

Article in English | MEDLINE | ID: mdl-26703800

7.

In Memoriam - Zena Werb 1945-2020.

Barcellos-Hoff, Mary Helen; Weaver, Valerie M.

J Mammary Gland Biol Neoplasia ; 25(3): 179-180, 2020 09.

Article in English | MEDLINE | ID: mdl-32997280

8.

The effect of environmental chemicals on the tumor microenvironment.

Casey, Stephanie C; Vaccari, Monica; Al-Mulla, Fahd; Al-Temaimi, Rabeah; Amedei, Amedeo; Barcellos-Hoff, Mary Helen; Brown, Dustin G; Chapellier, Marion; Christopher, Joseph; Curran, Colleen S; Forte, Stefano; Hamid, Roslida A; Heneberg, Petr; Koch, Daniel C; Krishnakumar, P K; Laconi, Ezio; Maguer-Satta, Veronique; Marongiu, Fabio; Memeo, Lorenzo; Mondello, Chiara; Raju, Jayadev; Roman, Jesse; Roy, Rabindra; Ryan, Elizabeth P; Ryeom, Sandra; Salem, Hosni K; Scovassi, A Ivana; Singh, Neetu; Soucek, Laura; Vermeulen, Louis; Whitfield, Jonathan R; Woodrick, Jordan; Colacci, Annamaria; Bisson, William H; Felsher, Dean W.

Carcinogenesis ; 36 Suppl 1: S160-83, 2015 Jun.

Article in English | MEDLINE | ID: mdl-26106136

9.

Development of a novel multiplexed assay for quantification of transforming growth factor-ß (TGF-ß).

Pellicciotta, Ilenia; Marciscano, Ariel E; Hardee, Matthew E; Francis, Derek; Formenti, Silvia; Barcellos-Hoff, Mary Helen.

Growth Factors ; 33(2): 79-91, 2015 Apr.

Article in English | MEDLINE | ID: mdl-25586866

10.

Irradiation of juvenile, but not adult, mammary gland increases stem cell self-renewal and estrogen receptor negative tumors.

Tang, Jonathan; Fernandez-Garcia, Ignacio; Vijayakumar, Sangeetha; Martinez-Ruis, Haydeliz; Illa-Bochaca, Irineu; Nguyen, David H; Mao, Jian-Hua; Costes, Sylvain V; Barcellos-Hoff, Mary Helen.

Stem Cells ; 32(3): 649-61, 2014 Mar.

Article in English | MEDLINE | ID: mdl-24038768

11.

Radiation and the microenvironment - tumorigenesis and therapy.

Barcellos-Hoff, Mary Helen; Park, Catherine; Wright, Eric G.

Nat Rev Cancer ; 5(11): 867-75, 2005 Nov.

Article in English | MEDLINE | ID: mdl-16327765

12.

New biological insights on the link between radiation exposure and breast cancer risk.

Barcellos-Hoff, Mary Helen.

J Mammary Gland Biol Neoplasia ; 18(1): 3-13, 2013 Mar.

Article in English | MEDLINE | ID: mdl-23325014

13.

Lack of TGFß signaling competency predicts immune poor cancer conversion to immune rich and response to checkpoint blockade.

Moore, Jade; Gkantalis, Jim; Guix, Ines; Chou, William; Yuen, Kobe; Lazar, Ann A; Spitzer, Mathew; Combes, Alexis J; Barcellos-Hoff, Mary Helen.

bioRxiv ; 2024 May 21.

Article in English | MEDLINE | ID: mdl-38496519

14.

PLX038A, a long-acting SN-38, penetrates the blood-tumor-brain-barrier, accumulates and releases SN-38 in brain tumors to increase survival of tumor bearing mice.

Jung, Jinkyu; Schneider, Eric L; Zhang, Wei; Song, Hua; Zhang, Meili; Chou, William; Meher, Niranjan; VanBrocklin, Henry F; Barcellos-Hoff, Mary Helen; Ozawa, Tomoko; Gilbert, Mark R; Santi, Daniel V.

Sci Rep ; 14(1): 14175, 2024 06 19.

Article in English | MEDLINE | ID: mdl-38898077

15.

Molecular Pathways and Mechanisms of TGFß in Cancer Therapy.

Barcellos-Hoff, Mary Helen; Gulley, James L.

Clin Cancer Res ; 29(11): 2025-2033, 2023 06 01.

Article in English | MEDLINE | ID: mdl-36598437

16.

Monitoring TGFß signaling in irradiated tumors.

Ma, Lin; Gonzalez-Junca, Alba; Chou, William; Barcellos-Hoff, Mary Helen.

Methods Cell Biol ; 180: 49-67, 2023.

Article in English | MEDLINE | ID: mdl-37890932

17.

Updates on radiotherapy-immunotherapy combinations: Proceedings of 6^th annual ImmunoRad conference.

Gregucci, Fabiana; Spada, Sheila; Barcellos-Hoff, Mary Helen; Bhardwaj, Nina; Chan Wah Hak, Charleen; Fiorentino, Alba; Guha, Chandan; Guzman, Monica L; Harrington, Kevin; Herrera, Fernanda G; Honeychurch, Jamie; Hong, Theodore; Iturri, Lorea; Jaffee, Elisabeth; Karam, Sana D; Knott, Simon R V; Koumenis, Constantinos; Lyden, David; Marciscano, Ariel E; Melcher, Alan; Mondini, Michele; Mondino, Anna; Morris, Zachary S; Pitroda, Sean; Quezada, Sergio A; Santambrogio, Laura; Shiao, Stephen; Stagg, John; Telarovic, Irma; Timmerman, Robert; Vozenin, Marie-Catherine; Weichselbaum, Ralph; Welsh, James; Wilkins, Anna; Xu, Chris; Zappasodi, Roberta; Zou, Weiping; Bobard, Alexandre; Demaria, Sandra; Galluzzi, Lorenzo; Deutsch, Eric; Formenti, Silvia C.

Oncoimmunology ; 12(1): 2222560, 2023.

Article in English | MEDLINE | ID: mdl-37363104

18.

Consequences of epithelial or stromal TGFß1 depletion in the mammary gland.

Nguyen, David H; Martinez-Ruiz, Haydeliz; Barcellos-Hoff, Mary Helen.

J Mammary Gland Biol Neoplasia ; 16(2): 147-55, 2011 Jun.

Article in English | MEDLINE | ID: mdl-21590374

19.

Mammary Tumor-Derived Transplants as Breast Cancer Models to Evaluate Tumor-Immune Interactions and Therapeutic Responses.

Moore, Jade; Ma, Lin; Lazar, Ann A; Barcellos-Hoff, Mary Helen.

Cancer Res ; 82(3): 365-376, 2022 02 01.

Article in English | MEDLINE | ID: mdl-34903599

20.

Exploiting Canonical TGFß Signaling in Cancer Treatment.

Liu, Qi; Chen, Genwen; Moore, Jade; Guix, Ines; Placantonakis, Dimitris; Barcellos-Hoff, Mary Helen.

Mol Cancer Ther ; 21(1): 16-24, 2022 01.

Article in English | MEDLINE | ID: mdl-34670783

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Proteogenomic analysis of chemo-refractory high-grade serous ovarian cancer.

Proteogenomic analysis of chemo-refractory high-grade serous ovarian cancer.

The radiobiology of TGFß.

Subverting misconceptions about radiation therapy.

Altered regulation of BRCA1 exon 11 splicing is associated with breast cancer risk in carriers of BRCA1 pathogenic variants.

The Microenvironment of Lung Cancer and Therapeutic Implications.

In Memoriam - Zena Werb 1945-2020.

The effect of environmental chemicals on the tumor microenvironment.

Development of a novel multiplexed assay for quantification of transforming growth factor-ß (TGF-ß).

Irradiation of juvenile, but not adult, mammary gland increases stem cell self-renewal and estrogen receptor negative tumors.

Radiation and the microenvironment - tumorigenesis and therapy.

New biological insights on the link between radiation exposure and breast cancer risk.

Lack of TGFß signaling competency predicts immune poor cancer conversion to immune rich and response to checkpoint blockade.

PLX038A, a long-acting SN-38, penetrates the blood-tumor-brain-barrier, accumulates and releases SN-38 in brain tumors to increase survival of tumor bearing mice.

Molecular Pathways and Mechanisms of TGFß in Cancer Therapy.

Monitoring TGFß signaling in irradiated tumors.

Updates on radiotherapy-immunotherapy combinations: Proceedings of 6^th annual ImmunoRad conference.

Consequences of epithelial or stromal TGFß1 depletion in the mammary gland.

Mammary Tumor-Derived Transplants as Breast Cancer Models to Evaluate Tumor-Immune Interactions and Therapeutic Responses.

Exploiting Canonical TGFß Signaling in Cancer Treatment.