Search | Virtual Health Library

1.

Interrelated role of Klotho and calcium-sensing receptor in parathyroid hormone synthesis and parathyroid hyperplasia.

Fan, Yi; Liu, Weiqing; Bi, Ruiye; Densmore, Michael J; Sato, Tadatoshi; Mannstadt, Michael; Yuan, Quan; Zhou, Xuedong; Olauson, Hannes; Larsson, Tobias E; Toka, Hakan R; Pollak, Martin R; Brown, Edward M; Lanske, Beate.

Proc Natl Acad Sci U S A ; 115(16): E3749-E3758, 2018 04 17.

Article in English | MEDLINE | ID: mdl-29618612

2.

Calcium-Sensing Receptor Autoantibodies in Patients with Autoimmune Polyendocrine Syndrome Type 1: Epitopes, Specificity, Functional Affinity, IgG Subclass, and Effects on Receptor Activity.

Habibullah, Mahmoud; Porter, Julie A; Kluger, Nicolas; Ranki, Annamari; Krohn, Kai J E; Brandi, Maria L; Brown, Edward M; Weetman, Anthony P; Kemp, E Helen.

J Immunol ; 201(11): 3175-3183, 2018 12 01.

Article in English | MEDLINE | ID: mdl-30381479

3.

Immunosuppressive therapy of autoimmune hypoparathyroidism in a patient with activating autoantibodies against the calcium-sensing receptor.

Chamberlin, Mina; Kemp, E Helen; Weetman, Anthony P; Khadka, Bhupesh; Brown, Edward M.

Clin Endocrinol (Oxf) ; 90(1): 214-221, 2019 01.

Article in English | MEDLINE | ID: mdl-30358904

4.

François Leuret: the last moral therapist.

Brown, Edward M.

Hist Psychiatry ; 29(1): 38-48, 2018 Mar.

Article in English | MEDLINE | ID: mdl-29072855

5.

The calcium-sensing receptor: A promising target for prevention of colorectal cancer.

Aggarwal, Abhishek; Prinz-Wohlgenannt, Maximilian; Tennakoon, Samawansha; Höbaus, Julia; Boudot, Cedric; Mentaverri, Romuald; Brown, Edward M; Baumgartner-Parzer, Sabina; Kállay, Enikö.

Biochim Biophys Acta ; 1853(9): 2158-67, 2015 Sep.

Article in English | MEDLINE | ID: mdl-25701758

6.

Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.

O'Seaghdha, Conall M; Wu, Hongsheng; Yang, Qiong; Kapur, Karen; Guessous, Idris; Zuber, Annie Mercier; Köttgen, Anna; Stoudmann, Candice; Teumer, Alexander; Kutalik, Zoltán; Mangino, Massimo; Dehghan, Abbas; Zhang, Weihua; Eiriksdottir, Gudny; Li, Guo; Tanaka, Toshiko; Portas, Laura; Lopez, Lorna M; Hayward, Caroline; Lohman, Kurt; Matsuda, Koichi; Padmanabhan, Sandosh; Firsov, Dmitri; Sorice, Rossella; Ulivi, Sheila; Brockhaus, A Catharina; Kleber, Marcus E; Mahajan, Anubha; Ernst, Florian D; Gudnason, Vilmundur; Launer, Lenore J; Mace, Aurelien; Boerwinckle, Eric; Arking, Dan E; Tanikawa, Chizu; Nakamura, Yusuke; Brown, Morris J; Gaspoz, Jean-Michel; Theler, Jean-Marc; Siscovick, David S; Psaty, Bruce M; Bergmann, Sven; Vollenweider, Peter; Vitart, Veronique; Wright, Alan F; Zemunik, Tatijana; Boban, Mladen; Kolcic, Ivana; Navarro, Pau; Brown, Edward M.

PLoS Genet ; 9(9): e1003796, 2013.

Article in English | MEDLINE | ID: mdl-24068962

7.

Identification of an L-phenylalanine binding site enhancing the cooperative responses of the calcium-sensing receptor to calcium.

Zhang, Chen; Huang, Yun; Jiang, Yusheng; Mulpuri, Nagaraju; Wei, Ling; Hamelberg, Donald; Brown, Edward M; Yang, Jenny J.

J Biol Chem ; 289(8): 5296-309, 2014 Feb 21.

Article in English | MEDLINE | ID: mdl-24394414

8.

Direct determination of multiple ligand interactions with the extracellular domain of the calcium-sensing receptor.

Zhang, Chen; Zhuo, You; Moniz, Heather A; Wang, Shuo; Moremen, Kelley W; Prestegard, James H; Brown, Edward M; Yang, Jenny J.

J Biol Chem ; 289(48): 33529-42, 2014 Nov 28.

Article in English | MEDLINE | ID: mdl-25305020

9.

Extracellular calcium modulates actions of orthosteric and allosteric ligands on metabotropic glutamate receptor 1α.

Jiang, Jason Y; Nagaraju, Mulpuri; Meyer, Rebecca C; Zhang, Li; Hamelberg, Donald; Hall, Randy A; Brown, Edward M; Conn, P Jeffrey; Yang, Jenny J.

J Biol Chem ; 289(3): 1649-61, 2014 Jan 17.

Article in English | MEDLINE | ID: mdl-24280223

10.

The calcium-sensing receptor suppresses epithelial-to-mesenchymal transition and stem cell- like phenotype in the colon.

Aggarwal, Abhishek; Prinz-Wohlgenannt, Maximilian; Gröschel, Charlotte; Tennakoon, Samawansha; Meshcheryakova, Anastasia; Chang, Wenhan; Brown, Edward M; Mechtcheriakova, Diana; Kállay, Enikö.

Mol Cancer ; 14: 61, 2015 Mar 18.

Article in English | MEDLINE | ID: mdl-25879211

11.

Identification of 70 calcium-sensing receptor mutations in hyper- and hypo-calcaemic patients: evidence for clustering of extracellular domain mutations at calcium-binding sites.

Hannan, Fadil M; Nesbit, M Andrew; Zhang, Chen; Cranston, Treena; Curley, Alan J; Harding, Brian; Fratter, Carl; Rust, Nigel; Christie, Paul T; Turner, Jeremy J O; Lemos, Manuel C; Bowl, Michael R; Bouillon, Roger; Brain, Caroline; Bridges, Nicola; Burren, Christine; Connell, John M; Jung, Heike; Marks, Eileen; McCredie, David; Mughal, Zulf; Rodda, Christine; Tollefsen, Sherida; Brown, Edward M; Yang, Jenny J; Thakker, Rajesh V.

Hum Mol Genet ; 21(12): 2768-78, 2012 Jun 15.

Article in English | MEDLINE | ID: mdl-22422767

12.

The empirical foundations of telemedicine interventions for chronic disease management.

Bashshur, Rashid L; Shannon, Gary W; Smith, Brian R; Alverson, Dale C; Antoniotti, Nina; Barsan, William G; Bashshur, Noura; Brown, Edward M; Coye, Molly J; Doarn, Charles R; Ferguson, Stewart; Grigsby, Jim; Krupinski, Elizabeth A; Kvedar, Joseph C; Linkous, Jonathan; Merrell, Ronald C; Nesbitt, Thomas; Poropatich, Ronald; Rheuban, Karen S; Sanders, Jay H; Watson, Andrew R; Weinstein, Ronald S; Yellowlees, Peter.

Telemed J E Health ; 20(9): 769-800, 2014 Sep.

Article in English | MEDLINE | ID: mdl-24968105

13.

CaSR-mediated interactions between calcium and magnesium homeostasis in mice.

Quinn, Stephen J; Thomsen, Alex R B; Egbuna, Ogo; Pang, Jian; Baxi, Khanjan; Goltzman, David; Pollak, Martin; Brown, Edward M.

Am J Physiol Endocrinol Metab ; 304(7): E724-33, 2013 Apr 01.

Article in English | MEDLINE | ID: mdl-23360827

14.

Interactions between calcium and phosphorus in the regulation of the production of fibroblast growth factor 23 in vivo.

Quinn, Stephen J; Thomsen, Alex R B; Pang, Jian L; Kantham, Lakshmi; Bräuner-Osborne, Hans; Pollak, Martin; Goltzman, David; Brown, Edward M.

Am J Physiol Endocrinol Metab ; 304(3): E310-20, 2013 Feb 01.

Article in English | MEDLINE | ID: mdl-23233539

15.

Acquired hypocalciuric hypercalcemia in a patient with CKD.

Kuo, Elizabeth; Kemp, E Helen; Sandhu, Harpreet K; Brown, Edward M; Weetman, Anthony P; Huang, Chou-Long.

Am J Kidney Dis ; 62(6): 1151-4, 2013 Dec.

Article in English | MEDLINE | ID: mdl-23810542

16.

Parathyroid hormone ablation alters erythrocyte parameters that are rescued by calcium-sensing receptor gene deletion.

Romero, Jose R; Youte, Rodeler; Brown, Edward M; Pollak, Martin R; Goltzman, David; Karaplis, Andrew; Pong, Lie-Chin; Chien, Lawrence; Chattopadhyay, Naibedya; Rivera, Alicia.

Eur J Haematol ; 91(1): 37-45, 2013 Jul.

Article in English | MEDLINE | ID: mdl-23528155

17.

Deficiency of the calcium-sensing receptor in the kidney causes parathyroid hormone-independent hypocalciuria.

Toka, Hakan R; Al-Romaih, Khaldoun; Koshy, Jacob M; DiBartolo, Salvatore; Kos, Claudine H; Quinn, Stephen J; Curhan, Gary C; Mount, David B; Brown, Edward M; Pollak, Martin R.

J Am Soc Nephrol ; 23(11): 1879-90, 2012 Nov.

Article in English | MEDLINE | ID: mdl-22997254

18.

The Ontario Telemedicine Network: a case report.

Brown, Edward M.

Telemed J E Health ; 19(5): 373-6, 2013 May.

Article in English | MEDLINE | ID: mdl-23301768

19.

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells.

Nauli, Surya M; Alenghat, Francis J; Luo, Ying; Williams, Eric; Vassilev, Peter; Li, Xiaogang; Elia, Andrew E H; Lu, Weining; Brown, Edward M; Quinn, Stephen J; Ingber, Donald E; Zhou, Jing.

Nat Genet ; 33(2): 129-37, 2003 Feb.

Article in English | MEDLINE | ID: mdl-12514735

20.

The calcium-sensing receptor complements parathyroid hormone-induced bone turnover in discrete skeletal compartments in mice.

Xue, Yingben; Xiao, Yongjun; Liu, Jingning; Karaplis, Andrew C; Pollak, Martin R; Brown, Edward M; Miao, Dengshun; Goltzman, David.

Am J Physiol Endocrinol Metab ; 302(7): E841-51, 2012 Apr 01.

Article in English | MEDLINE | ID: mdl-22275754

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