Search | Virtual Health Library

1.

Base editing of organellar DNA with programmable deaminases.

Kim, Jin-Soo; Chen, Jia.

Nat Rev Mol Cell Biol ; 25(1): 34-45, 2024 Jan.

Article in English | MEDLINE | ID: mdl-37794167

2.

Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction.

Wells, Daniel K; van Buuren, Marit M; Dang, Kristen K; Hubbard-Lucey, Vanessa M; Sheehan, Kathleen C F; Campbell, Katie M; Lamb, Andrew; Ward, Jeffrey P; Sidney, John; Blazquez, Ana B; Rech, Andrew J; Zaretsky, Jesse M; Comin-Anduix, Begonya; Ng, Alphonsus H C; Chour, William; Yu, Thomas V; Rizvi, Hira; Chen, Jia M; Manning, Patrice; Steiner, Gabriela M; Doan, Xengie C; Merghoub, Taha; Guinney, Justin; Kolom, Adam; Selinsky, Cheryl; Ribas, Antoni; Hellmann, Matthew D; Hacohen, Nir; Sette, Alessandro; Heath, James R; Bhardwaj, Nina; Ramsdell, Fred; Schreiber, Robert D; Schumacher, Ton N; Kvistborg, Pia; Defranoux, Nadine A.

Cell ; 183(3): 818-834.e13, 2020 10 29.

Article in English | MEDLINE | ID: mdl-33038342

3.

One Prime for All Editing.

Yang, Li; Yang, Bei; Chen, Jia.

Cell ; 179(7): 1448-1450, 2019 Dec 12.

Article in English | MEDLINE | ID: mdl-31835025

4.

Pervasive Chromatin-RNA Binding Protein Interactions Enable RNA-Based Regulation of Transcription.

Xiao, Rui; Chen, Jia-Yu; Liang, Zhengyu; Luo, Daji; Chen, Geng; Lu, Zhi John; Chen, Yang; Zhou, Bing; Li, Hairi; Du, Xian; Yang, Yang; San, Mingkui; Wei, Xintao; Liu, Wen; Lécuyer, Eric; Graveley, Brenton R; Yeo, Gene W; Burge, Christopher B; Zhang, Michael Q; Zhou, Yu; Fu, Xiang-Dong.

Cell ; 178(1): 107-121.e18, 2019 06 27.

Article in English | MEDLINE | ID: mdl-31251911

5.

Ubiquiton-An inducible, linkage-specific polyubiquitylation tool.

Renz, Christian; Asimaki, Evrydiki; Meister, Cindy; Albanèse, Véronique; Petriukov, Kirill; Krapoth, Nils C; Wegmann, Sabrina; Wollscheid, Hans-Peter; Wong, Ronald P; Fulzele, Amitkumar; Chen, Jia-Xuan; Léon, Sébastien; Ulrich, Helle D.

Mol Cell ; 84(2): 386-400.e11, 2024 Jan 18.

Article in English | MEDLINE | ID: mdl-38103558

6.

K6-linked ubiquitylation marks formaldehyde-induced RNA-protein crosslinks for resolution.

Suryo Rahmanto, Aldwin; Blum, Christian J; Scalera, Claudia; Heidelberger, Jan B; Mesitov, Mikhail; Horn-Ghetko, Daniel; Gräf, Justus F; Mikicic, Ivan; Hobrecht, Rebecca; Orekhova, Anna; Ostermaier, Matthias; Ebersberger, Stefanie; Möckel, Martin M; Krapoth, Nils; Da Silva Fernandes, Nádia; Mizi, Athanasia; Zhu, Yajie; Chen, Jia-Xuan; Choudhary, Chunaram; Papantonis, Argyris; Ulrich, Helle D; Schulman, Brenda A; König, Julian; Beli, Petra.

Mol Cell ; 83(23): 4272-4289.e10, 2023 Dec 07.

Article in English | MEDLINE | ID: mdl-37951215

7.

Discrete RNA-DNA hybrid cleavage by the EXD2 exonuclease pinpoints two rate-limiting steps.

Jia, Xinshuo; Li, Yanan; Wang, Teng; Bi, Lulu; Guo, Lijuan; Chen, Ziting; Zhang, Xia; Ye, Shasha; Chen, Jia; Yang, Bei; Sun, Bo.

EMBO J ; 42(1): e111703, 2023 01 04.

Article in English | MEDLINE | ID: mdl-36326837

8.

Forces driving transposable element load variation during Arabidopsis range expansion.

Jiang, Juan; Xu, Yong-Chao; Zhang, Zhi-Qin; Chen, Jia-Fu; Niu, Xiao-Min; Hou, Xing-Hui; Li, Xin-Tong; Wang, Li; Zhang, Yong E; Ge, Song; Guo, Ya-Long.

Plant Cell ; 36(4): 840-862, 2024 Mar 29.

Article in English | MEDLINE | ID: mdl-38036296

9.

Engineering of NEMO as calcium indicators with large dynamics and high sensitivity.

Li, Jia; Shang, Ziwei; Chen, Jia-Hui; Gu, Wenjia; Yao, Li; Yang, Xin; Sun, Xiaowen; Wang, Liuqing; Wang, Tianlu; Liu, Siyao; Li, Jiajing; Hou, Tingting; Xing, Dajun; Gill, Donald L; Li, Jiejie; Wang, Shi-Qiang; Hou, Lijuan; Zhou, Yubin; Tang, Ai-Hui; Zhang, Xiaohui; Wang, Youjun.

Nat Methods ; 20(6): 918-924, 2023 Jun.

Article in English | MEDLINE | ID: mdl-37081094

10.

The AAA-ATPase Yta4/ATAD1 interacts with the mitochondrial divisome to inhibit mitochondrial fission.

He, Jiajia; Liu, Ke; Wu, Yifan; Zhao, Chenhui; Yan, Shuaijie; Chen, Jia-Hui; Hu, Lizhu; Wang, Dongmei; Zheng, Fan; Wei, Wenfan; Xu, Chao; Huang, Chengdong; Liu, Xing; Yao, Xuebiao; Ding, Lijun; Fang, Zhiyou; Tang, Ai-Hui; Fu, Chuanhai.

PLoS Biol ; 21(8): e3002247, 2023 08.

Article in English | MEDLINE | ID: mdl-37590302

11.

A large-scale binding and functional map of human RNA-binding proteins.

Van Nostrand, Eric L; Freese, Peter; Pratt, Gabriel A; Wang, Xiaofeng; Wei, Xintao; Xiao, Rui; Blue, Steven M; Chen, Jia-Yu; Cody, Neal A L; Dominguez, Daniel; Olson, Sara; Sundararaman, Balaji; Zhan, Lijun; Bazile, Cassandra; Bouvrette, Louis Philip Benoit; Bergalet, Julie; Duff, Michael O; Garcia, Keri E; Gelboin-Burkhart, Chelsea; Hochman, Myles; Lambert, Nicole J; Li, Hairi; McGurk, Michael P; Nguyen, Thai B; Palden, Tsultrim; Rabano, Ines; Sathe, Shashank; Stanton, Rebecca; Su, Amanda; Wang, Ruth; Yee, Brian A; Zhou, Bing; Louie, Ashley L; Aigner, Stefan; Fu, Xiang-Dong; Lécuyer, Eric; Burge, Christopher B; Graveley, Brenton R; Yeo, Gene W.

Nature ; 583(7818): 711-719, 2020 07.

Article in English | MEDLINE | ID: mdl-32728246

12.

Fluctuations in p53 Signaling Allow Escape from Cell-Cycle Arrest.

Reyes, José; Chen, Jia-Yun; Stewart-Ornstein, Jacob; Karhohs, Kyle W; Mock, Caroline S; Lahav, Galit.

Mol Cell ; 71(4): 581-591.e5, 2018 08 16.

Article in English | MEDLINE | ID: mdl-30057196

13.

The Augmented R-Loop Is a Unifying Mechanism for Myelodysplastic Syndromes Induced by High-Risk Splicing Factor Mutations.

Chen, Liang; Chen, Jia-Yu; Huang, Yi-Jou; Gu, Ying; Qiu, Jinsong; Qian, Hao; Shao, Changwei; Zhang, Xuan; Hu, Jing; Li, Hairi; He, Shunmin; Zhou, Yu; Abdel-Wahab, Omar; Zhang, Dong-Er; Fu, Xiang-Dong.

Mol Cell ; 69(3): 412-425.e6, 2018 02 01.

Article in English | MEDLINE | ID: mdl-29395063

14.

The p21CIP1-CDK4-DREAM axis is a master regulator of genotoxic stress-induced cellular senescence.

Schmidt, Ariane; Allmann, Sebastian; Schwarzenbach, Christian; Snyder, Petra; Chen, Jia-Xuan; Nagel, Georg; Schöneis, Anna; Rasenberger, Birgit; Beli, Petra; Loewer, Alexander; Hofmann, Thomas G; Tomicic, Maja T; Christmann, Markus.

Nucleic Acids Res ; 2024 May 23.

Article in English | MEDLINE | ID: mdl-38783095

15.

Low-sugar universal mRNA vaccine against coronavirus variants with deletion of glycosites in the S2 or stem of SARS-CoV-2 spike messenger RNA (mRNA).

Cheng, Cheng-Wei; Wu, Chung-Yi; Wang, Szu-Wen; Chen, Jia-Yan; Kung, Chih-Chuan; Liao, Kuo-Shiang; Wong, Chi-Huey.

Proc Natl Acad Sci U S A ; 120(49): e2314392120, 2023 Dec 05.

Article in English | MEDLINE | ID: mdl-38011546

16.

Apical-basal polarity in the gut.

Thottacherry, Joseph Jose; Chen, Jia; Johnston, Daniel St.

Semin Cell Dev Biol ; 150-151: 15-22, 2023 12.

Article in English | MEDLINE | ID: mdl-36670034

17.

Nuclear modifier YARS2 allele correction restored retinal ganglion cells-specific deficiencies in Leber's hereditary optic neuropathy.

Chen, Jia-Rong; Chen, Chao; Chen, Jie; Ji, Yanchun; Lian, Yanna; Zhang, Juanjuan; Yu, Jialing; Li, Xiang-Yao; Qu, Jia; Guan, Min-Xin.

Hum Mol Genet ; 32(9): 1539-1551, 2023 04 20.

Article in English | MEDLINE | ID: mdl-36611011

18.

Antibody-free profiling of transcription factor occupancy during early embryogenesis by FitCUT&RUN.

Wang, Xiangxiu; Wang, Wen; Wang, Yiman; Chen, Jia; Liu, Guifen; Zhang, Yong.

Genome Res ; 32(2): 378-388, 2022 02.

Article in English | MEDLINE | ID: mdl-34965941

19.

Short human eccDNAs are predictable from sequences.

Chang, Kai-Li; Chen, Jia-Hong; Lin, Tzu-Chieh; Leu, Jun-Yi; Kao, Cheng-Fu; Wong, Jin Yung; Tsai, Huai-Kuang.

Brief Bioinform ; 24(3)2023 05 19.

Article in English | MEDLINE | ID: mdl-37088981

20.

The OTUD1-Notch2-ICD axis orchestrates allogeneic T cell-mediated graft-versus-host disease.

Cheng, Qiao; Wang, Dong; Lai, Xiaoxuan; Liu, Yin; Zuo, Yibo; Zhang, Wenli; Lei, Lei; Chen, Jia; Liu, Hong; Wang, Ying; Liu, Haiyan; Zheng, Hui; Wu, Depei; Xu, Yang.

Blood ; 141(12): 1474-1488, 2023 03 23.

Article in English | MEDLINE | ID: mdl-36574342

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