A systematic review of different jump-landing variables in relation to injuries.

AIM: Injuries of the lower extremity tend to be associated with jump-landing movements. This review provides an overview of the kinematic variables and malalignments during jump-landing, which could be attributed to overuse or acute injury occurrence. METHODS: We searched ISI Web of Knowledge, SPORTDiscus, PubMed, EMBASE and SCOPUS for all studies, published before October 2012, which looked at the relation between kinematic risk factors and malalignments of jump-landing and injuries. An article was included 1) if the article was an observational, retrospective or prospective study; 2) if the article investigated the relationship between injuries and the visible and easily measurable kinematic variables or malalignments of the jump-landing technique; 3) if the article met a predefined quality cut-off score. RESULTS: Ten studies met all inclusion criteria. Literature shows that several kinematic factors are related to lower acute and overuse injuries. CONCLUSION: A stiffer jump-landing technique is a risk factor in the development of overuse injuries and acute injuries. This is caused by less active motion in the lower extremity joints and by the increased valgus position of the knee during the jump-landing maneuver which creates an unfavorable alignment of the lower extremity. A valgus position of the knee during landing was also a predictor of acute lower extremity injuries. Future intervention programs should focus on the jump-landing technique and the performance of the athlete.

Injury rate and socioeconomic costs resulting from sports injuries in Flanders: data derived from sports insurance statistics 2003.

OBJECTIVE: This study determines the injury rate (%) and the associated direct medical and indirect costs of sports injuries in Flanders. SETTING: Epidemiological cohort designs and a human capital method were set up to measure respectively the medical direct and indirect cost of sports injuries. PARTICIPANTS: 72 out of 82 Flemish sports federations participated. INTERVENTION: Insurance statistics from 2003 were used to determine the overall rate of injury and injury localisations. Using these data, the medical direct cost and the impact sports injuries have on indirect costs were estimated. The indirect costs were determined by multiplying the days of absence from work with the daily cost resulting from a loss of production, being 200 euros. MAIN OUTCOME: The total direct medical cost extrapolated for the Flemish sports participants was 15,027,423 euros, which amounted to 0.07% to 0.08% of the total budget spent on healthcare. The indirect cost extrapolated for the Flemish sports participants was 111,420,813 euros, which is about 3.4% of the costs arising from absenteeism from work. RESULTS: Of the 14 in-depth analysed sports, the rate of injury was highest in European team handball (8.96%; 95% confidence interval (CI) 8.95-8.96) and lowest in swimming (0.62%; 95% CI 0.62-0.62). The highest direct medical cost was found for anterior cruciate ligament (ACL) injuries (1358 euros per injury) and the lowest for foot injuries (52 euros per injury). CONCLUSION: The costs calculated in this study could become critical statistics in medical care debates. Data obtained here will enable a cost-benefit analysis of the impact of preventive measures to be made.

Low-back problems in recreational self-contained underwater breathing apparatus divers: prevalence and specific risk factors.

Low-back problems (LBP) are one of the most common musculoskeletal disorders in the general population, with reported lifetime prevalences of 50% to 80%. Also, certain sports participants (e.g. gymnasts, alpine skiers, runners) are at risk of LBP and its repercussions. This epidemiological study was undertaken to examine the lifetime and 1-year prevalence of LBP among recreational Flemish self-contained breathing apparatus (scuba) divers and to identify general and sport-specific risk factors associated with the occurrence of LBP. A retrospective self-assessment questionnaire was developed and assessed for validity and reliability, to gather data concerning demographics, LBP prevalence and associated risk factors and injuries among active scuba divers. A total of 181 recreational scuba divers (men: n = 138, mean age 40.3 +/- 12.8 years; women: n = 43, mean age 35.0 +/- 10.9 years) from 10 randomly selected internationally recognised scuba diving clubs participated in the study. Lifetime and 1-year prevalence of LBP among recreational Flemish scuba divers were 55.8% and 50.3%, respectively. General risk factors for LBP were found to include prior history of LBP, structural abnormalities, heavy workload, pregnancy and parturition, general fatigue and bending forwards and backwards. Scuba divers suffering from LBP generally had a significantly higher dive certificate than those without LBP (p = 0.007). Symptomatic scuba divers also used significantly more weights on their weight belts during indoor training (p = 0.003) and during outdoor dives with a dry suit (p = 0.044) as compared to asymptomatic scuba divers. In scuba diving, reliable sport-specific risk factors for LBP were found to be scarce. Further biomechanical research is required to point out whether or not scuba diving characteristics actually contribute to LBP.

Phase I clinical study of 9-hydroxy-2N-methyl-ellipticinium acetate (NSC-264137) administered on a 5-day i.v. schedule.

Twenty-three patients with advanced solid tumors received 9-hydroxy-2N-methyl-ellipticinium acetate at a single daily i.v. dose of 15-80 mg/m2 for 5 consecutive days, repeated every 3 weeks. One partial and one minor response were achieved in two patients with breast cancer. Dryness of the mouth was dose-related and dose-limiting. Local phlebitis was also dose-related and frequently severe at the highest dose levels. Other non-hematologic toxic effects were essentially mild to moderate and included nausea, vomiting, diarrhea, stomatitis, fever, weakness, transient renal and hepatic impairment, alopecia and chest pain. Minimal myelosuppression was encountered. It appears that 60 mg/m2/day is the maximum tolerated dose with a five-day schedule. According to our findings, this schedule does not seem to offer any advantage over the previously tested weekly administrations.