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1.
Emerg Infect Dis ; 22(12): 2137-2141, 2016 12.
Article in English | MEDLINE | ID: mdl-27584733

ABSTRACT

Highly pathogenic avian influenza A(H5N1), clade 2.3.2.1a, with an H9-like polymerase basic protein 1 gene, isolated in Bhutan in 2012, replicated faster in vitro than its H5N1 parental genotype and was transmitted more efficiently in a chicken model. These properties likely help limit/eradicate outbreaks, combined with strict control measures.


Subject(s)
Genotype , Influenza A Virus, H5N1 Subtype/classification , Influenza A Virus, H5N1 Subtype/genetics , Influenza in Birds/epidemiology , Influenza in Birds/virology , Poultry/virology , Reassortant Viruses/genetics , Animals , Bhutan/epidemiology , Disease Outbreaks , Geography, Medical , Humans , Influenza, Human/epidemiology , Phylogeny , Risk
2.
Emerg Infect Dis ; 20(9): 1524-6, 2014 Sep.
Article in English | MEDLINE | ID: mdl-25147965

ABSTRACT

In 2010, we investigated anthrax outbreak in Bhutan. A total of 43 domestic animals died, and cutaneous anthrax developed in 9 persons, and 1 died. All affected persons had contact with the carcasses of infected animals. Comprehensive preparedness and response guidelines are needed to increase public awareness of anthrax in Bhutan.


Subject(s)
Anthrax/epidemiology , Anthrax/prevention & control , Disease Outbreaks , Animals , Animals, Domestic , Anthrax/diagnosis , Anthrax/transmission , Bacillus anthracis/classification , Bacillus anthracis/genetics , Bhutan/epidemiology , Female , Genotype , Humans , Male , Multilocus Sequence Typing , Risk Factors , Skin/microbiology , Skin/pathology
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