Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 22
Filter
1.
Vet Comp Orthop Traumatol ; 23(5): 318-25, 2010.
Article in English | MEDLINE | ID: mdl-20740257

ABSTRACT

OBJECTIVES: To determine the clinical effects of juvenile pubic symphysiodesis (JPS) treatment in hip dysplasia-prone puppies with comparison to similar untreated control puppies. DESIGN: Controlled clinical case study. ANIMALS: Thirty-nine dysplastic puppies, of which six were part of the control group, with a positive Ortolani or hip distraction index (DI)≥0.40. PROCEDURES: The following eight clinical tests were evaluated preoperatively, and at one and two years postoperatively: Ortolani, hip reduction angle (HRA), gait evaluation, osteoarthritis, hip pain, and three Norberg angles (angle-extended mode [N-OFA], angle-compression mode [N-COM], and angle-distracted mode [N-DIS]). Juvenile pubic fusion (JPS) was performed by unipolar electro-cautery at 12 to 24 weeks of age; the control puppies received a sham operation. RESULTS: For the JPS puppies, the mean osteoarthritis level did not significantly increase (11%). There was a 74% reversal of preoperative positive Ortolani signs. Hip reduction angle, DI and N-DIS also improved significantly. Only N-DIS fully detected Norberg angle laxity. Within the control group, osteoarthritis increased significantly (55%) with no improvement in Ortolani incidence, N-OFA or N-COM angles. A decrease in HRA and DI was associated with increased osteoarthritis levels. Signs of hip pain increased by 33%, which was not significant. Dogs with initial severe hip laxity (DI≥0.70) experienced progressive osteoarthritis. CONCLUSIONS AND CLINICAL RELEVANCE: In JPS dogs with preoperative mild to moderate hip laxity (DI = 0.40-0.69), insignificant osteoarthritis occurred at two years. Juvenile pubic symphysiodesis surgery also improved other clinical criteria (Ortolani, HRA, hip pain, N-DIS). Osteoarthritis was generally not prevented by JPS in dogs with initial severely lax hips (DI≥0.70). Juvenile pubic symphysiodesis surgery at 12 to 24 weeks of age was an effective and safe pre-emptive bilateral treatment for mild to moderate hip dysplasia.


Subject(s)
Hip Dysplasia, Canine/surgery , Animals , Arthrodesis/methods , Arthrodesis/veterinary , Dog Diseases/epidemiology , Dogs , Follow-Up Studies , Gait/physiology , Hip Joint/surgery , Osteoarthritis/epidemiology , Osteoarthritis/veterinary , Pain, Postoperative/epidemiology , Pain, Postoperative/veterinary , Pubic Symphysis/surgery , Time Factors
2.
Vet Comp Orthop Traumatol ; 23(5): 306-17, 2010.
Article in English | MEDLINE | ID: mdl-20740258

ABSTRACT

OBJECTIVES: To measure one and two year effects of juvenile pubic symphysiodesis (JPS) in puppies defined as 'at-risk' for canine hip dysplasia (CHD) using the following objective hip conformation criteria: Acetabular angle (AA), dorsal acetabular rim angle (DARA) and hip laxity (PennHIP© distraction index (DI). DESIGN: Controlled clinical case study. ANIMALS: Thirty-nine dysplastic puppies (six controls). PROCEDURES: The dogs were anaesthetised and acetabular angle, DARA, and DI values were obtained by computed tomography and radiography preoperatively. Electro-cautery fusion of the pubic symphysis was performed between 12 - 24 weeks of age. The imaging was repeated at one and two years of age. RESULTS: Significant hip improvements were seen at the two-year follow-up appointments for: AA (JPS dogs 31% increase, control 3%), DARA (JPS 38% decrease, control 15%) and DI (JPS 41% decrease in laxity, controls 20%) for all postoperative versus preoperative values. Pubic fusion occurred with minor morbidity. CONCLUSION: Juvenile pubic symphysiodesis resulted in significant improvements in hip conformation (AA and DARA), especially in mild to moderately lax hips (DI = 0.40-0.69). Most dogs with DI≥0.70 increased in osteoarthritis grade by two years of age. CLINICAL RELEVANCE: Juvenile pubic symphysiodesis surgery at 12-24 weeks of age significantly improved hip conformation and decreased laxity in at-risk CHD dogs. Early-age (12 to 16 week) recognition of hip laxity offered greater JPS benefits than surgery performed at 19- to 24-weeks-old. Dogs with severe laxity (DI≥0.70) continued to increase in osteoarthritis. An early (12-16 weeks) positive laxity test (Ortolani) should alert one to obtain objective laxity determinations (PennHIP© DI).


Subject(s)
Hip Dysplasia, Canine/surgery , Pubic Symphysis/surgery , Acetabulum/diagnostic imaging , Age of Onset , Animals , Body Weight , Dogs , Follow-Up Studies , Hip Dysplasia, Canine/diagnosis , Hip Dysplasia, Canine/diagnostic imaging , Osteoarthritis/diagnostic imaging , Osteoarthritis/surgery , Osteoarthritis/veterinary , Patient Selection , Pelvic Bones/diagnostic imaging , Pelvic Bones/surgery , Physical Examination , Postoperative Care/veterinary , Pubic Bone/diagnostic imaging , Pubic Bone/surgery , Pubic Symphysis/diagnostic imaging , Range of Motion, Articular , Tomography, X-Ray Computed/veterinary , Treatment Outcome
3.
Undersea Hyperb Med ; 35(1): 61-7, 2008.
Article in English | MEDLINE | ID: mdl-18351128

ABSTRACT

Prolonged exposure of humans and animals to increased pressure as in a disabled submarine (DISSUB) can saturate the body's tissues with dissolved N2 as compressed air is breathed. Decompression-induced bubble formation in the long bone marrow cavity may lead to a bone compartment syndrome resulting in bone ischemia and necrosis. We tested oxygen pre-breathing prior to decompression in sheep to assess the effect upon dysbaric osteonecrosis (DON) induction in a DISSUB simulation experiment. A total of sixteen adult female sheep were used throughout the experiment. Four sheep were used as controls without oxygen pre-breathing. All sheep (99 +/- 14 kg SD) underwent dry chamber air exposure at 60 fsw (2.79 atm abs) (.2827 MPa) for 24 h followed by oxygen (88-92%) pre-breathing (15-min, 1-h, and 2-h and air for control) before "dropout" decompression at 30 fsw/min (0.91 atm/min). 99mTc-methylene diphosphonate (MDP) bone scans of the distal (radii and tibiae) long bones were used to detect "hot spots" of remodeling suggestive of DON lesions. Alizarin complexone fluorochrome was injected to visualize sites of metabolic activity indicating DON repair of both the proximal and distal long bones (radii, tibiae, femora, and humeri). Our findings showed that the amount of alizarin complexone deposition and bone scan uptake was greater in sheep with shorter oxygen pre-breathing times than those undergoing longer pre-breathing dives (p = 0.0056 and p = 0.001, for one and two hour pre-breathes respectively). Proximal limb bones (femur, humerus) displayed less alizarin complexone deposition than the distal radius and tibia (p < 0.0001).


Subject(s)
Decompression Sickness/prevention & control , Osteonecrosis/prevention & control , Oxygen Inhalation Therapy/methods , Analysis of Variance , Animals , Anthraquinones , Bone Remodeling , Bone Resorption/diagnostic imaging , Decompression Sickness/complications , Female , Femur/diagnostic imaging , Humerus/diagnostic imaging , Osteonecrosis/diagnostic imaging , Osteonecrosis/etiology , Radionuclide Imaging , Radiopharmaceuticals , Radius/diagnostic imaging , Sheep , Technetium Tc 99m Medronate , Tibia/diagnostic imaging
4.
J Orthop Res ; 6(5): 721-9, 1988.
Article in English | MEDLINE | ID: mdl-3404329

ABSTRACT

The use of an internal fixation plate in the presence of a bone defect was studied using a theoretical model of an idealized long bone having a circular cross section and loaded using a combination of axial and bending loads. The analysis showed that the "bending-open" loading mode does not occur if, in the normal unplated bone, the line of action of the resultant axial load passes within the outer cortex at the location where the plate is to be applied. In this situation the fracture will deform in a "bending-closed" mode regardless of whether the plate is attached to the tension or the compression side. If bony contact cannot be achieved, lower plate stress is always encountered when the plate is attached to the compression side instead of the tension side. In vivo verification of the model was addressed in a pilot experiment using instrumented metal plates applied bilaterally to the femora of one dog. Bilateral bone defects were created in the midfemoral canine diaphysis. On one leg the plate was applied to the lateral aspect ("tension" side), and on the other leg the plate was applied to the medial aspect ("compression" side). The plate attached to the lateral aspect deformed plastically in the bending-closed mode. The contralateral plate that was attached to the medial aspect (compression side) of the femur did not show signs of plastic deformation. Furthermore, the plate strains were lower in the plate attached to the medial aspect than those in the plate attached to the lateral aspect.(ABSTRACT TRUNCATED AT 250 WORDS)


Subject(s)
Bone Plates , Fracture Fixation, Internal , Animals , Biomechanical Phenomena , Dogs , Femoral Fractures/diagnostic imaging , Femoral Fractures/etiology , Femoral Fractures/surgery , Mathematics , Models, Biological , Radiography
5.
J Am Vet Med Assoc ; 197(3): 383-8, 1990 Aug 01.
Article in English | MEDLINE | ID: mdl-2118129

ABSTRACT

Five cases involving female Doberman Pinschers, each with a mass composed of osseous, chondrous, or fibrous tissue, or a combination thereof, formed in or around the muscles of the hip, were reviewed. In each dog, the mass severely limited the coxofemoral joint range or motion, especially when the joint was extended. Surgical debulking resulted in a favorable outcome. All dogs tested had plasma concentrations of von Willebrand factor antigen below established normal limits. We believe that the low concentrations of von Willebrand factor antigen commonly found in Doberman Pinschers may predispose them to the development of this condition and its resulting pelvic limb lameness, presumably because of increased risk of microvascular bleeding. This association is presumptive because 2 dogs in our study had a history of excessive bleeding either before or after being treated for the hip condition. Trauma was associated in 2 cases. All 5 dogs, however, bled more than usual during the curative surgery. These 5 cases, plus additional reported cases, confirm this syndrome, which warrants recognition. The name von Willebrand heterotopic osteochondrofibrosis of Doberman Pinschers was selected because it identified the basic features of the syndrome.


Subject(s)
Dog Diseases , Lameness, Animal , Osteochondrodysplasias/veterinary , von Willebrand Diseases/veterinary , Animals , Breeding , Dogs , Female , Fibrosis , Hip , Ossification, Heterotopic/veterinary , Retrospective Studies , Syndrome
6.
J Am Vet Med Assoc ; 195(7): 951-3, 1989 Oct 01.
Article in English | MEDLINE | ID: mdl-2793577

ABSTRACT

Two dogs with clinical signs of polyarthritis developed rheumatoid arthritis subsequent to Borrelia burgdorferi infection. In both dogs, the diagnosis of B burgdorferi infection was based on clinical signs of disease and high serum B burgdorferi titer. After antibiotic administration, both dogs had decreased B burgdorferi titer, but clinical response was temporary or was lacking. The dogs subsequently were rheumatoid factor-positive (antinuclear antibody- and anti-globulin-negative) and responded to anti-inflammatory drug administration. Development of rheumatoid arthritis in both dogs after B burgdorferi infection implicates the Borrelia organism as an infective agent leading to the development of rheumatoid arthritis in dogs. Dogs with clinical signs suggestive of B burgdorferi infection should have antiglobulin, anti-nuclear antibody rheumatoid factor, and B burgdorferi tests performed to aid definitive diagnosis.


Subject(s)
Arthritis, Rheumatoid/veterinary , Dog Diseases/etiology , Lyme Disease/veterinary , Animals , Antibodies, Bacterial/analysis , Arthritis, Rheumatoid/diagnosis , Arthritis, Rheumatoid/etiology , Borrelia burgdorferi Group/immunology , Diagnosis, Differential , Dog Diseases/diagnosis , Dogs , Female , Lameness, Animal/diagnosis , Lameness, Animal/etiology , Lyme Disease/complications , Lyme Disease/diagnosis , Male , Rheumatoid Factor/analysis
7.
J Am Vet Med Assoc ; 214(1): 59-66, 1999 Jan 01.
Article in English | MEDLINE | ID: mdl-9887941

ABSTRACT

OBJECTIVE: To determine results of using interlocking nails (IN) for fixation of diaphyseal long bone fractures in dogs. DESIGN: Multi-center prospective clinical trial. ANIMALS: 134 dogs with diaphyseal fractures of the femur (n = 92), tibia (23), or humerus (19); 11 had previous unsuccessful treatments, and 103 had comminuted fractures of which 70 were classified as unstable. PROCEDURE: All fractures were stabilized with 6- or 8-mm-diameter IN with 3.5- or 4.5-mm screws, respectively. Cerclage wires and an autogenous bone graft were used at the surgeon's discretion. Participating surgeons provided information on age, sex, weight, and breed of the dog, details of the surgery, details of any intra- or postoperative complications, fracture healing time, and limb function. RESULTS: Eight dogs were lost to follow-up evaluation. In 105 of the remaining 126 dogs (83%), fractures healed without complications. For these 105 dogs, limb function was excellent (n = 90), good (12), fair (2), and poor (1). Complications developed for 21 dogs (17%); limb function after additional treatment was excellent (n = 10), good (2), fair (5), poor (1), or unreported (3). Interlocking nails broke in 9 dogs; breakage was attributed to fatigue failure because of use of too small an IN or because of insertion of the IN so that a screw hole was positioned at the fracture site. CLINICAL IMPLICATIONS: The high success rate and low complication rate suggest that IN can be used to stabilize diaphyseal fractures in dogs. Good technique is necessary for optimal results.


Subject(s)
Dogs/injuries , Femoral Fractures/veterinary , Fracture Fixation, Intramedullary/veterinary , Humeral Fractures/veterinary , Tibial Fractures/veterinary , Animals , Bone Nails/veterinary , Bone Screws/veterinary , Bone Transplantation/veterinary , Bone Wires/veterinary , Dogs/surgery , Femoral Fractures/surgery , Follow-Up Studies , Fracture Healing , Fractures, Comminuted/surgery , Fractures, Comminuted/veterinary , Humeral Fractures/surgery , Prospective Studies , Tibial Fractures/surgery , Treatment Failure , Treatment Outcome
8.
J Small Anim Pract ; 36(8): 360-7, 1995 Aug.
Article in English | MEDLINE | ID: mdl-8558868

ABSTRACT

Neurological improvement after decompressive surgery, without routine therapeutic or prophylactic disc fenestration, was evaluated retrospectively in a consecutive series of 93 dachshunds with thoracolumbar disc extrusion. In 24 per cent of procedures, deep pain sensation was not elicited in at least one hind paw before surgery. Median neurological status one to seven days after surgery, at the time of discharge, was significantly improved after hemilaminectomy compared with dorsal laminectomy (P < 0.05). After hemilaminectomy, deep pain sensation was not elicited in one or both hind paws of 8 per cent of dogs in which pain sensation was elicited before surgery, compared with 21 per cent after dorsal laminectomy (P > 0.05). Improvement in neurological grade at follow-up examination two to 12 weeks after hemilaminectomy was not significantly different compared with dorsal laminectomy (P > 0.05). Of dogs which were unable to walk before surgery, 83 per cent regained the ability to walk after hemilaminectomy, compared with 74 per cent after dorsal laminectomy (P > 0.05). In both groups, 50 per cent of dogs in which deep pain sensation was abnormal before surgery eventually regained the ability to walk after surgery (P = 1). One to two years after the first operation, a second laminectomy was performed in only 5 per cent of dogs because of extrusion of a different intervertebral disc which had not been fenestrated.


Subject(s)
Dog Diseases/surgery , Intervertebral Disc Displacement/veterinary , Laminectomy/veterinary , Lumbar Vertebrae , Thoracic Vertebrae , Animals , Behavior, Animal/physiology , Dog Diseases/diagnostic imaging , Dogs , Female , Follow-Up Studies , Intervertebral Disc Displacement/diagnostic imaging , Intervertebral Disc Displacement/surgery , Laminectomy/methods , Male , Neurologic Examination/veterinary , Radiography , Retrospective Studies
11.
Vet Radiol Ultrasound ; 41(6): 484-90, 2000.
Article in English | MEDLINE | ID: mdl-11130786

ABSTRACT

Hip joint laxity was evaluated in Golden Retriever (n = 60), Labrador Retriever (n = 23), and Labrador/Golden Retriever mix (n = 24) puppies. Ortolani and Bardens maneuvers, four radiographic measurement indices and three dynamic ultrasonographic measurements were used. Each puppy was evaluated twice; at 6.5 to 9 and 43 to 79 weeks of age. These nine methods were compared for accuracy in predicting the development of canine hip dysplasia with or without degenerative joint disease by a median age of 16 months. The Bardens maneuver was a significant predictor of canine hip dysplasia/+/-degenerative joint disease for Golden Retriever puppies, however, it was not a reliable predictor for the other two breeds. Norberg angle measurements taken with femurs in a neutral position with hips distracted (PennHip position) was a significant predictor of degenerative joint disease in two breeds, but not in Golden Retriever puppies. Ultrasound measurement was a reliable predictor of hip canine hip dysplasia/+/-degenerative joint disease for Labrador/Golden Retriever mix puppies, but was not reliable for the other two breeds. Palpation, radiographic, and ultrasonographic methods of evaluating hip joint laxity in puppies at 6.5 to 9 weeks of age were not consistently reliable for all three breeds in predicting hip dysplasia with or without degenerative joint disease at one year of age. A strong association was found between Norberg angle and degenerative joint disease occurrence, as well as between distraction index (PennHip) and degenerative joint disease occurrence when measured at 52 to 79 weeks of age, but not when measured at 6.5 to 9 weeks of age in these breeds. These results emphasize the difficulty of early detection of mild hip dysplasia in the dog.


Subject(s)
Hip Dysplasia, Canine/diagnosis , Palpation/veterinary , Radiography/veterinary , Ultrasonography/veterinary , Animals , Animals, Newborn , Breeding , Dogs , Hip Dysplasia, Canine/diagnostic imaging , Predictive Value of Tests
12.
Skeletal Radiol ; 22(2): 146-9, 1993.
Article in English | MEDLINE | ID: mdl-8438186

ABSTRACT

A young dog was found to have an osteosarcoma of the proximal femur containing a radiologically evident sequestrum of dead bone. Although the tumor was extensive, the plain films were most remarkable for the presence of a sequestrum. MR scans revealed the extent of the lesion, with low signal throughout the lesion consistent with the heavily calcified tumor and central avascular bone. At the 1-year follow-up, lung metastases had developed, but the dog appeared well.


Subject(s)
Bone Neoplasms/veterinary , Dog Diseases/diagnostic imaging , Femur/diagnostic imaging , Osteonecrosis/veterinary , Osteosarcoma/veterinary , Animals , Bone Neoplasms/diagnostic imaging , Bone Neoplasms/pathology , Dog Diseases/pathology , Dogs , Female , Femur/pathology , Magnetic Resonance Imaging/veterinary , Osteonecrosis/diagnostic imaging , Osteonecrosis/pathology , Osteosarcoma/diagnostic imaging , Osteosarcoma/pathology , Radiography
13.
Vet Surg ; 24(3): 235-43, 1995.
Article in English | MEDLINE | ID: mdl-7653038

ABSTRACT

This study biomechanically evaluates solid and tubular interlocking nails in bovine neonatal femurs. Paired femurs from 40 neonatal dairy calves were obtained for mechanical testing. Intact femurs and four combinations of experimentally manipulated femurs (intact or ostectomized femurs with either a solid or tubular interlocking nail) were tested in craniocaudal and lateromedial bending, eccentric axial compression, and external torsion to evaluate composite rigidity, local/gap stiffness, and load to failure (compression and torsion only). In torsional composite rigidity, femurs with tubular interlocking nails were more complaint than intact femurs or intact femurs with solid interlocking nails (P < .001). Ostectomized femurs with solid interlocking nails were similar to intact femurs with tubular interlocking nails. Within femurs with tubular interlocking nails, ostectomized femurs were more compliant than intact femurs (P < .0001). In craniocaudal and lateromedial bending rigidity, ostectomized femurs were more complaint than intact femurs, regardless of interlocking nail type (P < .001). Within ostectomized femurs, tubular interlocking nails were more complaint than solid interlocking nails in craniocaudal bending (P < .05) and there was a similar trend in lateromedial bending (P = .06). In eccentric axial compression, local/gap stiffness was significantly greater in intact femurs compared with intact femurs with solid (48% of intact bone) or tubular (45% of intact bone) interlocking nails and ostectomized femurs with solid (18% of intact bone) or tubular (11% of intact bone) interlocking nails (P < .0001). In torsional testing, local/gap stiffness was not significantly different between intact femurs and intact femurs with interlocking nails, but was significantly lower in ostectomized femurs with solid (2% of intact bone) and tubular (0.2% of intact bone) interlocking nails (P < .0001).(ABSTRACT TRUNCATED AT 250 WORDS)


Subject(s)
Bone Nails/veterinary , Cattle/surgery , Femoral Fractures/veterinary , Femur/surgery , Fracture Fixation, Internal/veterinary , Animals , Animals, Newborn/injuries , Animals, Newborn/surgery , Biomechanical Phenomena , Bone Screws/veterinary , Cattle/injuries , Female , Femoral Fractures/surgery , Femur/physiology , Fracture Fixation, Internal/methods , In Vitro Techniques
14.
Vet Surg ; 25(5): 386-96, 1996.
Article in English | MEDLINE | ID: mdl-8879110

ABSTRACT

Using standard material testing techniques (bending stiffness, torsional stiffness, and maximum torque to failure or yield torque), the structural properties of interlocking nails (IN), canine femora, and IN/femur constructs were determined. Specimens that were tested included: 6 and 8 mm diameter IN with 5 to 10 screw holes (n = 18), and intact canine femora (n = 10), which also, with an IN inserted, formed the intact construct (IC) group, (n = 10). Specimens in the IC group were first tested with an 8 mm diameter IN with zero screws, followed by one and two screws (4.5 mm diameter) in the proximal and distal femur. A fracture model construct (FMC), (n = 14), consisting of a transverse femoral osteotomy with a 3 mm gap, was used with either 6 mm or 8 mm IN. In the 6 mm FMC, one and two 3.5 mm screws were used sequentially in the proximal and distal femoral segment. In the 8 mm FMC, one and two 3.5 mm screws and one and two 4.5 diameter screws were used similarly. When bending forces were applied parallel to IN screw holes, mean IN stiffness was 20% less than with forces perpendicular to the holes (n = 18), (P < .05). Eight-millimeter IN were 220% stiffer in torsion and 270% stiffer in bending than 6 mm IN (P < .05). Six-millimeter IN had approximately 32% of the bending stiffness and torsional stiffness of intact femurs (P < .05). Eight-millimeter IN had 93% and 79% of the bending stiffness and torsional stiffness, respectively, of intact femurs. Intact femur constructs (8 mm IN with four, 4.5 mm screws) had 147% of the bending stiffness (P < .05), and similar torsional stiffness and maximum torque, as intact femora (P > .05). The mean values of 6 mm FMC with four screws (3.5 mm) were 21% and 33% in torsional stiffness and bending stiffness, respectively, of intact femora values. When tested in torsion, 8 mm FMC failed by bone fracture; 6 mm FMC, in contrast, underwent plastic deformation. In comparing FMC stabilized with an 8 mm IN with two screws (4.5 mm diameter) in each bone segment, to intact femurs, the maximum torque was similar, FMC torsional stiffness was 40% (P < .05), and FMC bending stiffness was 65% (P < .05). These 8 mm FMC percentages are comparable to human IN fracture model construct values, indicating that the 8 mm IN/four screw construct should provide adequate stabilization for many canine diaphyseal femoral fractures.


Subject(s)
Dogs/surgery , Equipment Design/veterinary , Femoral Fractures/veterinary , Internal Fixators/veterinary , Surgery, Veterinary/methods , Animals , Equipment Design/standards , Femoral Fractures/surgery , Femur/surgery , Surgery, Veterinary/instrumentation
15.
Clin Orthop Relat Res ; (161): 146-53, 1981.
Article in English | MEDLINE | ID: mdl-6458436

ABSTRACT

Hypertrophic and oligotrophic nonunions were prepared by resection of a portion of the proximal ulna in dogs. In the hypertrophic nonunions, 20 muamps of direct current for eight weeks produced an increase in bone formation compared to the opposite control limb by radiography, photometry, point counting of new bone, and growth rate by sequential fluorochrome labeling and the dynamic uptake of 99mTc-labeled methylene disphosphonate. Oligotrophic nonunions were treated by plating and aspiration grafting in addition to direct-current stimulation. Ony the point counting of new bone showed a significant increase in bone formation with stimulation. Sequential fluorochrome labeling demonstrated that the new bone was laid down on existing bone and not primarily adjacent to the cathode within the fibrous nonunion. This finding supports the cell-mediated rather than physicochemical effect of electrostimulation.


Subject(s)
Electric Stimulation Therapy , Fractures, Ununited/therapy , Animals , Diphosphonates/metabolism , Dogs , Fractures, Ununited/metabolism , Fractures, Ununited/pathology , Microradiography , Osteogenesis , Photometry , Probability , Technetium/metabolism , Technetium Tc 99m Medronate , Time Factors , Ulna Fractures/therapy
16.
J Am Anim Hosp Assoc ; 35(1): 62-7, 1999.
Article in English | MEDLINE | ID: mdl-9934931

ABSTRACT

This case series describes four Scottish terriers with an osteopathic condition, characterized by multifocal absence of bone in the skull, cervical spine, and proximal radii, ulnae, and femora. All dogs were affected clinically; two dogs were euthanized due to progression of the disease, one died acutely, and one was euthanized for an oral melanoma. Histopathology in one case was characterized by osteoclastic osteolysis and replacement of bone with fibrous tissue. This disease has some characteristics of human osteolysis syndromes. Three of the dogs were related through pedigree analysis, and the pedigree of the other dog was not available. The name, idiopathic multifocal osteopathy, is used to describe a new disease in dogs, found particularly in Scottish terriers.


Subject(s)
Dog Diseases/diagnostic imaging , Osteolysis, Essential/veterinary , Animals , Breeding , Dogs , Female , Male , Osteolysis, Essential/diagnostic imaging , Prognosis , Radiography , Retrospective Studies , Syndrome
17.
Vet Surg ; 30(3): 261-8, 2001.
Article in English | MEDLINE | ID: mdl-11340558

ABSTRACT

OBJECTIVES: To determine thermal necrosis zone and the maximal temperature achieved with various electrocautery doses applied to the pubic symphysis of immature dogs, and to establish the minimal electrocautery dose needed to affect thermal necrosis of the germinal chondrocytes of the immature canine pubis. STUDY DESIGN: A randomized, controlled, prospective study. ANIMALS: Twelve puppies, 15 to 17 weeks of age. METHODS: Each treated puppy was randomly selected to receive 3 of 33 possible doses of electrical current applied at uniform intervals along the pelvic symphysis. Three treatment sites were sham-operated controls. All treatment zones were biopsied 7 days after application of electrocautery. Confocal laser microscopy with calcein green and ethidium homodimer red stains were used to determine cell type and viability within treatment and control zones. The physeal diameter and thermal necrosis zone were measured. Thermal necrosis zone and dose, and temperature and dose were compared using regression analysis. Prediction equation analysis was used to establish dose recommendations. RESULTS: Doses of 40 W produced a highly significant linear relationship (R(2) =.88, P <.01) with thermal necrosis zone, and a significant linear relationship (R(2) =.76, P <.02) with maximal temperature. CONCLUSIONS: The thermal necrosis zone within the pelvic symphysis and maximal temperature achieved can be reliably predicted using electrocautery doses of 40 W. For application of electrocautery to induce pubic symphysiodesis, doses should be chosen based on measured or estimated physeal size. Using prediction equation analysis, the surgeon can plan mean thermal necrosis zone with acceptable variance. CLINICAL RELEVANCE: Unipolar needle electrocautery can be used to reliably achieve symphyseal necrosis. Prediction equation analysis can be used to determine 40-W doses.


Subject(s)
Arthrodesis/veterinary , Dog Diseases/surgery , Electrocoagulation/veterinary , Pubic Symphysis/surgery , Animals , Arthrodesis/methods , Arthrodesis/standards , Dogs , Electrocoagulation/methods , Microscopy, Confocal , Necrosis , Prospective Studies , Pubic Symphysis/pathology , Staining and Labeling , Temperature
18.
J Am Anim Hosp Assoc ; 33(3): 275-81, 1997.
Article in English | MEDLINE | ID: mdl-9138240

ABSTRACT

A new method of dynamic ultrasonographic evaluation of passive coxofemoral joint laxity was used to examine a total of 30 greyhound (n = 13) and nongreyhound (n = 17) puppies. Puppies were evaluated sonographically at four, six, eight, 12, 16, and 26 weeks of age. The coxofemoral joints were distracted manually, and the femoral head displacements were measured during distraction. The greyhounds had significantly smaller (p less than 0.01) maximum distraction distance (mean +/- standard deviation [SD], 0.11 +/- 0.04 cm) than nongreyhound puppies (mean +/- SD, 0.26 +/- 0.10 cm). In six- to eight-week-old puppies, the maximum distraction distance was correlated significantly (p of 0.0001, adjusted correlation coefficient [r2] of 0.27) with stress radiographic indices. Coxofemoral joints interpreted as being abnormal on hip-extended radiographs taken at one year of age were associated significantly (p of 0.0001) with higher maximum distraction distances in six- to eight-week-old puppies.


Subject(s)
Dog Diseases/diagnostic imaging , Hip Joint/diagnostic imaging , Joint Instability/veterinary , Analysis of Variance , Animals , Dog Diseases/physiopathology , Dogs , Hip Dysplasia, Canine/diagnosis , Hip Dysplasia, Canine/etiology , Hip Dysplasia, Canine/physiopathology , Hip Joint/pathology , Image Processing, Computer-Assisted/methods , Joint Instability/diagnostic imaging , Predictive Value of Tests , Radiography , Ultrasonography
19.
J Am Anim Hosp Assoc ; 34(4): 339-47, 1998.
Article in English | MEDLINE | ID: mdl-9657168

ABSTRACT

Hip joint laxity was evaluated in four breeds (i.e., greyhound, Labrador retriever, Irish setter, hound mixed-breed) of puppies (n=32) by Ortolani's and Bardens' maneuvers, by subjective assessment of radiographs (Orthopedic Foundation for Animals [OFA] method), and by four radiographic measurement indices. Puppies were studied at four, six-to-10, 16-to-18, and 52 weeks of age. The purpose of this study was to compare palpation and radiographic methods of hip laxity detection in puppies for predicting the development of degenerative joint disease (DJD) by one year of age. Twenty-seven (42%) hips developed DJD. Ortolani's method was not a reliable predictor of hip dysplasia at six-to-10 weeks; it was significantly predictive at 16-to-18 weeks but had a high incidence of false negatives. Bardens' and subjective (OFA) assessment methods were not reliable at six-to-10 or 16-to-18 weeks. Radiographic measurements taken with femurs in a neutral position and hips distracted (distraction index [DI] and Norberg angle) and measurements taken with femurs extended in OFA position (Norberg angle) of six- to 10-week-old puppies accurately predicted DJD occurrence by one year of age (p less than 0.01). Distraction index measurement (PennHIP method) was the most accurate in predicting the development of DJD (p less than 0.001). Distraction index radiography in puppies six-to-10 and 16-to-18 weeks of age was the most reliable predictor of hip dysplasia. Norberg angle measurement was more reliable during hip distraction than when hips were measured in the OFA position in 16- to 18-week-old puppies, but had similar reliability in six- to 10-week-old puppies.


Subject(s)
Hip Dysplasia, Canine/diagnosis , Hip Joint/diagnostic imaging , Palpation/veterinary , Age Factors , Animals , Breeding , Dogs , Hip Dysplasia, Canine/diagnostic imaging , Joint Instability/diagnosis , Joint Instability/diagnostic imaging , Joint Instability/veterinary , Predictive Value of Tests , Radiography
20.
Vet Surg ; 30(3): 201-17, 2001.
Article in English | MEDLINE | ID: mdl-11340551

ABSTRACT

OBJECTIVE: To determine the long-term effects of juvenile pubic symphysiodesis (JPS) in dysplastic puppies. STUDY DESIGN: Prospective, randomized, clinical trial. ANIMALS: Seven dysplastic Chesapeake Bay retrievers and 2 beagle-crosses (BX1 and 2). METHODS: Five puppies had JPS performed with electrocauterization at 12, 16, 20, 22, and 24 weeks of age, respectively. Two puppies served as controls. BX1 and BX2 were used to obtain biopsies of the symphysis. Hips were evaluated for: pelvic development (transverse computerized tomography for acetabular angle [AA] and dorsal acetabular rim angle [DARA]); laxity [hip extended and stress radiography [distraction index (DI)]); Ortolani maneuver with reduction angles; acetabular coverage (Norberg angles); and function (coxofemoral range of motion, hip pain, and gait analysis by force-plate technique at 44 and 137 weeks of age). RESULTS: The pubis fused prematurely in every puppy that was operated on with the JPS technique. Greater acetabular responses were related to younger ages at surgery. The final mean AA in dogs that had JPS was 25 degrees greater than preoperative values; 40% increased over control. The DARA final mean was 10 degrees, 52% less than preoperative values and 46% less than control. The final mean DI in dogs having JPS was 0.28, 47% improved over preoperative values and 58% better than control. Mean pelvic dimensions in dogs that had JPS were 18% less than control. Gait analyses were normal for all dogs at 137 weeks. No urinary or bowel complications occurred. CONCLUSIONS: Significant ventrolateral acetabular rotation, increased hip coverage, diminished hip laxity, normal pain-free gait, and insignificantly reduced pelvic size occurred after JPS. CLINICAL SIGNIFICANCE: Dysplastic hips in young dogs were significantly improved by JPS.


Subject(s)
Arthrodesis/veterinary , Dogs/surgery , Hip Dysplasia, Canine/surgery , Pubic Symphysis/surgery , Age Factors , Animals , Female , Hip Dysplasia, Canine/complications , Hip Dysplasia, Canine/diagnostic imaging , Male , Pain/veterinary , Pelvic Bones/physiopathology , Pelvic Bones/surgery , Prospective Studies , Range of Motion, Articular , Tomography, X-Ray Computed/veterinary
SELECTION OF CITATIONS
SEARCH DETAIL