[The urgency of the application of the medical sanitary passport in the system for chemical safety in the areas of location of high-risk chemical facilities in the Russian Federation].

The main provisions concerning the need for a creation of medical and sanitary passport for territories in the protective measures zones (PMZ) of storage facilities and facilities for the destruction of chemical weapons (FDCW) are presented in the article. The assessment of results of certification of the territory of PMZ and FDCW in "Maradykovsky" in the Kirov region has been done.

[The manifestations of toxicity of nanoparticles (a review)].

The analysis of the data available in the literature has shown that nanoparticles (NP) have a high toxicity than usual microparticles, can penetrate unchanged across the cell barriers, the blood-brain barrier into the central nervous system, circulate and accumulate in the organs and tissues, by inducing more significant pathomorphological lesions in the visceral organs, and have a long elimination half-life. The toxicity of HPs is determined by their shape and sizes; moreover, minute fusiform particles cause more destructive effects than similar spherical particles; upon exposure, there is a clear dose-effect relationship. According to exposure to NPs, the classical target organs for the latter are the lung, liver, kidney, brain, gastrointestinal tract.