Search | Virtual Health Library

1.

APOE4 impairs the microglial response in Alzheimer's disease by inducing TGFß-mediated checkpoints.

Yin, Zhuoran; Rosenzweig, Neta; Kleemann, Kilian L; Zhang, Xiaoming; Brandão, Wesley; Margeta, Milica A; Schroeder, Caitlin; Sivanathan, Kisha N; Silveira, Sebastian; Gauthier, Christian; Mallah, Dania; Pitts, Kristen M; Durao, Ana; Herron, Shawn; Shorey, Hannah; Cheng, Yiran; Barry, Jen-Li; Krishnan, Rajesh K; Wakelin, Sam; Rhee, Jared; Yung, Anthony; Aronchik, Michael; Wang, Chao; Jain, Nimansha; Bao, Xin; Gerrits, Emma; Brouwer, Nieske; Deik, Amy; Tenen, Daniel G; Ikezu, Tsuneya; Santander, Nicolas G; McKinsey, Gabriel L; Baufeld, Caroline; Sheppard, Dean; Krasemann, Susanne; Nowarski, Roni; Eggen, Bart J L; Clish, Clary; Tanzi, Rudolph E; Madore, Charlotte; Arnold, Thomas D; Holtzman, David M; Butovsky, Oleg.

Nat Immunol ; 24(11): 1839-1853, 2023 Nov.

Article in English | MEDLINE | ID: mdl-37749326

2.

Cold Mechanical Isolation of Placental Macrophages as a Method to Limit Procedure-Induced Activation of Macrophages.

Eskandar, Sharon; Bezemer, Romy E; Eggen, Bart J L; Prins, Jelmer R.

J Immunol ; 211(12): 1868-1876, 2023 12 15.

Article in English | MEDLINE | ID: mdl-37909834

3.

Early amyloid-induced changes in microglia gene expression in male APP/PS1 mice.

Oshima, Takuya; Kater, Mandy S J; Huffels, Christiaan F M; Wesseling, Evelyn M; Middeldorp, Jinte; Hol, Elly M; Verheijen, Mark H G; Smit, August B; Boddeke, Erik W G M; Eggen, Bart J L.

J Neurosci Res ; 102(3): e25295, 2024 Mar.

Article in English | MEDLINE | ID: mdl-38515329

4.

How the cGAS-STING system links inflammation and cognitive decline.

Eggen, Bart J L.

Nature ; 620(7973): 280-282, 2023 Aug.

Article in English | MEDLINE | ID: mdl-37532848

5.

Microglia morphotyping in the adult mouse CNS using hierarchical clustering on principal components reveals regional heterogeneity but no sexual dimorphism.

van Weering, Hilmar R J; Nijboer, Tjalling W; Brummer, Maaike L; Boddeke, Erik W G M; Eggen, Bart J L.

Glia ; 71(10): 2356-2371, 2023 10.

Article in English | MEDLINE | ID: mdl-37293807

6.

Characterizing microglial gene expression in a model of secondary progressive multiple sclerosis.

Vainchtein, Ilia D; Alsema, Astrid M; Dubbelaar, Marissa L; Grit, Corien; Vinet, Jonathan; van Weering, Hilmar R J; Al-Izki, Sarah; Biagini, Giuseppe; Brouwer, Nieske; Amor, Sandra; Baker, David; Eggen, Bart J L; Boddeke, Erik W G M; Kooistra, Susanne M.

Glia ; 71(3): 588-601, 2023 Mar.

Article in English | MEDLINE | ID: mdl-36377669

7.

Prevention of microgliosis halts early memory loss in a mouse model of Alzheimer's disease.

Kater, Mandy S J; Huffels, Christiaan F M; Oshima, Takuya; Renckens, Niek S; Middeldorp, Jinte; Boddeke, Erik W G M; Smit, August B; Eggen, Bart J L; Hol, Elly M; Verheijen, Mark H G.

Brain Behav Immun ; 107: 225-241, 2023 Jan.

Article in English | MEDLINE | ID: mdl-36270437

8.

Single-nucleus RNA sequencing of midbrain blood-brain barrier cells in schizophrenia reveals subtle transcriptional changes with overall preservation of cellular proportions and phenotypes.

Puvogel, Sofía; Alsema, Astrid; Kracht, Laura; Webster, Maree J; Weickert, Cynthia Shannon; Sommer, Iris E C; Eggen, Bart J L.

Mol Psychiatry ; 27(11): 4731-4740, 2022 Nov.

Article in English | MEDLINE | ID: mdl-36192459

9.

An emerging role for microglia in stress-effects on memory.

Sanguino-Gómez, Jeniffer; Buurstede, Jacobus C; Abiega, Oihane; Fitzsimons, Carlos P; Lucassen, Paul J; Eggen, Bart J L; Lesuis, Sylvie L; Meijer, Onno C; Krugers, Harm J.

Eur J Neurosci ; 55(9-10): 2491-2518, 2022 05.

Article in English | MEDLINE | ID: mdl-33724565

10.

Epigenetic regulation of innate immune memory in microglia.

Zhang, Xiaoming; Kracht, Laura; Lerario, Antonio M; Dubbelaar, Marissa L; Brouwer, Nieske; Wesseling, Evelyn M; Boddeke, Erik W G M; Eggen, Bart J L; Kooistra, Susanne M.

J Neuroinflammation ; 19(1): 111, 2022 May 14.

Article in English | MEDLINE | ID: mdl-35568856

11.

Exploring reported genes of microglia RNA-sequencing data: Uses and considerations.

van Wageningen, Thecla A; Gerrits, Emma; Palacin I Bonson, Sara; Huitinga, Inge; Eggen, Bart J L; van Dam, Anne-Marie.

Glia ; 69(12): 2933-2946, 2021 12.

Article in English | MEDLINE | ID: mdl-34409652

12.

The effects of postmortem delay on mouse and human microglia gene expression.

Heng, Yang; Dubbelaar, Marissa L; Marie, Suely K N; Boddeke, Erik W G M; Eggen, Bart J L.

Glia ; 69(4): 1053-1060, 2021 04.

Article in English | MEDLINE | ID: mdl-33296111

13.

Type I interferon-activated microglia are critical for neuromyelitis optica pathology.

Wlodarczyk, Agnieszka; Khorooshi, Reza; Marczynska, Joanna; Holtman, Inge R; Burton, Mark; Jensen, Kirstine Nolling; Blaabjerg, Morten; Meyer, Morten; Thomassen, Mads; Eggen, Bart J L; Asgari, Nasrin; Owens, Trevor.

Glia ; 69(4): 943-953, 2021 04.

Article in English | MEDLINE | ID: mdl-33241604

14.

Regionally diverse astrocyte subtypes and their heterogeneous response to EAE.

Borggrewe, Malte; Grit, Corien; Vainchtein, Ilia D; Brouwer, Nieske; Wesseling, Evelyn M; Laman, Jon D; Eggen, Bart J L; Kooistra, Susanne M; Boddeke, Erik W G M.

Glia ; 69(5): 1140-1154, 2021 05.

Article in English | MEDLINE | ID: mdl-33332631

15.

Intrinsic DNA damage repair deficiency results in progressive microglia loss and replacement.

Zhang, Xiaoming; Heng, Yang; Kooistra, Susanne M; van Weering, Hilmar R J; Brummer, Maaike L; Gerrits, Emma; Wesseling, Evelyn M; Brouwer, Nieske; Nijboer, Tjalling W; Dubbelaar, Marissa L; Boddeke, Erik W G M; Eggen, Bart J L.

Glia ; 69(3): 729-745, 2021 03.

Article in English | MEDLINE | ID: mdl-33068332

16.

Systemic administration of ß-glucan induces immune training in microglia.

Heng, Yang; Zhang, Xiaoming; Borggrewe, Malte; van Weering, Hilmar R J; Brummer, Maaike L; Nijboer, Tjalling W; Joosten, Leo A B; Netea, Mihai G; Boddeke, Erik W G M; Laman, Jon D; Eggen, Bart J L.

J Neuroinflammation ; 18(1): 57, 2021 Feb 22.

Article in English | MEDLINE | ID: mdl-33618716

17.

Distinct amyloid-ß and tau-associated microglia profiles in Alzheimer's disease.

Gerrits, Emma; Brouwer, Nieske; Kooistra, Susanne M; Woodbury, Maya E; Vermeiren, Yannick; Lambourne, Mirjam; Mulder, Jan; Kummer, Markus; Möller, Thomas; Biber, Knut; Dunnen, Wilfred F A den; De Deyn, Peter P; Eggen, Bart J L; Boddeke, Erik W G M.

Acta Neuropathol ; 141(5): 681-696, 2021 05.

Article in English | MEDLINE | ID: mdl-33609158

18.

Somatic TARDBP variants as a cause of semantic dementia.

van Rooij, Jeroen; Mol, Merel O; Melhem, Shamiram; van der Wal, Pelle; Arp, Pascal; Paron, Francesca; Donker Kaat, Laura; Seelaar, Harro; Miedema, Suzanne S M; Oshima, Takuya; Eggen, Bart J L; Uitterlinden, André; van Meurs, Joyce; van Kesteren, Ronald E; Smit, August B; Buratti, Emanuele; van Swieten, John C.

Brain ; 143(12): 3827-3841, 2020 12 01.

Article in English | MEDLINE | ID: mdl-33155043

19.

Transcriptional profiling of microglia; current state of the art and future perspectives.

Gerrits, Emma; Heng, Yang; Boddeke, Erik W G M; Eggen, Bart J L.

Glia ; 68(4): 740-755, 2020 04.

Article in English | MEDLINE | ID: mdl-31846124

20.

Transcriptional heterogeneity between primary adult grey and white matter astrocytes underlie differences in modulation of in vitro myelination.

Werkman, Inge L; Dubbelaar, Marissa L; van der Vlies, Pieter; de Boer-Bergsma, Jelkje J; Eggen, Bart J L; Baron, Wia.

J Neuroinflammation ; 17(1): 373, 2020 Dec 11.

Article in English | MEDLINE | ID: mdl-33308248

Virtual Health Library

United States - Mexico Border

Your selection (0)

Export format:

Export: