Search | Virtual Health Library

1.

Timing of the loss of Pten protein determines disease severity in a mouse model of myeloid malignancy.

Liu, Y Lucy; Yan, Yan; Webster, Cody; Shao, Lijian; Lensing, Shelly Y; Ni, Hongyu; Feng, Wei; Colorado, Natalia; Pathak, Rupak; Xiang, Zhifu; Hauer-Jensen, Martin; Li, Shaoguang; Zhou, Daohong; Emanuel, Peter D.

Blood ; 127(15): 1912-22, 2016 Apr 14.

Article in English | MEDLINE | ID: mdl-26764354

2.

Subclonal mutations in SETBP1 confer a poor prognosis in juvenile myelomonocytic leukemia.

Stieglitz, Elliot; Troup, Camille B; Gelston, Laura C; Haliburton, John; Chow, Eric D; Yu, Kristie B; Akutagawa, Jon; Taylor-Weiner, Amaro N; Liu, Y Lucy; Wang, Yong-Dong; Beckman, Kyle; Emanuel, Peter D; Braun, Benjamin S; Abate, Adam; Gerbing, Robert B; Alonzo, Todd A; Loh, Mignon L.

Blood ; 125(3): 516-24, 2015 Jan 15.

Article in English | MEDLINE | ID: mdl-25395418

3.

Hallway gossip between Ras and PI3K pathways.

Emanuel, Peter D.

Blood ; 123(18): 2751-3, 2014 May 01.

Article in English | MEDLINE | ID: mdl-24786454

4.

Phase II/III trial of a pre-transplant farnesyl transferase inhibitor in juvenile myelomonocytic leukemia: a report from the Children's Oncology Group.

Stieglitz, Elliot; Ward, Ashley F; Gerbing, Robert B; Alonzo, Todd A; Arceci, Robert J; Liu, Y Lucy; Emanuel, Peter D; Widemann, Brigitte C; Cheng, Jennifer W; Jayaprakash, Nalini; Balis, Frank M; Castleberry, Robert P; Bunin, Nancy J; Loh, Mignon L; Cooper, Todd M.

Pediatr Blood Cancer ; 62(4): 629-36, 2015 Apr.

Article in English | MEDLINE | ID: mdl-25704135

5.

Imatinib 800 mg daily induces deeper molecular responses than imatinib 400 mg daily: results of SWOG S0325, an intergroup randomized PHASE II trial in newly diagnosed chronic phase chronic myeloid leukaemia.

Deininger, Michael W; Kopecky, Kenneth J; Radich, Jerald P; Kamel-Reid, Suzanne; Stock, Wendy; Paietta, Elisabeth; Emanuel, Peter D; Tallman, Martin; Wadleigh, Martha; Larson, Richard A; Lipton, Jeffrey H; Slovak, Marilyn L; Appelbaum, Frederick R; Druker, Brian J.

Br J Haematol ; 164(2): 223-32, 2014 Jan.

Article in English | MEDLINE | ID: mdl-24383843

6.

Mutations in GATA2 are rare in juvenile myelomonocytic leukemia.

Stieglitz, Elliot; Liu, Y Lucy; Emanuel, Peter D; Castleberry, Robert P; Cooper, Todd M; Shannon, Kevin M; Loh, Mignon L.

Blood ; 123(9): 1426-7, 2014 Feb 27.

Article in English | MEDLINE | ID: mdl-24578498

7.

Mutations in CBL occur frequently in juvenile myelomonocytic leukemia.

Loh, Mignon L; Sakai, Debbie S; Flotho, Christian; Kang, Michelle; Fliegauf, Manfred; Archambeault, Sophie; Mullighan, Charles G; Chen, Leslie; Bergstraesser, Eva; Bueso-Ramos, Carlos E; Emanuel, Peter D; Hasle, Henrik; Issa, Jean-Pierre; van den Heuvel-Eibrink, Marry M; Locatelli, Franco; Stary, Jan; Trebo, Monica; Wlodarski, Marcin; Zecca, Marco; Shannon, Kevin M; Niemeyer, Charlotte M.

Blood ; 114(9): 1859-63, 2009 Aug 27.

Article in English | MEDLINE | ID: mdl-19571318

8.

PTEN transcript variants caused by illegitimate splicing in "aged" blood samples and EBV-transformed cell lines.

Liu, Yunying; Malaviarachchi, Priyangi; Beggs, Marjorie; Emanuel, Peter D.

Hum Genet ; 128(6): 609-14, 2010 Dec.

Article in English | MEDLINE | ID: mdl-20839010

9.

Sustained fetal hematopoiesis causes juvenile death from leukemia: evidence from a dual-age-specific mouse model.

Vara, Nitza; Liu, Yuqing; Yan, Yan; Lensing, Shelly Y; Colorado, Natalia; Robinson, Delli; Zhang, Jingliao; Zhang, Xin; Peterson, Erich A; Baltz, Nicholas J; Zhou, Daohong; Bertaina, Alice; Johann, Donald J; Emanuel, Peter D; Liu, Y Lucy.

Blood Adv ; 4(15): 3728-3740, 2020 08 11.

Article in English | MEDLINE | ID: mdl-32777070

10.

Alterations in RNA-binding activities of IRES-regulatory proteins as a mechanism for physiological variability and pathological dysregulation of IGF-IR translational control in human breast tumor cells.

Meng, Zheng; Jackson, Nateka L; Choi, Hyoungsoo; King, Peter H; Emanuel, Peter D; Blume, Scott W.

J Cell Physiol ; 217(1): 172-83, 2008 Oct.

Article in English | MEDLINE | ID: mdl-18452152

11.

mrtl-A translation/localization regulatory protein encoded within the human c-myc locus and distributed throughout the endoplasmic and nucleoplasmic reticular network.

Choi, Hyoungsoo; Jackson, Nateka L; Shaw, Denise R; Emanuel, Peter D; Liu, Y Lucy; Tousson, Albert; Meng, Zheng; Blume, Scott W.

J Cell Biochem ; 105(4): 1092-108, 2008 Nov 01.

Article in English | MEDLINE | ID: mdl-18816594

12.

A case of proteasome-associated auto-inflammatory syndrome with compound heterozygous mutations.

McDermott, Amelia; Jesus, Adriana Almeida; Liu, Yin; Kim, Peter; Jacks, Jennifer; Montealegre Sanchez, Gina A; Chen, Yongqing; Kannan, Aarthi; Schnebelen, Alicia; Emanuel, Peter D; Shalin, Sara; Hiatt, Kim; Goldbach-Mansky, Raphaela; Gao, Ling.

J Am Acad Dermatol ; 69(1): e29-32, 2013 Jul.

Article in English | MEDLINE | ID: mdl-23768303

13.

RAS pathway mutations in juvenile myelomonocytic leukemia.

Emanuel, Peter D.

Acta Haematol ; 119(4): 207-11, 2008.

Article in English | MEDLINE | ID: mdl-18566538

14.

PTEN is indispensable for cells to respond to MAPK inhibitors in myeloid leukemia.

Zhang, Jingliao; Xiang, Zhifu; Malaviarachchi, Priyangi A; Yan, Yan; Baltz, Nicholas J; Emanuel, Peter D; Liu, Y Lucy.

Cell Signal ; 50: 72-79, 2018 Oct.

Article in English | MEDLINE | ID: mdl-29964149

15.

M1 and M2 macrophages differentially regulate hematopoietic stem cell self-renewal and ex vivo expansion.

Luo, Yi; Shao, Lijian; Chang, Jianhui; Feng, Wei; Liu, Y Lucy; Cottler-Fox, Michele H; Emanuel, Peter D; Hauer-Jensen, Martin; Bernstein, Irwin D; Liu, Lingbo; Chen, Xing; Zhou, Jianfeng; Murray, Peter J; Zhou, Daohong.

Blood Adv ; 2(8): 859-870, 2018 04 24.

Article in English | MEDLINE | ID: mdl-29666049

16.

The ELAV RNA-stability factor HuR binds the 5'-untranslated region of the human IGF-IR transcript and differentially represses cap-dependent and IRES-mediated translation.

Meng, Zheng; King, Peter H; Nabors, L Burt; Jackson, Nateka L; Chen, Ching-Yi; Emanuel, Peter D; Blume, Scott W.

Nucleic Acids Res ; 33(9): 2962-79, 2005.

Article in English | MEDLINE | ID: mdl-15914670

17.

Managing Expectations in the Transition to Proof of Concept Studies.

Kieber-Emmons, Thomas; Makhoul, Issam; Pennisi, Angela; Siegel, Eric R; Emanuel, Peter D; Monzavi-Karbassi, Bejotaloh; Steplewski, Zenon; Beck, J Thaddeus; Hutchins, Laura F.

Rev Recent Clin Trials ; 12(2): 111-123, 2017.

Article in English | MEDLINE | ID: mdl-28325150

18.

Targeting tumor-associated carbohydrate antigens: a phase I study of a carbohydrate mimetic-peptide vaccine in stage IV breast cancer subjects.

Hutchins, Laura F; Makhoul, Issam; Emanuel, Peter D; Pennisi, Angela; Siegel, Eric R; Jousheghany, Fariba; Guo, Xueyan; Pashov, Anastas D; Monzavi-Karbassi, Behjatolah; Kieber-Emmons, Thomas.

Oncotarget ; 8(58): 99161-99178, 2017 Nov 17.

Article in English | MEDLINE | ID: mdl-29228761

19.

Proteasome-associated autoinflammatory syndromes: advances in pathogeneses, clinical presentations, diagnosis, and management.

McDermott, Amelia; Jacks, Jennifer; Kessler, Marcus; Emanuel, Peter D; Gao, Ling.

Int J Dermatol ; 54(2): 121-9, 2015 Feb.

Article in English | MEDLINE | ID: mdl-25521013

20.

MYC amplification in multiple marker chromosomes and EZH2 microdeletion in a man with acute myeloid leukemia.

Xiang, Zhifu; Abdallah, Al-Ola; Govindarajan, Rangaswamy; Mehta, Paulette; Emanuel, Peter D; Papenhausen, Peter; Schichman, Steven A.

Cancer Genet ; 208(3): 96-100, 2015 Mar.

Article in English | MEDLINE | ID: mdl-25800664

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