Search | Virtual Health Library

1.

Efficacy and Safety of a Recombinant Plant-Based Adjuvanted Covid-19 Vaccine.

Hager, Karen J; Pérez Marc, Gonzalo; Gobeil, Philipe; Diaz, Ricardo S; Heizer, Gretchen; Llapur, Conrado; Makarkov, Alexander I; Vasconcellos, Eduardo; Pillet, Stéphane; Riera, Fernando; Saxena, Pooja; Geller Wolff, Priscila; Bhutada, Kapil; Wallace, Garry; Aazami, Hessam; Jones, Christine E; Polack, Fernando P; Ferrara, Luciana; Atkins, Judith; Boulay, Iohann; Dhaliwall, Jiwanjeet; Charland, Nathalie; Couture, Manon M J; Jiang-Wright, Julia; Landry, Nathalie; Lapointe, Sophie; Lorin, Aurélien; Mahmood, Asif; Moulton, Lawrence H; Pahmer, Emmy; Parent, Julie; Séguin, Annie; Tran, Luan; Breuer, Thomas; Ceregido, Maria-Angeles; Koutsoukos, Marguerite; Roman, François; Namba, Junya; D'Aoust, Marc-André; Trepanier, Sonia; Kimura, Yosuke; Ward, Brian J.

N Engl J Med ; 386(22): 2084-2096, 2022 06 02.

Article in English | MEDLINE | ID: mdl-35507508

2.

A small-molecule inhibitor of C5 complement protein.

Jendza, Keith; Kato, Mitsunori; Salcius, Michael; Srinivas, Honnappa; De Erkenez, Andrea; Nguyen, Anh; McLaughlin, Doug; Be, Celine; Wiesmann, Christian; Murphy, Jason; Bolduc, Philippe; Mogi, Muneto; Duca, Jose; Namil, Abdel; Capparelli, Michael; Darsigny, Veronique; Meredith, Erik; Tichkule, Ritesh; Ferrara, Luciana; Heyder, Jessica; Liu, Fang; Horton, Patricia A; Romanowski, Michael J; Schirle, Markus; Mainolfi, Nello; Anderson, Karen; Michaud, Gregory A.

Nat Chem Biol ; 15(7): 666-668, 2019 07.

Article in English | MEDLINE | ID: mdl-31209353

3.

Citron-N is a neuronal Rho-associated protein involved in Golgi organization through actin cytoskeleton regulation.

Camera, Paola; da Silva, Jorge Santos; Griffiths, Gareth; Giuffrida, Maria Gabriella; Ferrara, Luciana; Schubert, Vanessa; Imarisio, Sara; Silengo, Lorenzo; Dotti, Carlos G; Di Cunto, Ferdinando.

Nat Cell Biol ; 5(12): 1071-8, 2003 Dec.

Article in English | MEDLINE | ID: mdl-14595335

4.

Discovery of 4-((2S,4S)-4-Ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable to Treating a Diverse Array of Complement Mediated Diseases.

Mainolfi, Nello; Ehara, Takeru; Karki, Rajeshri G; Anderson, Karen; Mac Sweeney, Aengus; Liao, Sha-Mei; Argikar, Upendra A; Jendza, Keith; Zhang, Chun; Powers, James; Klosowski, Daniel W; Crowley, Maura; Kawanami, Toshio; Ding, Jian; April, Myriam; Forster, Cornelia; Serrano-Wu, Michael; Capparelli, Michael; Ramqaj, Rrezarta; Solovay, Catherine; Cumin, Frederic; Smith, Thomas M; Ferrara, Luciana; Lee, Wendy; Long, Debby; Prentiss, Melissa; De Erkenez, Andrea; Yang, Louis; Liu, Fang; Sellner, Holger; Sirockin, Finton; Valeur, Eric; Erbel, Paulus; Ostermeier, Daniela; Ramage, Paul; Gerhartz, Bernd; Schubart, Anna; Flohr, Stefanie; Gradoux, Nathalie; Feifel, Roland; Vogg, Barbara; Wiesmann, Christian; Maibaum, Jürgen; Eder, Jörg; Sedrani, Richard; Harrison, Richard A; Mogi, Muneto; Jaffee, Bruce D; Adams, Christopher M.

J Med Chem ; 63(11): 5697-5722, 2020 06 11.

Article in English | MEDLINE | ID: mdl-32073845

5.

Recovery of cell cycle delay following targeted gene repair by oligonucleotides.

Ferrara, Luciana; Engstrom, Julia U; Schwartz, Timothy; Parekh-Olmedo, Hetal; Kmiec, Eric B.

DNA Repair (Amst) ; 6(10): 1529-35, 2007 Oct 01.

Article in English | MEDLINE | ID: mdl-17560837

6.

A Novel Selective Soluble Guanylate Cyclase Activator, MGV354, Lowers Intraocular Pressure in Preclinical Models, Following Topical Ocular Dosing.

Prasanna, Ganesh; Ferrara, Luciana; Adams, Christopher; Ehara, Takeru; Li, Byron; Yang, Louis; Xiang, Chuanxi; Ng, Christopher Thow Hing; Kim, Sean; Towler, Christopher; Topley, Todd; McAllister, Cale; Ghosh, Malay; Newton, Ronald; Stacy, Rebecca; Rice, Dennis S; Mogi, Muneto.

Invest Ophthalmol Vis Sci ; 59(5): 1704-1716, 2018 04 01.

Article in English | MEDLINE | ID: mdl-29610853

7.

The Discovery of ( S)-1-(6-(3-((4-(1-(Cyclopropanecarbonyl)piperidin-4-yl)-2-methylphenyl)amino)-2,3-dihydro-1 H-inden-4-yl)pyridin-2-yl)-5-methyl-1 H-pyrazole-4-carboxylic Acid, a Soluble Guanylate Cyclase Activator Specifically Designed for Topical Ocular Delivery as a Therapy for Glaucoma.

Ehara, Takeru; Adams, Christopher M; Bevan, Doug; Ji, Nan; Meredith, Erik L; Belanger, David B; Powers, James; Kato, Mitsunori; Solovay, Catherine; Liu, Donglei; Capparelli, Michael; Bolduc, Philippe; Grob, Jonathan E; Daniels, Matthew H; Ferrara, Luciana; Yang, Louis; Li, Byron; Towler, Christopher S; Stacy, Rebecca C; Prasanna, Ganesh; Mogi, Muneto.

J Med Chem ; 61(6): 2552-2570, 2018 03 22.

Article in English | MEDLINE | ID: mdl-29498522

8.

Targeted gene repair activates Chk1 and Chk2 and stalls replication in corrected cells.

Ferrara, Luciana; Kmiec, Eric B.

DNA Repair (Amst) ; 5(4): 422-31, 2006 Apr 08.

Article in English | MEDLINE | ID: mdl-16414312

9.

Camptothecin enhances the frequency of oligonucleotide-directed gene repair in mammalian cells by inducing DNA damage and activating homologous recombination.

Ferrara, Luciana; Kmiec, Eric B.

Nucleic Acids Res ; 32(17): 5239-48, 2004.

Article in English | MEDLINE | ID: mdl-15466591

10.

Role of citron kinase in dendritic morphogenesis of cortical neurons.

Di Cunto, Ferdinando; Ferrara, Luciana; Curtetti, Roberta; Imarisio, Sara; Guazzone, Simona; Broccoli, Vania; Bulfone, Alessandro; Altruda, Fiorella; Vercelli, Alessandro; Silengo, Lorenzo.

Brain Res Bull ; 60(4): 319-27, 2003 May 30.

Article in English | MEDLINE | ID: mdl-12781320

11.

Enhanced oligonucleotide-directed gene targeting in mammalian cells following treatment with DNA damaging agents.

Ferrara, Luciana; Parekh-Olmedo, Hetal; Kmiec, Eric B.

Exp Cell Res ; 300(1): 170-9, 2004 Oct 15.

Article in English | MEDLINE | ID: mdl-15383324

12.

Mananciais: diagnóstico e políticas habitacionais / Watershed: diagnosis and housing policies

Santoro, Paula Freire; Ferrara, Luciana Nicolau; Whately, Marussia.

São Paulo/SP; Instituto Socioambiental; 2009. 127 p. ilus, tab, mapas, graf.

Monography in Portuguese | LILACS, COVISA-Acervo | ID: lil-626013

13.

Mananciais: uma nova realidade? / Springs: a new reality?

Whately, Marussia; Santoro, Paula Freire; Ferrara, Luciana Nicolau; Bajesteiro, Fernanda Blauth.

São Paulo/SP; Instituto Socioambiental; out. 2008. 335 p. ilus, mapas, graf, tab.

Monography in Portuguese | LILACS, COVISA-Acervo | ID: lil-626016

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