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1.
Predicted deleterious variants in ABCA1, LPL, LPA and KIF6 are associated with statin response and adverse events in patients with familial hypercholesterolemia and disturb protein structure and stability.
Pharmacogenet Genomics
; 34(4): 91-104, 2024 Jun 01.
Article
in English
| MEDLINE | ID: mdl-38682317
2.
Innovative Microemulsion Loaded with Unusual Dimeric Flavonoids from Fridericia platyphylla (Cham.) L.G. Lohmann Roots.
AAPS PharmSciTech
; 24(8): 212, 2023 Oct 17.
Article
in English
| MEDLINE | ID: mdl-37848719
3.
Rational Design, Synthesis, and Mechanism of (3S,4R)-3-Amino-4-(difluoromethyl)cyclopent-1-ene-1-carboxylic Acid: Employing a Second-Deprotonation Strategy for Selectivity of Human Ornithine Aminotransferase over GABA Aminotransferase.
J Am Chem Soc
; 144(12): 5629-5642, 2022 03 30.
Article
in English
| MEDLINE | ID: mdl-35293728
4.
Do Go Chasing Waterfalls: Enoyl Reductase (FabI) in Complex with Inhibitors Stabilizes the Tetrameric Structure and Opens Water Channels.
J Chem Inf Model
; 62(22): 5746-5761, 2022 11 28.
Article
in English
| MEDLINE | ID: mdl-36343333
5.
Design, synthesis and biological activity of novel substituted 3-benzoic acid derivatives as MtDHFR inhibitors.
Bioorg Med Chem
; 28(15): 115600, 2020 08 01.
Article
in English
| MEDLINE | ID: mdl-32631571
6.
Inhibition of Porcine Aminopeptidase M (pAMP) by the Pentapeptide Microginins.
Molecules
; 24(23)2019 Nov 29.
Article
in English
| MEDLINE | ID: mdl-31795383
7.
Correction to "Rational Design, Synthesis, and Mechanism of (3S,4R)-3-Amino-4-(difluoromethyl)cyclopent-1-ene-1-carboxylic Acid: Employing a Second-Deprotonation Strategy for Selectivity of Human Ornithine Aminotransferase over GABA Aminotransferase".
J Am Chem Soc
; 145(17): 9895-9896, 2023 May 03.
Article
in English
| MEDLINE | ID: mdl-37075548
8.
Correction to: Innovative Microemulsion Loaded with Unusual Dimeric Flavonoids from Fridericia platyphylla (Cham.) L.G. Lohmann Roots.
AAPS PharmSciTech
; 24(8): 227, 2023 Nov 14.
Article
in English
| MEDLINE | ID: mdl-37964166
9.
Identification, In Vitro Testing and Molecular Docking Studies of Microginins' Mechanism of Angiotensin-Converting Enzyme Inhibition.
Molecules
; 22(12)2017 Dec 05.
Article
in English
| MEDLINE | ID: mdl-29206156
10.
Exploring the conformational dynamics of the CRD4: a model for receptor lysosomal activity shifts in search of 'sweet' and 'sour' states.
J Biomol Struct Dyn
; : 1-7, 2023 Jul 13.
Article
in English
| MEDLINE | ID: mdl-37440242
11.
Covalent Inhibitors for Neglected Diseases: An Exploration of Novel Therapeutic Options.
Pharmaceuticals (Basel)
; 16(7)2023 Jul 19.
Article
in English
| MEDLINE | ID: mdl-37513939
12.
Dynamics of the personalities of PCSK9 on missense variants (rs505151 and rs562556) from elderly cohort studies in Brazil.
J Biomol Struct Dyn
; 41(24): 15625-15633, 2023.
Article
in English
| MEDLINE | ID: mdl-37010997
13.
Exploring the dark side of tertiary and quaternary structure dynamics in MtbFBPaseII.
J Biomol Struct Dyn
; : 1-9, 2023 Oct 14.
Article
in English
| MEDLINE | ID: mdl-37837432
14.
Trypanosoma cruzi Sirtuin 2 as a Relevant Druggable Target: New Inhibitors Developed by Computer-Aided Drug Design.
Pharmaceuticals (Basel)
; 16(3)2023 Mar 10.
Article
in English
| MEDLINE | ID: mdl-36986527
15.
LDLR missense variants disturb structural conformation and LDLR activity in T-lymphocytes of Familial hypercholesterolemia patients.
Gene
; 853: 147084, 2023 Feb 15.
Article
in English
| MEDLINE | ID: mdl-36464169
16.
Effects of PCSK9 missense variants on molecular conformation and biological activity in transfected HEK293FT cells.
Gene
; 851: 146979, 2023 Jan 30.
Article
in English
| MEDLINE | ID: mdl-36261084
17.
Identification of pathogenic variants in the Brazilian cohort with Familial hypercholesterolemia using exon-targeted gene sequencing.
Gene
; 875: 147501, 2023 Jul 30.
Article
in English
| MEDLINE | ID: mdl-37217153
18.
Inhibitor induced conformational changes in SARS-COV-2 papain-like protease.
Sci Rep
; 12(1): 11585, 2022 07 08.
Article
in English
| MEDLINE | ID: mdl-35803957
19.
Zika Virus NS2B-NS3 Protease: Quantum Chemical Properties Insights into Designing Inhibitory Peptides.
Protein Pept Lett
; 29(11): 901-910, 2022.
Article
in English
| MEDLINE | ID: mdl-36121092
20.
Carnitine palmitoyl transferase I: Conformational changes induced by long-chain fatty acyl CoA ligands.
J Mol Graph Model
; 112: 108125, 2022 05.
Article
in English
| MEDLINE | ID: mdl-35101729