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1.
BMJ Case Rep ; 17(1)2024 Jan 24.
Article in English | MEDLINE | ID: mdl-38272507

ABSTRACT

Our patient presented with complaints of progressive shortness of breath for 1 month. She was diagnosed with a case of infiltrative type of restrictive cardiomyopathy (RCM) based on echocardiography and cardiac MRI findings. Her fat pad biopsy was suggestive of AL type of amyloidosis (AL). She was diagnosed with a case of multiple myeloma (MM) based on bone marrow biopsy findings with 48% plasma cells and a skeletal survey with lytic bone lesions on the skull, thus meeting the Crab criteria. We want to highlight the complex nature of this case and the difficulties associated with making a diagnosis. This case report presents an excellent opportunity to touch on the interesting topics of RCM, amyloidosis and MM.


Subject(s)
Amyloidosis , Immunoglobulin Light-chain Amyloidosis , Multiple Myeloma , Female , Humans , Multiple Myeloma/complications , Multiple Myeloma/diagnosis , Multiple Myeloma/pathology , Immunoglobulin Light-chain Amyloidosis/complications , Immunoglobulin Light-chain Amyloidosis/diagnosis , Immunoglobulin Light-chain Amyloidosis/pathology , Amyloidosis/complications , Amyloidosis/diagnosis , Amyloidosis/pathology , Bone Marrow/pathology , Plasma Cells/pathology
2.
Cureus ; 16(8): e66416, 2024 Aug.
Article in English | MEDLINE | ID: mdl-39246977

ABSTRACT

Churg-Strauss syndrome is a rare multisystem disorder characterized by asthma, eosinophilia, and vasculitis. The patient presented with prolonged fever, cough with blood-stained sputum, weight loss, pain in the abdomen, and a subsequent onset of hoarseness of voice. A history of asthma, left-side vocal cord paralysis, eosinophilia, nodular opacities on radiography, and eosinophilic duodenitis on biopsy led to a diagnosis of Churg-Strauss syndrome. The patient's condition improved on treatment with steroids. This is an interesting case and presents an opportunity to learn about Churg-Strauss syndrome.

3.
BMJ Case Rep ; 16(7)2023 Jul 11.
Article in English | MEDLINE | ID: mdl-37433689

ABSTRACT

There has been a rapid increase in e-cigarette usage, especially among young adults. E-cigarettes are often thought to be a safe substitute to traditional smoking and are frequently used as a bridge to smoking cessation. E-cigarette or vaping product use-associated lung injury often presents with subacute or acute respiratory failure. We report a case of a young man in his 20s, who developed rapidly worsening respiratory failure in the postoperative period. This case highlights the importance of recognising this entity on time, especially in the perioperative period, and its impact on patient outcomes.


Subject(s)
Electronic Nicotine Delivery Systems , Lung Injury , Vaping , Male , Young Adult , Humans , Vaping/adverse effects , Postoperative Period , Risk Factors
4.
BMJ Case Rep ; 16(5)2023 May 31.
Article in English | MEDLINE | ID: mdl-37258052

ABSTRACT

A man had poor control of hypertension throughout 9 months of antituberculosis treatment. He consulted multiple physicians, who kept increasing this blood pressure medicine. Despite that, it was not controlled and he visited emergency many times with hypertensive urgency. When admitted in our care, he was off antituberculosis treatment for 5 days and his blood pressure was back to normal. We attributed it secondary to rifamipicin-induced enzyme induction. Tuberculosis and hypertension both being very common diseases, we report this case to highlight lack of awareness about these important and easily preventable drug interactions.


Subject(s)
Hypertension , Hypertensive Encephalopathy , Tuberculosis , Male , Humans , Rifampin/adverse effects , Tuberculosis/therapy , Hypertension/drug therapy , Blood Pressure , Antitubercular Agents
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