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Br J Dermatol ; 174(3): 629-32, 2016 Mar.
Article in English | MEDLINE | ID: mdl-26663358

ABSTRACT

Trichodysplasia spinulosa (TS) is a rare skin disease, caused by a specific polyomavirus, occurring in immunocompromised patients. The pathophysiological mechanisms of TS are not yet fully understood. By using polymerase chain reaction and skin biopsy immunostaining we report evidence, in a paediatric case, of follicular keratinocytes being the primary target of trichodysplasia spinulosa-associated polyomavirus.


Subject(s)
Opportunistic Infections/complications , Polyomavirus Infections/complications , Skin Diseases, Viral/complications , Child , Hair Diseases/pathology , Hair Diseases/virology , Hair Follicle/pathology , Hair Follicle/virology , Humans , Immunocompromised Host , Immunosuppressive Agents/adverse effects , Keratinocytes/virology , Male , Opportunistic Infections/pathology , Polyomavirus Infections/pathology
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