Search details
1.
Carotenoids from Starfish Patiria pectinifera: Therapeutic Activity in Models of Inflammatory Diseases.
Mar Drugs
; 21(9)2023 Aug 27.
Article
in English
| MEDLINE | ID: mdl-37755083
2.
Benfotiamine treatment activates the Nrf2/ARE pathway and is neuroprotective in a transgenic mouse model of tauopathy.
Hum Mol Genet
; 27(16): 2874-2892, 2018 08 15.
Article
in English
| MEDLINE | ID: mdl-29860433
3.
A screen for inducers of p21(waf1/cip1) identifies HIF prolyl hydroxylase inhibitors as neuroprotective agents with antitumor properties.
Neurobiol Dis
; 49: 13-21, 2013 Jan.
Article
in English
| MEDLINE | ID: mdl-22944173
4.
In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation.
J Neurosci Res
; 91(8): 1066-75, 2013 Aug.
Article
in English
| MEDLINE | ID: mdl-23456821
5.
Neurotoxic lupus autoantibodies alter brain function through two distinct mechanisms.
Proc Natl Acad Sci U S A
; 107(43): 18569-74, 2010 Oct 26.
Article
in English
| MEDLINE | ID: mdl-20921396
6.
Controlled enzymatic production of astrocytic hydrogen peroxide protects neurons from oxidative stress via an Nrf2-independent pathway.
Proc Natl Acad Sci U S A
; 107(40): 17385-90, 2010 Oct 05.
Article
in English
| MEDLINE | ID: mdl-20855618
7.
Degradation Kinetics of Disulfide Cross-Linked Microgels: Real-Time Monitoring by Confocal Microscopy.
Gels
; 9(10)2023 Sep 25.
Article
in English
| MEDLINE | ID: mdl-37888355
8.
Synthesis and Anti-Inflammatory Activity of 2-Amino-4,5,6,7-tetrahydrobenzo[b]thiophene-Derived NRF2 Activators.
ChemistryOpen
; 11(10): e202200181, 2022 10.
Article
in English
| MEDLINE | ID: mdl-36284193
9.
Structure-Activity Relationships and Transcriptomic Analysis of Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors.
Antioxidants (Basel)
; 11(2)2022 Jan 24.
Article
in English
| MEDLINE | ID: mdl-35204103
10.
Challenges and Limitations of Targeting the Keap1-Nrf2 Pathway for Neurotherapeutics: Bach1 De-Repression to the Rescue.
Front Aging Neurosci
; 13: 673205, 2021.
Article
in English
| MEDLINE | ID: mdl-33897412
11.
Identification of a potent Nrf2 displacement activator among aspirin-containing prodrugs.
Neurochem Int
; 149: 105148, 2021 10.
Article
in English
| MEDLINE | ID: mdl-34329734
12.
HIF Prolyl Hydroxylase Inhibitors for COVID-19 Treatment: Pros and Cons.
Front Pharmacol
; 11: 621054, 2020.
Article
in English
| MEDLINE | ID: mdl-33584306
13.
"Branched Tail" Oxyquinoline Inhibitors of HIF Prolyl Hydroxylase: Early Evaluation of Toxicity and Metabolism Using Liver-on-a-chip.
Drug Metab Lett
; 13(1): 45-52, 2019.
Article
in English
| MEDLINE | ID: mdl-30488807
14.
L-ascorbic acid: A true substrate for HIF prolyl hydroxylase?
Biochimie
; 147: 46-54, 2018 Apr.
Article
in English
| MEDLINE | ID: mdl-29289682
15.
Activation of Nrf2 and Hypoxic Adaptive Response Contribute to Neuroprotection Elicited by Phenylhydroxamic Acid Selective HDAC6 Inhibitors.
ACS Chem Neurosci
; 9(5): 894-900, 2018 05 16.
Article
in English
| MEDLINE | ID: mdl-29338172
16.
The status of Nrf2-based therapeutics: current perspectives and future prospects.
Neural Regen Res
; 11(11): 1708-1711, 2016 Nov.
Article
in English
| MEDLINE | ID: mdl-28123399
17.
Bioactive Flavonoids and Catechols as Hif1 and Nrf2 Protein Stabilizers - Implications for Parkinson's Disease.
Aging Dis
; 7(6): 745-762, 2016 Dec.
Article
in English
| MEDLINE | ID: mdl-28053825
18.
Targeting Nrf2-mediated gene transcription by extremely potent synthetic triterpenoids attenuate dopaminergic neurotoxicity in the MPTP mouse model of Parkinson's disease.
Antioxid Redox Signal
; 18(2): 139-57, 2013 Jan 10.
Article
in English
| MEDLINE | ID: mdl-22746536
19.
Development of Neh2-luciferase reporter and its application for high throughput screening and real-time monitoring of Nrf2 activators.
Chem Biol
; 18(6): 752-65, 2011 Jun 24.
Article
in English
| MEDLINE | ID: mdl-21700211
20.
Utilization of an in vivo reporter for high throughput identification of branched small molecule regulators of hypoxic adaptation.
Chem Biol
; 17(4): 380-91, 2010 Apr 23.
Article
in English
| MEDLINE | ID: mdl-20416509