ABSTRACT
Lentigo maligna (LM) is a subtype of lentiginous melanoma confined to the epidermis, which is associated with chronic sun exposure. Its clinical, dermatoscopic, and histopathological diagnosis can be challenging, particularly in the early and advanced stages, requiring appropriate clinicopathological correlation. This article reviews the clinical presentation, diagnosis through noninvasive methods (dermoscopy and confocal microscopy), and provides insights for diagnosis of extrafacial LM through the presentation of four representative clinical cases from different phases of a theoretical-practical progression model. Recognizing these lesions is crucial, as once they invade the dermis, they can behave like any other type of melanoma.
Subject(s)
Dermoscopy , Hutchinson's Melanotic Freckle , Microscopy, Confocal , Skin Neoplasms , Humans , Hutchinson's Melanotic Freckle/pathology , Hutchinson's Melanotic Freckle/diagnosis , Microscopy, Confocal/methods , Skin Neoplasms/pathology , Skin Neoplasms/diagnosis , Dermoscopy/methods , Female , Male , Aged , Middle Aged , Disease Progression , Aged, 80 and overABSTRACT
We describe a case of genital ulcer and inguinal adenopathies that were attributable to monkeypox virus infection. We suggest clinicians adopt a low threshold for suspicion, particularly when evaluating genital ulcer disease.