Search | Virtual Health Library

1.

Acquisition of epithelial plasticity in human chronic liver disease.

Gribben, Christopher; Galanakis, Vasileios; Calderwood, Alexander; Williams, Eleanor C; Chazarra-Gil, Ruben; Larraz, Miguel; Frau, Carla; Puengel, Tobias; Guillot, Adrien; Rouhani, Foad J; Mahbubani, Krishnaa; Godfrey, Edmund; Davies, Susan E; Athanasiadis, Emmanouil; Saeb-Parsy, Kourosh; Tacke, Frank; Allison, Michael; Mohorianu, Irina; Vallier, Ludovic.

Nature ; 630(8015): 166-173, 2024 Jun.

Article in English | MEDLINE | ID: mdl-38778114

2.

Auto-aggressive CXCR6⁺ CD8 T cells cause liver immune pathology in NASH.

Dudek, Michael; Pfister, Dominik; Donakonda, Sainitin; Filpe, Pamela; Schneider, Annika; Laschinger, Melanie; Hartmann, Daniel; Hüser, Norbert; Meiser, Philippa; Bayerl, Felix; Inverso, Donato; Wigger, Jennifer; Sebode, Marcial; Öllinger, Rupert; Rad, Roland; Hegenbarth, Silke; Anton, Martina; Guillot, Adrien; Bowman, Andrew; Heide, Danijela; Müller, Florian; Ramadori, Pierluigi; Leone, Valentina; Garcia-Caceres, Cristina; Gruber, Tim; Seifert, Gabriel; Kabat, Agnieszka M; Mallm, Jan-Philipp; Reider, Simon; Effenberger, Maria; Roth, Susanne; Billeter, Adrian T; Müller-Stich, Beat; Pearce, Edward J; Koch-Nolte, Friedrich; Käser, Rafael; Tilg, Herbert; Thimme, Robert; Boettler, Tobias; Tacke, Frank; Dufour, Jean-Francois; Haller, Dirk; Murray, Peter J; Heeren, Ron; Zehn, Dietmar; Böttcher, Jan P; Heikenwälder, Mathias; Knolle, Percy A.

Nature ; 592(7854): 444-449, 2021 04.

Article in English | MEDLINE | ID: mdl-33762736

3.

Inhibition of LTßR signalling activates WNT-induced regeneration in lung.

Conlon, Thomas M; John-Schuster, Gerrit; Heide, Danijela; Pfister, Dominik; Lehmann, Mareike; Hu, Yan; Ertüz, Zeynep; Lopez, Martin A; Ansari, Meshal; Strunz, Maximilian; Mayr, Christoph; Angelidis, Ilias; Ciminieri, Chiara; Costa, Rita; Kohlhepp, Marlene Sophia; Guillot, Adrien; Günes, Gizem; Jeridi, Aicha; Funk, Maja C; Beroshvili, Giorgi; Prokosch, Sandra; Hetzer, Jenny; Verleden, Stijn E; Alsafadi, Hani; Lindner, Michael; Burgstaller, Gerald; Becker, Lore; Irmler, Martin; Dudek, Michael; Janzen, Jakob; Goffin, Eric; Gosens, Reinoud; Knolle, Percy; Pirotte, Bernard; Stoeger, Tobias; Beckers, Johannes; Wagner, Darcy; Singh, Indrabahadur; Theis, Fabian J; de Angelis, Martin Hrabé; O'Connor, Tracy; Tacke, Frank; Boutros, Michael; Dejardin, Emmanuel; Eickelberg, Oliver; Schiller, Herbert B; Königshoff, Melanie; Heikenwalder, Mathias; Yildirim, Ali Önder.

Nature ; 588(7836): 151-156, 2020 12.

Article in English | MEDLINE | ID: mdl-33149305

4.

C-C chemokine receptor type 7 (CCR7) regulates hepatic CD8 + T cell homeostasis and response to acute liver injury.

Niemietz, Patricia; Peiseler, Moritz; Kohlhepp, Marlene; Horn, Paul; Matchett, Kylie; Wang, Yuting; Haas, Leon; Zhang, Tianjiao; Bruneau, Alix; Guillot, Adrien; Berger, Hilmar; Liepelt, Anke; Warzecha, Klaudia; Demske, Catharina; Möckel, Diana; Lammers, Twan; Henderson, Neil; Heymann, Felix; Tacke, Frank.

Hepatology ; 2024 Jan 17.

Article in English | MEDLINE | ID: mdl-38231043

5.

Intestinal retinol saturase is implicated in the development of obesity and epithelial homeostasis upon injury.

Kiefer, Marie F; Meng, Yueming; Yang, Na; Vahrenbrink, Madita; Wulff, Sascha; Li, Chen; Wowro, Sylvia J; Petricek, Konstantin M; Sommerfeld, Manuela; Flores, Roberto E; Obermayer, Benedikt; Piepelow, Karolin; Klaus, Susanne; Hartl, Kimberly; Guillot, Adrien; Tacke, Frank; Sigal, Michael; Schupp, Michael.

Am J Physiol Endocrinol Metab ; 2024 Jun 19.

Article in English | MEDLINE | ID: mdl-38895981

6.

Angiocrine signaling in sinusoidal homeostasis and liver diseases.

Gao, Jinhang; Lan, Tian; Kostallari, Enis; Guo, Yangkun; Lai, Enjiang; Guillot, Adrien; Ding, Bisen; Tacke, Frank; Tang, Chengwei; Shah, Vijay H.

J Hepatol ; 2024 May 17.

Article in English | MEDLINE | ID: mdl-38763358

7.

Mapping the hepatic immune landscape identifies monocytic macrophages as key drivers of steatohepatitis and cholangiopathy progression.

Guillot, Adrien; Winkler, Marc; Silva Afonso, Milessa; Aggarwal, Abhishek; Lopez, David; Berger, Hilmar; Kohlhepp, Marlene S; Liu, Hanyang; Özdirik, Burcin; Eschrich, Johannes; Ma, Jing; Peiseler, Moritz; Heymann, Felix; Pendem, Swetha; Mahadevan, Sangeetha; Gao, Bin; Diehl, Lauri; Gupta, Ruchi; Tacke, Frank.

Hepatology ; 78(1): 150-166, 2023 07 01.

Article in English | MEDLINE | ID: mdl-36630995

8.

CDK4/6 inhibition enhances T-cell immunotherapy on hepatocellular carcinoma cells by rejuvenating immunogenicity.

Cai, Xiurong; Yin, Guo; Chen, Shuai; Tacke, Frank; Guillot, Adrien; Liu, Hanyang.

Cancer Cell Int ; 24(1): 215, 2024 Jun 20.

Article in English | MEDLINE | ID: mdl-38902716

9.

Macrophages in cholangiopathies.

Bruneau, Alix; Guillot, Adrien; Tacke, Frank.

Curr Opin Gastroenterol ; 38(2): 114-120, 2022 03 01.

Article in English | MEDLINE | ID: mdl-35098932

10.

Publisher Correction: Inhibition of LTßR signalling activates WNT-induced regeneration in lung.

Conlon, Thomas M; John-Schuster, Gerrit; Heide, Danijela; Pfister, Dominik; Lehmann, Mareike; Hu, Yan; Ertüz, Zeynep; Lopez, Martin A; Ansari, Meshal; Strunz, Maximilian; Mayr, Christoph; Angelidis, Ilias; Ciminieri, Chiara; Costa, Rita; Kohlhepp, Marlene Sophia; Guillot, Adrien; Günes, Gizem; Jeridi, Aicha; Funk, Maja C; Beroshvili, Giorgi; Prokosch, Sandra; Hetzer, Jenny; Verleden, Stijn E; Alsafadi, Hani; Lindner, Michael; Burgstaller, Gerald; Becker, Lore; Irmler, Martin; Dudek, Michael; Janzen, Jakob; Goffin, Eric; Gosens, Reinoud; Knolle, Percy; Pirotte, Bernard; Stoeger, Tobias; Beckers, Johannes; Wagner, Darcy; Singh, Indrabahadur; Theis, Fabian J; de Angelis, Martin Hrabé; O'Connor, Tracy; Tacke, Frank; Boutros, Michael; Dejardin, Emmanuel; Eickelberg, Oliver; Schiller, Herbert B; Königshoff, Melanie; Heikenwalder, Mathias; Yildirim, Ali Önder.

Nature ; 589(7842): E6, 2021 Jan.

Article in English | MEDLINE | ID: mdl-33353984

11.

Author Correction: Auto-aggressive CXCR6⁺ CD8 T cells cause liver immune pathology in NASH.

Dudek, Michael; Pfister, Dominik; Donakonda, Sainitin; Filpe, Pamela; Schneider, Annika; Laschinger, Melanie; Hartmann, Daniel; Hüser, Norbert; Meiser, Philippa; Bayerl, Felix; Inverso, Donato; Wigger, Jennifer; Sebode, Marcial; Öllinger, Rupert; Rad, Roland; Hegenbarth, Silke; Anton, Martina; Guillot, Adrien; Bowman, Andrew; Heide, Danijela; Müller, Florian; Ramadori, Pierluigi; Leone, Valentina; Garcia-Caceres, Cristina; Gruber, Tim; Seifert, Gabriel; Kabat, Agnieszka M; Mallm, Jan-Philipp; Reider, Simon; Effenberger, Maria; Roth, Susanne; Billeter, Adrian T; Müller-Stich, Beat; Pearce, Edward J; Koch-Nolte, Friedrich; Käser, Rafael; Tilg, Herbert; Thimme, Robert; Boettler, Tobias; Tacke, Frank; Dufour, Jean-Francois; Haller, Dirk; Murray, Peter J; Heeren, Ron; Zehn, Dietmar; Böttcher, Jan P; Heikenwälder, Mathias; Knolle, Percy A.

Nature ; 593(7860): E14, 2021 May.

Article in English | MEDLINE | ID: mdl-33972788

12.

Targeting liver aldehyde dehydrogenase-2 prevents heavy but not moderate alcohol drinking.

Guillot, Adrien; Ren, Tianyi; Jourdan, Tony; Pawlosky, Robert J; Han, Elaine; Kim, Seung-Jin; Zhang, Li; Koob, George F; Gao, Bin.

Proc Natl Acad Sci U S A ; 116(51): 25974-25981, 2019 12 17.

Article in English | MEDLINE | ID: mdl-31792171

13.

Nuclear Receptors Linking Metabolism, Inflammation, and Fibrosis in Nonalcoholic Fatty Liver Disease.

Puengel, Tobias; Liu, Hanyang; Guillot, Adrien; Heymann, Felix; Tacke, Frank; Peiseler, Moritz.

Int J Mol Sci ; 23(5)2022 Feb 28.

Article in English | MEDLINE | ID: mdl-35269812

14.

Differential effects of selective- and pan-PPAR agonists on experimental steatohepatitis and hepatic macrophages^â.

Lefere, Sander; Puengel, Tobias; Hundertmark, Jana; Penners, Christian; Frank, Anna Katharina; Guillot, Adrien; de Muynck, Kevin; Heymann, Felix; Adarbes, Vanessa; Defrêne, Evelyne; Estivalet, Céline; Geerts, Anja; Devisscher, Lindsey; Wettstein, Guillaume; Tacke, Frank.

J Hepatol ; 73(4): 757-770, 2020 10.

Article in English | MEDLINE | ID: mdl-32360434

15.

MicroRNA-223 Ameliorates Nonalcoholic Steatohepatitis and Cancer by Targeting Multiple Inflammatory and Oncogenic Genes in Hepatocytes.

He, Yong; Hwang, Seonghwan; Cai, Yan; Kim, Seung-Jin; Xu, Mingjiang; Yang, Dingcheng; Guillot, Adrien; Feng, Dechun; Seo, Wonhyo; Hou, Xin; Gao, Bin.

Hepatology ; 70(4): 1150-1167, 2019 10.

Article in English | MEDLINE | ID: mdl-30964207

16.

Adipocyte Death Preferentially Induces Liver Injury and Inflammation Through the Activation of Chemokine (C-C Motif) Receptor 2-Positive Macrophages and Lipolysis.

Kim, Seung-Jin; Feng, Dechun; Guillot, Adrien; Dai, Shen; Liu, Fengming; Hwang, Seonghwan; Parker, Richard; Seo, Wonhyo; He, Yong; Godlewski, Grzegorz; Jeong, Won-Il; Lin, Yuhong; Qin, Xuebin; Kunos, George; Gao, Bin.

Hepatology ; 69(5): 1965-1982, 2019 05.

Article in English | MEDLINE | ID: mdl-30681731

17.

Alcohol inhibits T-cell glucose metabolism and hepatitis in ALDH2-deficient mice and humans: roles of acetaldehyde and glucocorticoids.

Gao, Yanhang; Zhou, Zhou; Ren, Tianyi; Kim, Seung-Jin; He, Yong; Seo, Wonhyo; Guillot, Adrien; Ding, Yanhua; Wu, Ruihong; Shao, Shuang; Wang, Xiaomei; Zhang, Hong; Wang, Wei; Feng, Dechun; Xu, Mingjiang; Han, Elaine; Zhong, Wei; Zhou, Zhanxiang; Pacher, Pal; Niu, Junqi; Gao, Bin.

Gut ; 68(7): 1311-1322, 2019 07.

Article in English | MEDLINE | ID: mdl-30121625

18.

ALDH2 deficiency promotes alcohol-associated liver cancer by activating oncogenic pathways via oxidized DNA-enriched extracellular vesicles.

Seo, Wonhyo; Gao, Yanhang; He, Yong; Sun, Jing; Xu, Hongqin; Feng, Dechun; Park, Seol Hee; Cho, Young-Eun; Guillot, Adrien; Ren, Tianyi; Wu, Ruihong; Wang, Jingyun; Kim, Seung-Jin; Hwang, Seonghwan; Liangpunsakul, Suthat; Yang, Yingzi; Niu, Junqi; Gao, Bin.

J Hepatol ; 71(5): 1000-1011, 2019 11.

Article in English | MEDLINE | ID: mdl-31279903

19.

Disruption of Renal Arginine Metabolism Promotes Kidney Injury in Hepatorenal Syndrome in Mice.

Varga, Zoltan V; Erdelyi, Katalin; Paloczi, Janos; Cinar, Resat; Zsengeller, Zsuzsanna K; Jourdan, Tony; Matyas, Csaba; Nemeth, Balazs Tamas; Guillot, Adrien; Xiang, Xiaogang; Mehal, Adam; Haskó, György; Stillman, Isaac E; Rosen, Seymour; Gao, Bin; Kunos, George; Pacher, Pal.

Hepatology ; 68(4): 1519-1533, 2018 10.

Article in English | MEDLINE | ID: mdl-29631342

20.

Reply to Brewer: Liver-targeted ALDH2 inhibition may reduce alcohol-seeking behaviors with limited side effects.

Guillot, Adrien; Koob, George F; Gao, Bin.

Proc Natl Acad Sci U S A ; 117(14): 7573-7574, 2020 04 07.

Article in English | MEDLINE | ID: mdl-32127485

Virtual Health Library

United States - Mexico Border

Your selection (0)

Export format:

Export: