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Pathol Biol (Paris) ; 62(4): 209-11, 2014 Aug.
Article in French | MEDLINE | ID: mdl-24973857

ABSTRACT

In this report, we address the issue of allogeneic stem cell transplantation in children with congenital neutropenia. Constitutional disorders with neutropenia are exceptional. Treatment and prevention of severe infections are a major concern in the management of chronic neutropenia. These disorders, especially Kostmann's disease and Shwachman-Bodian-Diamond syndrome, are associated with an increased risk of leukemia. The role of allogeneic stem cell transplantation in these patients is still unclear. In an effort to harmonize clinical practices between different French transplantation centers, the French Society of Bone Marrow Transplantation and Cell Therapy (SFGM-TC) set up the fourth annual series of workshops which brought together practitioners from all member centers and took place in September 2013 in Lille.


Subject(s)
Neutropenia/congenital , Neutropenia/surgery , Stem Cell Transplantation/methods , Transplantation, Homologous/methods , Adolescent , Bone Marrow Diseases/complications , Bone Marrow Diseases/surgery , Child , Child, Preschool , Congenital Bone Marrow Failure Syndromes , Exocrine Pancreatic Insufficiency/complications , Exocrine Pancreatic Insufficiency/surgery , France , Humans , Infant , Infections , Leukemia , Lipomatosis/complications , Lipomatosis/surgery , Neutropenia/complications , Risk Factors , Shwachman-Diamond Syndrome , Stem Cell Transplantation/standards , Transplantation, Homologous/standards
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