ABSTRACT
The possible mechanisms of clinical efficacy "sleeve" gastrectomy in patients with obe- sity were analysed. The metabolic effect transactions associated not only with reducing the volume of the stomach, but the acceleration passage of gastric contents of the tube and the small intestinp_
Subject(s)
Cytoreduction Surgical Procedures/methods , Gastrectomy/methods , Obesity, Morbid/surgery , Stomach/surgery , Adult , Contrast Media/metabolism , Female , Gastric Mucosa/metabolism , Gastrointestinal Transit , Humans , Male , Middle Aged , Obesity, Morbid/diagnostic imaging , Obesity, Morbid/metabolism , Obesity, Morbid/pathology , Radiography , Stomach/diagnostic imaging , Stomach/pathologyABSTRACT
Pathogenetic peculiarities of chronic intraabdominal hypertension syndrome (CHIHS) in patients, suffering morbid obesity (MO), to whom bariatric operative interventions were performed, were studied. The intraabdominal pressure factor impact on the concurrent diseases and postoperative period course in patients, suffering MO, was analyzed.
Subject(s)
Bariatric Surgery/methods , Intra-Abdominal Hypertension/complications , Obesity, Morbid/surgery , Adolescent , Adult , Body Mass Index , Cardiovascular Physiological Phenomena , Female , Humans , Intra-Abdominal Hypertension/diagnosis , Intra-Abdominal Hypertension/physiopathology , Intra-Abdominal Hypertension/surgery , Male , Middle Aged , Monitoring, Ambulatory , Monitoring, Intraoperative , Obesity, Morbid/complications , Obesity, Morbid/diagnosis , Obesity, Morbid/physiopathology , Respiratory Physiological Phenomena , Treatment Outcome , Young AdultABSTRACT
In 2009 in the clinic a biliopancreatic shunting operation with duodenal switch was performed in accordance to D. Hess-P. Marceau method in 26 patients, suffering morbid obesity. First clinical results of operative intervention (the fixed terms of follow-up for 6 months after the operation) were studied in 15 patients. The main complications, the impact of operative intervention on the course of comorbidities, associated with obesity, diseases and metabolic disorders, were analyzed.
Subject(s)
Biliopancreatic Diversion/methods , Diabetes Mellitus/surgery , Duodenum/surgery , Dyslipidemias/surgery , Gastroesophageal Reflux/surgery , Hypertension/surgery , Obesity, Morbid/surgery , Adult , Biliary Tract , Body Mass Index , Body Weight , Diabetes Complications , Diabetes Mellitus/pathology , Dyslipidemias/complications , Dyslipidemias/pathology , Female , Follow-Up Studies , Gastroesophageal Reflux/complications , Gastroesophageal Reflux/pathology , Humans , Hypertension/complications , Hypertension/pathology , Male , Middle Aged , Obesity, Morbid/complications , Obesity, Morbid/pathology , Severity of Illness Index , Treatment OutcomeABSTRACT
The results of surgical treatment of 69 patients, suffering impassability of the gut hollow organs, were analyzed. There was established, that, while presence of intraabdominal hypertension, an early postoperative complications rate is increasing trustworthily. Intraabdominal pressure (IAP) raising, coexistent with intraabdominal postoperative complications presence, constitutes a prognostic factor, proving the presence of necessity to perform relaparotomy. Hospital lethality risk is determined by value of intraabdominal perfusion pressure. Results of the investigation witnesses the necessity to conduct a systemic monitoring of IAP in patients, suffering impassability of the gut hollow organs.
Subject(s)
Abdomen/surgery , Compartment Syndromes/etiology , Gastrointestinal Diseases/surgery , Postoperative Complications/etiology , APACHE , Abdomen/physiopathology , Adult , Aged , Aged, 80 and over , Compartment Syndromes/surgery , Decompression, Surgical , Female , Gastrointestinal Diseases/complications , Gastrointestinal Diseases/physiopathology , Humans , Male , Middle Aged , Monitoring, Physiologic , Perfusion , Postoperative Complications/surgery , Pressure , Prognosis , ReoperationABSTRACT
In experiment on 50 white mongrel male rats there were investigated postoperative morphological changes in the area of a potential formation of colorectal anastomosis, occurring after total rectal mobilization performance. There was established, that rectal mobilization, even while securing a blood flow along the main vessels, causes nonreversible ischemic disorders in its wall. The investigation results witness the enhanced risk of the sutures insufficiency occurrence in low colorectal anastomoses and substantiate the expediency of application of prophylactic methods for this complication in a clinical practice.
Subject(s)
Colon , Ischemia/prevention & control , Suture Techniques , Anastomosis, Surgical/adverse effects , Anastomosis, Surgical/methods , Animals , Colon/blood supply , Colon/pathology , Colon/surgery , Intestinal Mucosa/blood supply , Intestinal Mucosa/pathology , Intestinal Mucosa/surgery , Ischemia/etiology , Ischemia/physiopathology , Male , Microcirculation , Necrosis , RatsABSTRACT
The influence of intraabdominal hypertension on polyorgan insufficiency and bacterial translocation formation was studied in experiment on 40 white male rats owing mass about 250-300 g. Intraabdominal pressure (IAP) raising in the rats causes abdominal ischemia and consequent early changes in anterior abdominal wall muscles, small intestine and large bowel, kidneys, spleen, liver, and bacterial.translocation as well. The results of investigation trusts the necessity of monitoring and IAP effective control conduction in surgical patients.
Subject(s)
Abdominal Cavity , Bacterial Translocation , Compartment Syndromes/complications , Multiple Organ Failure/etiology , Abdominal Cavity/microbiology , Abdominal Cavity/physiopathology , Animals , Compartment Syndromes/microbiology , Compartment Syndromes/pathology , Disease Models, Animal , Male , Manometry , Multiple Organ Failure/microbiology , Multiple Organ Failure/pathology , Pressure , RatsABSTRACT
Anastomositis and abdominal cavity infiltrate constitutes the most frequent early inflammatory complications, occurring after gastrointestinal operations. The informativity of diagnostic methods of these complications, the volume and efficacy of conservative curative procedures were shown. Introduction of antihomotoxic preparations in complex of treatment measures, in part, of Traumeel C, Lymphomyosot, Mucosa compositum C, Echinacea compositum C had promoted the efficacy raising and the shortening of the treatment duration of these complications.