Search details
1.
The Parkinson's disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability.
Cell
; 185(12): 2035-2056.e33, 2022 06 09.
Article
in English
| MEDLINE | ID: mdl-35688132
2.
Specification of Physiologic and Disease States by Distinct Proteins and Protein Conformations.
Cell
; 171(5): 1001-1014, 2017 Nov 16.
Article
in English
| MEDLINE | ID: mdl-29149602
3.
Widespread macromolecular interaction perturbations in human genetic disorders.
Cell
; 161(3): 647-660, 2015 Apr 23.
Article
in English
| MEDLINE | ID: mdl-25910212
4.
Toward the quantification of α-synuclein aggregates with digital seed amplification assays.
Proc Natl Acad Sci U S A
; 121(3): e2312031121, 2024 Jan 16.
Article
in English
| MEDLINE | ID: mdl-38194461
5.
Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations.
Cell
; 146(2): 318-31, 2011 Jul 22.
Article
in English
| MEDLINE | ID: mdl-21757228
6.
Role of the repeat expansion size in predicting age of onset and severity in RFC1 disease.
Brain
; 147(5): 1887-1898, 2024 May 03.
Article
in English
| MEDLINE | ID: mdl-38193360
7.
Toward More Accessible Fully Automated 3D Volumetric MRI Decision Trees for the Differential Diagnosis of Multiple System Atrophy, Related Disorders, and Age-Matched Healthy Subjects.
Cerebellum
; 22(6): 1098-1108, 2023 Dec.
Article
in English
| MEDLINE | ID: mdl-36156185
8.
Case 20-2021: A 69-Year-Old Man with Ataxia.
N Engl J Med
; 385(2): 165-175, 2021 Jul 08.
Article
in English
| MEDLINE | ID: mdl-34233100
9.
Modelling neurodegeneration in Saccharomyces cerevisiae: why cook with baker's yeast?
Nat Rev Neurosci
; 11(6): 436-49, 2010 06.
Article
in English
| MEDLINE | ID: mdl-20424620
10.
From yeast to patient neurons and back again: powerful new discovery platform.
Mov Disord
; 29(10): 1231-40, 2014 Sep.
Article
in English
| MEDLINE | ID: mdl-25131316
11.
Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo.
Nat Cell Biol
; 9(2): 139-48, 2007 Feb.
Article
in English
| MEDLINE | ID: mdl-17187063
12.
Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons.
Sci Adv
; 10(6): eadj4767, 2024 Feb 09.
Article
in English
| MEDLINE | ID: mdl-38335281
13.
The spectrum of neurological presentation in individuals affected by TBL1XR1 gene defects.
Orphanet J Rare Dis
; 19(1): 79, 2024 Feb 20.
Article
in English
| MEDLINE | ID: mdl-38378692
14.
Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies.
bioRxiv
; 2024 Mar 07.
Article
in English
| MEDLINE | ID: mdl-38496508
15.
Lysosomal dysfunction promotes cleavage and neurotoxicity of tau in vivo.
PLoS Genet
; 6(7): e1001026, 2010 Jul 15.
Article
in English
| MEDLINE | ID: mdl-20664788
16.
AAGGG repeat expansions trigger RFC1-independent synaptic dysregulation in human CANVAS Neurons.
bioRxiv
; 2023 Dec 14.
Article
in English
| MEDLINE | ID: mdl-38168171
17.
A pesticide and iPSC dopaminergic neuron screen identifies and classifies Parkinson-relevant pesticides.
Nat Commun
; 14(1): 2803, 2023 05 16.
Article
in English
| MEDLINE | ID: mdl-37193692
18.
Health phenome of Parkinson's patients reveals prominent mood-sleep cluster.
Res Sq
; 2023 Dec 22.
Article
in English
| MEDLINE | ID: mdl-38196602
19.
Patient-derived three-dimensional cortical neurospheres to model Parkinson's disease.
PLoS One
; 17(12): e0277532, 2022.
Article
in English
| MEDLINE | ID: mdl-36454869
20.
A Brain-Penetrant Stearoyl-CoA Desaturase Inhibitor Reverses α-Synuclein Toxicity.
Neurotherapeutics
; 19(3): 1018-1036, 2022 04.
Article
in English
| MEDLINE | ID: mdl-35445353