Search | Virtual Health Library

1.

Functional genomic landscape of cancer-intrinsic evasion of killing by T cells.

Lawson, Keith A; Sousa, Cristovão M; Zhang, Xiaoyu; Kim, Eiru; Akthar, Rummy; Caumanns, Joseph J; Yao, Yuxi; Mikolajewicz, Nicholas; Ross, Catherine; Brown, Kevin R; Zid, Abdelrahman Abou; Fan, Zi Peng; Hui, Shirley; Krall, Jordan A; Simons, Donald M; Slater, Chloe J; De Jesus, Victor; Tang, Lujia; Singh, Richa; Goldford, Joshua E; Martin, Sarah; Huang, Qian; Francis, Elizabeth A; Habsid, Andrea; Climie, Ryan; Tieu, David; Wei, Jiarun; Li, Ren; Tong, Amy Hin Yan; Aregger, Michael; Chan, Katherine S; Han, Hong; Wang, Xiaowei; Mero, Patricia; Brumell, John H; Finelli, Antonio; Ailles, Laurie; Bader, Gary; Smolen, Gromoslaw A; Kingsbury, Gillian A; Hart, Traver; Kung, Charles; Moffat, Jason.

Nature ; 586(7827): 120-126, 2020 10.

Article in English | MEDLINE | ID: mdl-32968282

2.

HumanNet v3: an improved database of human gene networks for disease research.

Kim, Chan Yeong; Baek, Seungbyn; Cha, Junha; Yang, Sunmo; Kim, Eiru; Marcotte, Edward M; Hart, Traver; Lee, Insuk.

Nucleic Acids Res ; 50(D1): D632-D639, 2022 01 07.

Article in English | MEDLINE | ID: mdl-34747468

3.

AR-negative prostate cancer is vulnerable to loss of JMJD1C demethylase.

Yoshihama, Yohei; LaBella, Kyle A; Kim, Eiru; Bertolet, Lori; Colic, Medina; Li, Jiexi; Shang, Xiaoying; Wu, Chang-Jiun; Spring, Denise J; Wang, Y Alan; Hart, Traver; DePinho, Ronald A.

Proc Natl Acad Sci U S A ; 118(36)2021 09 07.

Article in English | MEDLINE | ID: mdl-34475205

4.

BiomeNet: a database for construction and analysis of functional interaction networks for any species with a sequenced genome.

Kim, Eiru; Bae, Dasom; Yang, Sunmo; Ko, Gunhwan; Lee, Sungho; Lee, Byungwook; Lee, Insuk.

Bioinformatics ; 36(5): 1584-1589, 2020 03 01.

Article in English | MEDLINE | ID: mdl-31599923

5.

HumanNet v2: human gene networks for disease research.

Hwang, Sohyun; Kim, Chan Yeong; Yang, Sunmo; Kim, Eiru; Hart, Traver; Marcotte, Edward M; Lee, Insuk.

Nucleic Acids Res ; 47(D1): D573-D580, 2019 01 08.

Article in English | MEDLINE | ID: mdl-30418591

6.

SoyNet: a database of co-functional networks for soybean Glycine max.

Kim, Eiru; Hwang, Sohyun; Lee, Insuk.

Nucleic Acids Res ; 45(D1): D1082-D1089, 2017 01 04.

Article in English | MEDLINE | ID: mdl-27492285

7.

COEXPEDIA: exploring biomedical hypotheses via co-expressions associated with medical subject headings (MeSH).

Yang, Sunmo; Kim, Chan Yeong; Hwang, Sohyun; Kim, Eiru; Kim, Hyojin; Shim, Hongseok; Lee, Insuk.

Nucleic Acids Res ; 45(D1): D389-D396, 2017 01 04.

Article in English | MEDLINE | ID: mdl-27679477

8.

MouseNet v2: a database of gene networks for studying the laboratory mouse and eight other model vertebrates.

Kim, Eiru; Hwang, Sohyun; Kim, Hyojin; Shim, Hongseok; Kang, Byunghee; Yang, Sunmo; Shim, Jae Ho; Shin, Seung Yeon; Marcotte, Edward M; Lee, Insuk.

Nucleic Acids Res ; 44(D1): D848-54, 2016 Jan 04.

Article in English | MEDLINE | ID: mdl-26527726

9.

AraNet v2: an improved database of co-functional gene networks for the study of Arabidopsis thaliana and 27 other nonmodel plant species.

Lee, Tak; Yang, Sunmo; Kim, Eiru; Ko, Younhee; Hwang, Sohyun; Shin, Junha; Shim, Jung Eun; Shim, Hongseok; Kim, Hyojin; Kim, Chanyoung; Lee, Insuk.

Nucleic Acids Res ; 43(Database issue): D996-1002, 2015 Jan.

Article in English | MEDLINE | ID: mdl-25355510

10.

FlyNet: a versatile network prioritization server for the Drosophila community.

Shin, Junha; Yang, Sunmo; Kim, Eiru; Kim, Chan Yeong; Shim, Hongseok; Cho, Ara; Kim, Hyojin; Hwang, Sohyun; Shim, Jung Eun; Lee, Insuk.

Nucleic Acids Res ; 43(W1): W91-7, 2015 Jul 01.

Article in English | MEDLINE | ID: mdl-25943544

11.

MORPHIN: a web tool for human disease research by projecting model organism biology onto a human integrated gene network.

Hwang, Sohyun; Kim, Eiru; Yang, Sunmo; Marcotte, Edward M; Lee, Insuk.

Nucleic Acids Res ; 42(Web Server issue): W147-53, 2014 Jul.

Article in English | MEDLINE | ID: mdl-24861622

12.

YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae.

Kim, Hanhae; Shin, Junha; Kim, Eiru; Kim, Hyojin; Hwang, Sohyun; Shim, Jung Eun; Lee, Insuk.

Nucleic Acids Res ; 42(Database issue): D731-6, 2014 Jan.

Article in English | MEDLINE | ID: mdl-24165882

13.

JiffyNet: a web-based instant protein network modeler for newly sequenced species.

Kim, Eiru; Kim, Hanhae; Lee, Insuk.

Nucleic Acids Res ; 41(Web Server issue): W192-7, 2013 Jul.

Article in English | MEDLINE | ID: mdl-23685435

14.

Dynamic rewiring of biological activity across genotype and lineage revealed by context-dependent functional interactions.

Kim, Eiru; Novak, Lance C; Lin, Chenchu; Colic, Medina; Bertolet, Lori L; Gheorghe, Veronica; Bristow, Christopher A; Hart, Traver.

Genome Biol ; 23(1): 140, 2022 06 29.

Article in English | MEDLINE | ID: mdl-35768873

15.

Improved analysis of CRISPR fitness screens and reduced off-target effects with the BAGEL2 gene essentiality classifier.

Kim, Eiru; Hart, Traver.

Genome Med ; 13(1): 2, 2021 01 06.

Article in English | MEDLINE | ID: mdl-33407829

16.

Discovery of putative tumor suppressors from CRISPR screens reveals rewired lipid metabolism in acute myeloid leukemia cells.

Lenoir, W Frank; Morgado, Micaela; DeWeirdt, Peter C; McLaughlin, Megan; Griffith, Audrey L; Sangree, Annabel K; Feeley, Marissa N; Esmaeili Anvar, Nazanin; Kim, Eiru; Bertolet, Lori L; Colic, Medina; Dede, Merve; Doench, John G; Hart, Traver.

Nat Commun ; 12(1): 6506, 2021 11 11.

Article in English | MEDLINE | ID: mdl-34764293

17.

Multiplex enCas12a screens detect functional buffering among paralogs otherwise masked in monogenic Cas9 knockout screens.

Dede, Merve; McLaughlin, Megan; Kim, Eiru; Hart, Traver.

Genome Biol ; 21(1): 262, 2020 10 15.

Article in English | MEDLINE | ID: mdl-33059726

18.

A network of human functional gene interactions from knockout fitness screens in cancer cells.

Kim, Eiru; Dede, Merve; Lenoir, Walter F; Wang, Gang; Srinivasan, Sanjana; Colic, Medina; Hart, Traver.

Life Sci Alliance ; 2(2)2019 04.

Article in English | MEDLINE | ID: mdl-30979825

19.

All for One, and One for All.

Kim, Eiru; Hart, Traver.

Cell Syst ; 5(4): 314-316, 2017 10 25.

Article in English | MEDLINE | ID: mdl-29073370

20.

Network-Based Gene Function Prediction in Mouse and Other Model Vertebrates Using MouseNet Server.

Kim, Eiru; Lee, Insuk.

Methods Mol Biol ; 1611: 183-198, 2017.

Article in English | MEDLINE | ID: mdl-28451980

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