Search details
1.
Expansion of the Cosmetics Europe skin sensitisation database with new substances and PPRA data.
Regul Toxicol Pharmacol
; 131: 105169, 2022 Jun.
Article
in English
| MEDLINE | ID: mdl-35447229
2.
Read-across and new approach methodologies applied in a 10-step framework for cosmetics safety assessment - A case study with parabens.
Regul Toxicol Pharmacol
; 132: 105161, 2022 Jul.
Article
in English
| MEDLINE | ID: mdl-35508214
3.
The Threshold of Toxicological Concern (TTC) is a pragmatic tool for the safety assessment: Case studies of cosmetic ingredients with low consumer exposure.
Regul Toxicol Pharmacol
; 123: 104964, 2021 Jul.
Article
in English
| MEDLINE | ID: mdl-34023455
4.
New framework for a non-animal approach adequately assures the safety of cosmetic ingredients - A case study on caffeine.
Regul Toxicol Pharmacol
; 123: 104931, 2021 Jul.
Article
in English
| MEDLINE | ID: mdl-33905778
5.
Development of a next generation risk assessment framework for the evaluation of skin sensitisation of cosmetic ingredients.
Regul Toxicol Pharmacol
; 116: 104721, 2020 Oct.
Article
in English
| MEDLINE | ID: mdl-32645429
6.
Use of human liver and EpiSkin™ S9 subcellular fractions as a screening assays to compare the in vitro hepatic and dermal metabolism of 47 cosmetics-relevant chemicals.
J Appl Toxicol
; 40(3): 416-433, 2020 03.
Article
in English
| MEDLINE | ID: mdl-31912921
7.
Comparison of the metabolism of 10 cosmetics-relevant chemicals in EpiSkin™ S9 subcellular fractions and in vitro human skin explants.
J Appl Toxicol
; 40(2): 313-326, 2020 02.
Article
in English
| MEDLINE | ID: mdl-31701564
8.
Measurement of the penetration of 56 cosmetic relevant chemicals into and through human skin using a standardized protocol.
J Appl Toxicol
; 40(3): 403-415, 2020 03.
Article
in English
| MEDLINE | ID: mdl-31867769
9.
Dermal absorption study OECD TG 428 mass balance recommendations based on the EFSA database.
Regul Toxicol Pharmacol
; 108: 104475, 2019 Nov.
Article
in English
| MEDLINE | ID: mdl-31539567
10.
Challenges in working towards an internal threshold of toxicological concern (iTTC) for use in the safety assessment of cosmetics: Discussions from the Cosmetics Europe iTTC Working Group workshop.
Regul Toxicol Pharmacol
; 103: 63-72, 2019 Apr.
Article
in English
| MEDLINE | ID: mdl-30653989
11.
Use of a Simple in vitro Test to Assess Loss of Chemical due to Volatility during an in vitro Human Skin Absorption Study.
Skin Pharmacol Physiol
; 32(3): 117-124, 2019.
Article
in English
| MEDLINE | ID: mdl-30889606
12.
Non-animal methods to predict skin sensitization (II): an assessment of defined approaches *.
Crit Rev Toxicol
; 48(5): 359-374, 2018 05.
Article
in English
| MEDLINE | ID: mdl-29474122
13.
Non-animal methods to predict skin sensitization (I): the Cosmetics Europe database.
Crit Rev Toxicol
; 48(5): 344-358, 2018 05.
Article
in English
| MEDLINE | ID: mdl-29474128
14.
Cosmetics Europe compilation of historical serious eye damage/eye irritation in vivo data analysed by drivers of classification to support the selection of chemicals for development and evaluation of alternative methods/strategies: the Draize eye test Reference Database (DRD).
Arch Toxicol
; 91(2): 521-547, 2017 Feb.
Article
in English
| MEDLINE | ID: mdl-26997338
15.
Comparison of the Skin Penetration of 3 Metabolically Stable Chemicals Using Fresh and Frozen Human Skin.
Skin Pharmacol Physiol
; 30(5): 234-245, 2017.
Article
in English
| MEDLINE | ID: mdl-28746940
16.
Response to "OECD 428 in vitro dermal absorption mass balance performance based on our in-house database of pesticide studies".
Regul Toxicol Pharmacol
; 115: 104707, 2020 08.
Article
in English
| MEDLINE | ID: mdl-32512117
17.
N-terminally truncated forms of human cathepsin F accumulate in aggresome-like inclusions.
Biochim Biophys Acta
; 1833(10): 2254-66, 2013 Oct.
Article
in English
| MEDLINE | ID: mdl-23684953
18.
Cysteine cathepsins are not critical for TNF-alpha-induced cell death in T98G and U937 cells.
Biochim Biophys Acta
; 1794(9): 1372-7, 2009 Sep.
Article
in English
| MEDLINE | ID: mdl-19409515
19.
Partition coefficient and diffusion coefficient determinations of 50 compounds in human intact skin, isolated skin layers and isolated stratum corneum lipids.
Toxicol In Vitro
; 69: 104990, 2020 Dec.
Article
in English
| MEDLINE | ID: mdl-32882340
20.
A mode-of-action ontology model for safety evaluation of chemicals: Outcome of a series of workshops on repeated dose toxicity.
Toxicol In Vitro
; 59: 44-50, 2019 Sep.
Article
in English
| MEDLINE | ID: mdl-30954655