[Correction of urodynamic disorders in women with obstructive urination].

From a position of urodynamic evaluation, obstructive urination represents a violation of the phase of urinary bladder emptying. The study was aimed to evaluation of urodynamic parameters in women with obstructive urination on a background of conservative treatment. The study included 40 women with obstructive urination aged 26 to 72 years. All patients received alpha-adrenoblocker Omnic Okas (tamsulosin) at a dose 0.4 mg once a day in the morning for 3 months. Initially, a visual assessment of uroflougramm revealed curves tipical for the obstructive type of urination. Quantitative parameters showed a decrease in the maximum urine flow rate and lengthening the time of urination. Treatment with alpha-adrenoblocker contributed to shortening the time of urination, and increased maximum urine flow rate. Before treatment, ultrasound examination revealed the presence of residual urine volume of 60-210 mL (mean 129 ml) after urination in 32 (80%) patients. After treatment, presence of residual urine volume of 50-90 ml (mean 65 ml) was noted only in 9 (22.5%) patients. It is concluded that the selective alpha-adrenoblocker Omnic-Okas neutralizes the effect mediated by alpha-adrenoceptors in the area of the bladder neck and proximal urethra, and contribute to the normal detrusor contraction, and therefore, eliminates the functional obstruction, while significantly improving the quality of life of patients.

[Current approaches to the treatment of non-gonococcal urethritis in men].

The study was made of 50 men suffering from non-gonococcal urethritis caused by mixed pathogenic and opportunistic urogenital infection. Clinical characteristics of urethritis in relation to infection pathogen are shown. The results of clinical and laboratory examinations were considered in choice of antibacterial therapy. Safocid, a combined antibacterial medicine, demonstrated its clinical and microbiological efficacy in the treatment of patients with non-gonococcal urethritis of mixed etiology.

[Efficacy of combined physiotherapeutic methods in complex treatment of patients with chronic infectious urethroprostatitis].

The study is aimed at investigation of efficacy and safety of a combined effect of laser therapy and vibromagnetotherapy in complex treatment of patients with chronic urethroprostatitis in the presence of sexually transmitted infection (STI). A total of 35 males aged 20 to 51 years entered the study. They were divided into 3 groups. Group 1 received standard basic therapy, group 2 received basic and laser therapy, group 3 - basic treatment and laser plus vibromagnetotherapy. Effectiveness of the treatment was assessed by the evidence obtained from clinical, bacteriological, device and functional examinations. The results of the treatments were evaluated after 2 weeks of the follow-up. It is shown that patients of groups 2 and 3 achieved more pronounced improvement of clinical and laboratory indices, parameters of basal blood flow. Thus, physiotherapy, added to antibacterial treatment, is safe and effective in the treatment of chronic urethroprostatitis and STI.

[Combined treatment of complicated chlamydial infection in males with ozone therapy].

Urogenital chlamydial monoinfection was diagnosed in 127 males using enzyme immunoassay, polymerase chain reaction, transrectal ultrasound examination of the prostatic gland. Of them, 72 patients had chronic urethroprostatitis. Microhemodynamics of these patients was studied with laser doppler flowmetry of the prostate and urethra. The patients received etiotropic therapy with fromilide, regional transurethral and transrectal ozone therapy. The symptoms relieved in 4-6 weeks. Repeated enzyme immunoassay and polymerase chain reaction stated elimination of the infective agent. Improvement of hemodynamics and urethral, prostatic microcirculation was stated after administration of regional ozone therapy.

[Efficacy of low-intensity laser radiation and antibacterial therapy in the treatment of chronic prostatitis in the presence of sexually transmitted infections].

We studied 94 patients with chronic prostatitis (CP) in combination with urogenital chlamydiasis. The patients were divided into three groups. Group 1 consisted of 32 patients with bacterial prostatitis and sexually transmitted infection (STI). They were treated with fromilid in a dose 500 mg twice a day. Group 2 (n = 27) received also low-intensity laser radiation (LILR) on the prostatic gland. Group 3 patients (n = 35) with abacterial prostatitis were given fromilid (500 mg twice a day). We studied prostatic hemodynamics with color doppler mapping. A specific feature of prostatic vascularisation in CP and STI versus healthy subjects is heterogeneous decline of vessels density in ischemic zones with parallel decrease in these vessels diameter. A peripheral prostatic zone in CP patients with STI was characterized by lower vascularisation than central one. This deteriorates the course of the disease. The results of the study show that adjuvant LILR in CP patients with STI raises efficacy of therapy by 11%. Investigation of prostate vascularisation and hemodynamics of its vessels in CP patients with STI using transrectal ultrasonography and dopplerography provide detailed information about prostatic structure allowing for lesion zones. This facilitates choice of an optimal complex treatment with application of LELR in peripheral inflammation of the prostate.