Search details
1.
Antiviral Properties of HIV-1 Capsid Inhibitor GSK878.
Antimicrob Agents Chemother
; 67(5): e0169422, 2023 05 17.
Article
in English
| MEDLINE | ID: mdl-37039636
2.
GSK3640254 Is a Novel HIV-1 Maturation Inhibitor with an Optimized Virology Profile.
Antimicrob Agents Chemother
; 66(1): e0187621, 2022 01 18.
Article
in English
| MEDLINE | ID: mdl-34780263
3.
Impact of Integrase Sequences from HIV-1 Subtypes A6/A1 on the In Vitro Potency of Cabotegravir or Rilpivirine.
Antimicrob Agents Chemother
; 66(3): e0170221, 2022 03 15.
Article
in English
| MEDLINE | ID: mdl-34978890
4.
Week 96 Genotypic and Phenotypic Results of the Fostemsavir Phase 3 BRIGHTE Study in Heavily Treatment-Experienced Adults Living with Multidrug-Resistant HIV-1.
Antimicrob Agents Chemother
; 66(6): e0175121, 2022 06 21.
Article
in English
| MEDLINE | ID: mdl-35502922
5.
Scaffold modifications to the 4-(4,4-dimethylpiperidinyl) 2,6-dimethylpyridinyl class of HIV-1 allosteric integrase inhibitors.
Bioorg Med Chem
; 67: 116833, 2022 08 01.
Article
in English
| MEDLINE | ID: mdl-35605346
6.
The Genesis and Future Prospects of Small Molecule HIV-1 Attachment Inhibitors.
Adv Exp Med Biol
; 1366: 45-64, 2022.
Article
in English
| MEDLINE | ID: mdl-35412134
7.
Prevalence of gp160 polymorphisms known to be related to decreased susceptibility to temsavir in different subtypes of HIV-1 in the Los Alamos National Laboratory HIV Sequence Database.
J Antimicrob Chemother
; 76(11): 2958-2964, 2021 10 11.
Article
in English
| MEDLINE | ID: mdl-34297843
8.
Susceptibility of global HIV-1 clinical isolates to fostemsavir using the PhenoSense® Entry assay.
J Antimicrob Chemother
; 76(3): 648-652, 2021 02 11.
Article
in English
| MEDLINE | ID: mdl-33241285
9.
Design and exploration of C-3 benzoic acid bioisosteres and alkyl replacements in the context of GSK3532795 (BMS-955176) that exhibit broad spectrum HIV-1 maturation inhibition.
Bioorg Med Chem Lett
; 36: 127823, 2021 03 15.
Article
in English
| MEDLINE | ID: mdl-33508465
10.
GSK3732394: a Multi-specific Inhibitor of HIV Entry.
J Virol
; 93(20)2019 10 15.
Article
in English
| MEDLINE | ID: mdl-31375580
11.
Design, synthesis and SAR study of novel C2-pyrazolopyrimidine amides and amide isosteres as allosteric integrase inhibitors.
Bioorg Med Chem Lett
; 30(21): 127516, 2020 11 01.
Article
in English
| MEDLINE | ID: mdl-32860982
12.
Heterocycle amide isosteres: An approach to overcoming resistance for HIV-1 integrase strand transfer inhibitors.
Bioorg Med Chem Lett
; 30(3): 126784, 2020 02 01.
Article
in English
| MEDLINE | ID: mdl-31761656
13.
Structure-based amelioration of PXR transactivation in a novel series of macrocyclic allosteric inhibitors of HIV-1 integrase.
Bioorg Med Chem Lett
; 30(22): 127531, 2020 11 15.
Article
in English
| MEDLINE | ID: mdl-32890685
14.
Design, synthesis and SAR study of bridged tricyclic pyrimidinone carboxamides as HIV-1 integrase inhibitors.
Bioorg Med Chem
; 28(13): 115541, 2020 07 01.
Article
in English
| MEDLINE | ID: mdl-32389483
15.
A Novel gp41-Binding Adnectin with Potent Anti-HIV Activity Is Highly Synergistic when Linked to a CD4-Binding Adnectin.
J Virol
; 92(14)2018 07 15.
Article
in English
| MEDLINE | ID: mdl-29743355
16.
Mechanistic Studies and Modeling Reveal the Origin of Differential Inhibition of Gag Polymorphic Viruses by HIV-1 Maturation Inhibitors.
PLoS Pathog
; 12(11): e1005990, 2016 Nov.
Article
in English
| MEDLINE | ID: mdl-27893830
17.
The discovery and preclinical evaluation of BMS-707035, a potent HIV-1 integrase strand transfer inhibitor.
Bioorg Med Chem Lett
; 28(12): 2124-2130, 2018 07 01.
Article
in English
| MEDLINE | ID: mdl-29779976
18.
The design, synthesis and structure-activity relationships associated with C28 amine-based betulinic acid derivatives as inhibitors of HIV-1 maturation.
Bioorg Med Chem Lett
; 28(9): 1550-1557, 2018 05 15.
Article
in English
| MEDLINE | ID: mdl-29631960
19.
Antiviral Activity, Safety, and Exposure-Response Relationships of GSK3532795, a Second-Generation Human Immunodeficiency Virus Type 1 Maturation Inhibitor, Administered as Monotherapy or in Combination With Atazanavir With or Without Ritonavir in a Phase 2a Randomized, Dose-Ranging, Controlled Trial (AI468002).
Clin Infect Dis
; 65(3): 442-452, 2017 Aug 01.
Article
in English
| MEDLINE | ID: mdl-28369211
20.
Discovery and Characterization of a Novel CD4-Binding Adnectin with Potent Anti-HIV Activity.
Antimicrob Agents Chemother
; 61(8)2017 08.
Article
in English
| MEDLINE | ID: mdl-28584151