[Immunological reactivity of patients with suppurative lung diseases and the effectiveness of immunocorrective therapy]. / Immunologicheskaia reaktivnost' u bol'nykh nagnoitel'nymi zabolevaniiami legkikh i éffektivnost' immunokorrigiruiushchei terapii.

Patients with acute lung abscesses and bronchiectatic diseases manifested deep changes in the immune responsiveness, which were largely of compensatory (elevation of IgA content to over 2 mg/ml), immunosuppressive (decrease of lymphocyte blast transformation with PHA down to 52.2 and 48.6%) or autoimmune (increase of spontaneous lymphocyte blast transformation up to 8%) character. In patients with acute lung abscesses, the indicators enumerated tended during treatment toward normalization which was not over in the majority of them by the discharge from hospital. In patients with bronchiectatic disease, that tendency was observable only after additional treatment with immunocorrective drugs (levamisole, splenin).

[Comparative characteristics of immunologic indices in patients with lung abscesses and viral hepatitis]. / Sravnitel'naia kharakteristika nekotorykh immunologicheskikh pokazatelei u bol'nykh s abtsessami legkikh i virusnym gepatitom.

A study of the immunological status in 52 patients with acute and 20 patients with chronic abscesses of the lungs, 86 patients with viral hepatitis revealed disorders of the immunological reactivity of a quantitative character with monotypic immune response. In autoimmune disorders it is necessary to carry out immunocorrection. In chronic forms immunocorrection should be considered the main treatment method.

[Status of immunological reactivity in workers engaged in the production of thiourea, ammonium rhodanate and cobalt and manganese salts]. / Sostoianie immunnoi reaktivnosti rabochikh proizvodstva tiomocheviny, rodanistogo ammoniia, solei kobal'ta i magrantsa.

The proposed study of the immunologic reactivity state in chemical plant workers revealed humoral and cellular reactivity changes caused by chemical agents and the workers' immunologic background. It was established that cobalt and manganese salts caused initial immune response.

[The value of determining antibodies to DNA in patients with purulent diseases of the lungs]. / Znachenie opredeleniia antitel k DNK u bol'nykh s nagnoitel'nymi zabolevaniiami legkikh.

Anti-DNA antibody titers are elevated in the patients with purulent diseases of the lungs and antibodies to nDNA appear that are undetectable in normal subjects. These data correlate with the inflammatory process activity in the lungs, with the diameter of the decayed cavity, disease duration, and efficacy of therapy. Dynamic titration of antibodies to DNA (particularly nDNA) over the course of the disease appears to be an important prognostic test reflecting the stability of autoimmune impairments and the efficacy of the therapeutic scheme used in the treatment of patients with purulent diseases of the lungs.