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1.
Support Care Cancer ; 26(8): 2801-2807, 2018 Aug.
Article in English | MEDLINE | ID: mdl-29508139

ABSTRACT

BACKGROUND: Surgical procedure for breast cancer is not without its side effects and one such side effect is axillary web syndrome (AWS), characterized by palpable fibrotic-like cords in the operated arm. As physical evaluation is the only gold standard method used, our study aims to assess the incidence and early detection of AWS with a self-assessment questionnaire. METHODS: From July 2013 to July 2014, 370 breast cancer patients were enrolled. AWS incidence was 51.1%, with 94.1% onset in the first 4 weeks after surgery; 43.5% of the patients did not recover in the first 8 weeks. Univariate analysis showed that BMI (P < 0.001), age (P < 0.001), educational level (P = 0.01), and exercise frequency in the eighth week of follow-up (P < 0.001) were significantly associated with the AWS detection, and multivariate analyses confirmed that younger patients (age < 50) have significantly higher AWS detection (OR = 2.38 (95%CI 1.53, 3.71) and that BMI is associated with AWS, with normal weight patients (BMI ≤ 25) having a significantly greater AWS detection with an odds ratio of 2.11 (95%CI 1.33, 3.36). CONCLUSION: Our findings indicated that the incidence of AWS is high in breast cancer patients, particularly in the first month after surgery. Not all patients achieved recovery during our 8 week follow-up, suggesting that evaluation and treatment should be longer. Double AWS detection was found for patients who were younger (age < 50) and with normal weight.


Subject(s)
Axilla/pathology , Breast Neoplasms/surgery , Adult , Aged , Cohort Studies , Female , Humans , Incidence , Middle Aged , Prospective Studies , Surveys and Questionnaires , Syndrome
2.
Radiol Med ; 118(1): 112-22, 2013 Feb.
Article in English | MEDLINE | ID: mdl-22744343

ABSTRACT

PURPOSE: This study aimed to evaluate the diagnostic possibilities of MR arthrography in the correct identification of complex tears of the biceps pulley and their possible correlation with anterosuperior impingement (ASI) development. MATERIALS AND METHODS: MR arthrography examinations of 23 athletes with clinical suspicion of ASI were reviewed. All examinations were obtained with a 1.5-T unit (Signa Horizon, GE Healthcare). The shoulders were studied with a dedicated surface coil with the patient's arm in the neutral position and in internal and external rotation. In five patients, images in abduction-external rotation (ABER) were obtained. Within 2 month after MR arthrography, the athletes underwent arthroscopic surgery. RESULTS: MR arthrography images showed a spectrum of tears that, according to the Habermeyer classification, were subdivided into four groups: type 1 in three patients; type 2 in five; type 3 in seven; type 4 in eight. At arthroscopic evaluation, one patient presented type 1 lesion, five type 2, five type 3 and ten type 4. During arthroscopic dynamic manoeuvres, ASI signs were observed in three patients with type 3 lesion and in ten with type 4 lesion. CONCLUSIONS: MR arthrography is the imaging modality of choice for evaluating lesions of the rotator interval structures, and only complex lesions of the biceps pulley are related to the development of ASI.


Subject(s)
Athletic Injuries/complications , Athletic Injuries/diagnosis , Magnetic Resonance Imaging/methods , Shoulder Impingement Syndrome/diagnosis , Shoulder Impingement Syndrome/etiology , Tendon Injuries/diagnosis , Tendon Injuries/etiology , Adolescent , Adult , Arthroscopy , Athletic Injuries/surgery , Female , Humans , Male , Shoulder Impingement Syndrome/surgery , Tendon Injuries/surgery
3.
Eur Rev Med Pharmacol Sci ; 21(3): 460-469, 2017 02.
Article in English | MEDLINE | ID: mdl-28239826

ABSTRACT

OBJECTIVE: To evaluate the current management of carpal tunnel syndrome (CTS) at a national level. PATIENTS AND METHODS: A multicentric observational study was conducted in 34 Italian centers by specialists participating in the Management of Peripheral Neuropathies Study Group on 377 patients (age, mean±SD 56±14.4 years, 73.2% females) with CTS. The characteristics of the disease and its management were recorded at baseline and during a 2-month follow-up using a standardized clinical record and assessed with validated clinical tests. RESULTS: A wide variability in the interventions prescribed and classified according to three categories (physical, pharmacological and neurotrophic therapies) was evident. A subgroup of 303 patients was treated with a combination of neurotrophic agents containing alpha-lipoic acid (ALA). At the end of the follow-up, a general improvement in symptoms and functional impairment was observed, with a significant reduction in BCTQ (Boston Carpal Tunnel Questionnaire) (p<0.001) and in NRS (Pain Numeric Rating Scale, p<0.001 for both nocturnal and diurnal pain). CONCLUSIONS: An appropriate approach to CTS implies a multimodal and multidisciplinary management, involving several specialists and using a variety of conservative interventions. Conservative (physical and pharmacological) interventions can provide a clinical improvement in patients with CTS.


Subject(s)
Carpal Tunnel Syndrome/diagnosis , Surveys and Questionnaires , Adult , Aged , Carpal Tunnel Syndrome/therapy , Female , Humans , Italy , Male , Middle Aged , Physical Therapy Modalities , Thioctic Acid/therapeutic use
4.
Breast ; 27: 78-86, 2016 Jun.
Article in English | MEDLINE | ID: mdl-27054752

ABSTRACT

OBJECTIVES: The latissimus dorsi (LD) flap is well-known in breast reconstruction especially in previously-irradiated patients, in order to have a low capsular contraction rate whenever an implant is associated. The aim of this study is to closely evaluate the effect of LD flap harvesting on shoulder function as well as specific movements related to the LD, both objectively and subjectively. MATERIALS AND METHODS: We retrospectively collected data on 86 patients who underwent pedicled LD muscle flap for breast reconstruction at the European Institute of Oncology between September 1995 until March 2011. RESULTS: The majority of patients showed a joint recovery superior to 80% in all joint movements examined. Disabilities of the Arm, Shoulder and Hand questionnaire revealed minimal disability similar to normal range and furthermore it appears to decrease in all sports and in particular in those who practice with LD involvement. CONCLUSION: Focusing this data, a growing, "disability-free" percentage changes depending on whether or not the patients have practiced sport could be appreciate.


Subject(s)
Joint Diseases/physiopathology , Mammaplasty/adverse effects , Postoperative Complications , Shoulder Joint/physiopathology , Surgical Flaps/adverse effects , Adult , Aged , Breast Neoplasms/physiopathology , Breast Neoplasms/surgery , Disability Evaluation , Female , Humans , Joint Diseases/etiology , Mammaplasty/methods , Middle Aged , Prospective Studies , Range of Motion, Articular , Retrospective Studies , Superficial Back Muscles/transplantation
5.
Am J Surg ; 181(1): 50-1, 2001 Jan.
Article in English | MEDLINE | ID: mdl-11248176

ABSTRACT

Implant of a bovine-derived vascular bioprosthesis as arterio-venous shunt for hemodialysis may raise some problems regarding tunnel fashioning. Therefore, we have proposed a simple "tube-guided" technique to make implant safer and to avoid complications.


Subject(s)
Bioprosthesis , Blood Vessel Prosthesis Implantation , Renal Dialysis , Animals , Arteriovenous Shunt, Surgical/methods , Blood Vessel Prosthesis , Blood Vessel Prosthesis Implantation/methods , Cattle , Forearm/blood supply , Humans , Prosthesis Design
6.
Ann Ital Chir ; 74(1): 97-101, 2003.
Article in Italian | MEDLINE | ID: mdl-12870288

ABSTRACT

Splenic artery aneurysm presented with rupture is an unusual and potentially deadly reason of intraperitoneal hemorrhage. There are a lot of pathogenetic hypothesis; timing according to disease severity and surgical choices aren't definitely codified authors present one patient with hemoperitoneum for ruptured splenic artery aneurysm affected by chronic lymphatic leukaemia too and review international literature; they underline pathogenesis, symptoms, preoperative investigations and therapy. Degeneration of the media, atherosclerotic changes and high blood flow due to pregnancy and portal hypertension could be the main pathogenetic factors. Ultrasonography is the first investigation we have to practice if we suspect hemoperitoneum. We can practice computed tomography and angiography too if cardiovascular condition are good. Rupture showing acute abdominal pain and cardiovascular collapse suggest strongly urgent operation. The choice of operation is determined by location of the aneurysm. When located in the distal third of the splenic artery, the aneurysm is resected with spleen; alternatively, when it is located in prossimal third we can perform conservative operation.


Subject(s)
Aneurysm, Ruptured/pathology , Aneurysm, Ruptured/surgery , Splenic Artery/pathology , Splenic Artery/surgery , Aged , Humans , Male
7.
Neuroradiol J ; 25(5): 569-74, 2012 Nov.
Article in English | MEDLINE | ID: mdl-24029092

ABSTRACT

Rosai-Dorfman disease (RDD) was firstly described in 1969 as a benign proliferative disorder of histiocytes with systemic symptoms and lymphadenopathy. This disease is of uncertain pathogenesis and mostly occurs in children and young adults. The typical clinical features of RDD include bilateral painless cervical lymphadenopathy, but extranodal involvement may also be present. The most common extranodal sites include organs such as the respiratory tract, skin, nasal cavity, orbit and bone. Isolated central nervous system (CNS) manifestations are extremely rare. In case of CNS involvement, the commonest imaging findings are dural-based extra-axial enhancing masses. We describe a case of intracranial RDD mimicking multiple meningiomas both clinically and radiologically in a 57-year-old man presenting with a six-year history of progressive right visual and hearing loss and tinnitus. In cases of multiple extra-axial lesions it is worth bearing in mind the possible differential diagnosis for intracranial RDD and eventually propose to the patient further investigations.

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