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Adv Gerontol ; 31(6): 958-965, 2018.
Article in Russian | MEDLINE | ID: mdl-30877828

ABSTRACT

We have previously shown that carotenoids increase lifespan of model organisms Drosophila melanogaster and Caenorhabditis elegans. In the present study, we investigated the effects of cloudberry extract, an abundant food for people in North, with a relatively large carotenoid content on Drosophila melanogaster lifespan parameters and resistance to different stress conditions. It was shown that the cloudberry extract increased the median lifespan and the age of 90% mortality of females up to 11-19%. The rate of aging was decreased up to 13%. The effects of cloudberry extract on lifespan of males were less expressed. In some cases, they were even negative. The extract had no effects on males and females' resistance to starvation. However, it decreased the resistance of males to oxidative stress.


Subject(s)
Drosophila melanogaster/drug effects , Longevity/drug effects , Oxidative Stress/drug effects , Plant Extracts/pharmacology , Animals , Female , Male , Sex Factors , Starvation
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