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1.

Two regulatory T cell populations in the visceral adipose tissue shape systemic metabolism.

Torres, Santiago Valle; Man, Kevin; Elmzzahi, Tarek; Malko, Darya; Chisanga, David; Liao, Yang; Prout, Melanie; Abbott, Caitlin A; Tang, Adelynn; Wu, Jian; Becker, Matthias; Mason, Teisha; Haynes, Vanessa; Tsui, Carlson; Shakiba, Mehrnoush Hadaddzadeh; Hamada, Doaa; Britt, Kara; Groom, Joanna R; McColl, Shaun R; Shi, Wei; Watt, Matthew J; Le Gros, Graham; Pal, Bhupinder; Beyer, Marc; Vasanthakumar, Ajithkumar; Kallies, Axel.

Nat Immunol ; 25(3): 496-511, 2024 Mar.

Article in English | MEDLINE | ID: mdl-38356058

2.

Homeostatic IL-13 in healthy skin directs dendritic cell differentiation to promote T_H2 and inhibit T_H17 cell polarization.

Mayer, Johannes U; Hilligan, Kerry L; Chandler, Jodie S; Eccles, David A; Old, Samuel I; Domingues, Rita G; Yang, Jianping; Webb, Greta R; Munoz-Erazo, Luis; Hyde, Evelyn J; Wakelin, Kirsty A; Tang, Shiau-Choot; Chappell, Sally C; von Daake, Sventja; Brombacher, Frank; Mackay, Charles R; Sher, Alan; Tussiwand, Roxane; Connor, Lisa M; Gallego-Ortega, David; Jankovic, Dragana; Le Gros, Graham; Hepworth, Matthew R; Lamiable, Olivier; Ronchese, Franca.

Nat Immunol ; 22(12): 1538-1550, 2021 12.

Article in English | MEDLINE | ID: mdl-34795444

3.

Comment on: Repositioning T_H cell polarization from single cytokines to complex help.

Jankovic, Dragana; Ciucci, Thomas; Coffman, Robert L; Coquet, Jonathan M; Le Gros, Graham; Mosmann, Tim R; Sher, Alan; Ronchese, Franca.

Nat Immunol ; 23(4): 501-502, 2022 04.

Article in English | MEDLINE | ID: mdl-35190720

4.

Author Correction: Homeostatic IL-13 in healthy skin directs dendritic cell differentiation to promote T_H2 and inhibit T_H17 cell polarization.

Mayer, Johannes U; Hilligan, Kerry L; Chandler, Jodie S; Eccles, David A; Old, Samuel I; Domingues, Rita G; Yang, Jianping; Webb, Greta R; Munoz-Erazo, Luis; Hyde, Evelyn J; Wakelin, Kirsty A; Tang, Shiau-Choot; Chappell, Sally C; von Daake, Sventja; Brombacher, Frank; Mackay, Charles R; Sher, Alan; Tussiwand, Roxane; Connor, Lisa M; Gallego-Ortega, David; Jankovic, Dragana; Le Gros, Graham; Hepworth, Matthew R; Lamiable, Olivier; Ronchese, Franca.

Nat Immunol ; 23(6): 985, 2022 Jun.

Article in English | MEDLINE | ID: mdl-35418649

5.

New Zealand's science-led response to the SARS-CoV-2 pandemic.

Geoghegan, Jemma L; Moreland, Nicole J; Le Gros, Graham; Ussher, James E.

Nat Immunol ; 22(3): 262-263, 2021 03.

Article in English | MEDLINE | ID: mdl-33627881

6.

Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells.

Roediger, Ben; Kyle, Ryan; Yip, Kwok Ho; Sumaria, Nital; Guy, Thomas V; Kim, Brian S; Mitchell, Andrew J; Tay, Szun S; Jain, Rohit; Forbes-Blom, Elizabeth; Chen, Xi; Tong, Philip L; Bolton, Holly A; Artis, David; Paul, William E; Fazekas de St Groth, Barbara; Grimbaldeston, Michele A; Le Gros, Graham; Weninger, Wolfgang.

Nat Immunol ; 14(6): 564-73, 2013 Jun.

Article in English | MEDLINE | ID: mdl-23603794

7.

STAT6 tunes maximum T cell IL-4 production from stochastically regulated Il4 alleles.

Kyle, Ryan L; Prout, Melanie; Le Gros, Graham; Robinson, Marcus J.

Immunol Cell Biol ; 102(3): 194-211, 2024 Mar.

Article in English | MEDLINE | ID: mdl-38286436

8.

Modulation of intestinal epithelial permeability by chronic small intestinal helminth infections.

Mules, Thomas C; Tang, Jeffry S; Vacca, Francesco; Yumnam, Bibek; Schmidt, Alfonso; Lavender, Brittany; Maclean, Kate; Noble, Sophia-Louise; Waugh, Craig; van Ginkel, Roel; Camberis, Mali; Le Gros, Graham; Inns, Stephen.

Immunol Cell Biol ; 102(5): 396-406, 2024.

Article in English | MEDLINE | ID: mdl-38648862

9.

Diverse innate stimuli activate basophils through pathways involving Syk and IκB kinases.

Pellefigues, Christophe; Mehta, Palak; Chappell, Sally; Yumnam, Bibek; Old, Sam; Camberis, Mali; Le Gros, Graham.

Proc Natl Acad Sci U S A ; 118(12)2021 03 23.

Article in English | MEDLINE | ID: mdl-33727419

10.

Immunity without innate lymphoid cells.

Weinkove, Robert; Filbey, Kara; Le Gros, Graham.

Nat Immunol ; 17(11): 1237-1238, 2016 10 19.

Article in English | MEDLINE | ID: mdl-27760103

11.

Helminths' therapeutic potential to treat intestinal barrier dysfunction.

Mules, Thomas C; Inns, Stephen; Le Gros, Graham.

Allergy ; 78(11): 2892-2905, 2023 11.

Article in English | MEDLINE | ID: mdl-37449458

12.

BCL6 deletion in CD4 T cells does not affect Th2 effector mediated immunity in the skin.

Chandler, Jodie; Prout, Melanie; Old, Sam; Morgan, Cynthia; Ronchese, Franca; Benoist, Christophe; Le Gros, Graham.

Immunol Cell Biol ; 100(10): 791-804, 2022 11.

Article in English | MEDLINE | ID: mdl-36177669

13.

ß-Glucan receptors on IL-4 activated macrophages are required for hookworm larvae recognition and trapping.

Bouchery, Tiffany; Volpe, Beatrice; Doolan, Rory; Coakley, Gillian; Moyat, Mati; Esser-von Bieren, Julia; Wickramasinghe, Lakshanie C; Hibbs, Margaret L; Sotillo, Javier; Camberis, Mali; Le Gros, Graham; Khan, Nemat; Williams, David; Harris, Nicola L.

Immunol Cell Biol ; 100(4): 223-234, 2022 04.

Article in English | MEDLINE | ID: mdl-35156238

14.

Basophils promote barrier dysfunction and resolution in the atopic skin.

Pellefigues, Christophe; Naidoo, Karmella; Mehta, Palak; Schmidt, Alfonso J; Jagot, Ferdinand; Roussel, Elsa; Cait, Alissa; Yumnam, Bibek; Chappell, Sally; Meijlink, Kimberley; Camberis, Mali; Jiang, Jean X; Painter, Gavin; Filbey, Kara; Uluçkan, Özge; Gasser, Olivier; Le Gros, Graham.

J Allergy Clin Immunol ; 148(3): 799-812.e10, 2021 09.

Article in English | MEDLINE | ID: mdl-33662369

15.

Thymic stromal lymphopoietin drives the development of IL-13⁺ Th2 cells.

Ochiai, Sotaro; Jagot, Ferdinand; Kyle, Ryan L; Hyde, Evelyn; White, Ruby F; Prout, Melanie; Schmidt, Alfonso J; Yamane, Hidehiro; Lamiable, Olivier; Le Gros, Graham; Ronchese, Franca.

Proc Natl Acad Sci U S A ; 115(5): 1033-1038, 2018 01 30.

Article in English | MEDLINE | ID: mdl-29339496

16.

IL-4 Haploinsufficiency Specifically Impairs IgE Responses against Allergens in Mice.

Robinson, Marcus J; Prout, Melanie; Mearns, Helen; Kyle, Ryan; Camberis, Mali; Forbes-Blom, Elizabeth E; Paul, William E; Allen, Christopher D C; Le Gros, Graham.

J Immunol ; 198(5): 1815-1822, 2017 03 01.

Article in English | MEDLINE | ID: mdl-28115531

17.

De novo assembly of the complex genome of Nippostrongylus brasiliensis using MinION long reads.

Eccles, David; Chandler, Jodie; Camberis, Mali; Henrissat, Bernard; Koren, Sergey; Le Gros, Graham; Ewbank, Jonathan J.

BMC Biol ; 16(1): 6, 2018 01 11.

Article in English | MEDLINE | ID: mdl-29325570

18.

Macrophage-derived human resistin is induced in multiple helminth infections and promotes inflammatory monocytes and increased parasite burden.

Jang, Jessica C; Chen, Gang; Wang, Spencer H; Barnes, Mark A; Chung, Josiah I; Camberis, Mali; Le Gros, Graham; Cooper, Philip J; Steel, Cathy; Nutman, Thomas B; Lazar, Mitchell A; Nair, Meera G.

PLoS Pathog ; 11(1): e1004579, 2015 Jan.

Article in English | MEDLINE | ID: mdl-25568944

19.

Concerted activity of IgG1 antibodies and IL-4/IL-25-dependent effector cells trap helminth larvae in the tissues following vaccination with defined secreted antigens, providing sterile immunity to challenge infection.

Hewitson, James P; Filbey, Kara J; Esser-von Bieren, Julia; Camberis, Mali; Schwartz, Christian; Murray, Janice; Reynolds, Lisa A; Blair, Natalie; Robertson, Elaine; Harcus, Yvonne; Boon, Louis; Huang, Stanley Ching-Cheng; Yang, Lihua; Tu, Yizheng; Miller, Mark J; Voehringer, David; Le Gros, Graham; Harris, Nicola; Maizels, Rick M.

PLoS Pathog ; 11(3): e1004676, 2015 Mar.

Article in English | MEDLINE | ID: mdl-25816012

20.

Helminth-conditioned dendritic cells prime CD4+ T cells to IL-4 production in vivo.

Connor, Lisa M; Tang, Shiau-Choot; Camberis, Mali; Le Gros, Graham; Ronchese, Franca.

J Immunol ; 193(6): 2709-17, 2014 Sep 15.

Article in English | MEDLINE | ID: mdl-25108019

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