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1.
Acoustic Mist Ionization-Mass Spectrometry: A Comparison to Conventional High-Throughput Screening and Compound Profiling Platforms.
Anal Chem
; 92(20): 13847-13854, 2020 10 20.
Article
in English
| MEDLINE | ID: mdl-32970424
2.
The discovery of quinoline-3-carboxamides as hematopoietic prostaglandin D synthase (H-PGDS) inhibitors.
Bioorg Med Chem
; 27(8): 1456-1478, 2019 04 15.
Article
in English
| MEDLINE | ID: mdl-30858025
3.
A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response.
Nature
; 488(7411): 404-8, 2012 Aug 16.
Article
in English
| MEDLINE | ID: mdl-22842901
4.
Kruidenier et al. reply.
Nature
; 514(7520): E2, 2014 Oct 02.
Article
in English
| MEDLINE | ID: mdl-25279927
5.
Advances in high-throughput mass spectrometry in drug discovery.
EMBO Mol Med
; 15(1): e14850, 2023 01 11.
Article
in English
| MEDLINE | ID: mdl-36515561
6.
A high-throughput MALDI-TOF MS biochemical screen for small molecule inhibitors of the antigen aminopeptidase ERAP1.
SLAS Discov
; 28(1): 3-11, 2023 01.
Article
in English
| MEDLINE | ID: mdl-36414185
7.
Improving the efficiency and effectiveness of an industrial SARS-CoV-2 diagnostic facility.
Sci Rep
; 12(1): 3114, 2022 02 24.
Article
in English
| MEDLINE | ID: mdl-35210470
8.
Application of Atypical Acetyl-lysine Methyl Mimetics in the Development of Selective Inhibitors of the Bromodomain-Containing Protein 7 (BRD7)/Bromodomain-Containing Protein 9 (BRD9) Bromodomains.
J Med Chem
; 63(11): 5816-5840, 2020 06 11.
Article
in English
| MEDLINE | ID: mdl-32410449
9.
Integration of Lead Discovery Tactics and the Evolution of the Lead Discovery Toolbox.
SLAS Discov
; 23(9): 881-897, 2018 10.
Article
in English
| MEDLINE | ID: mdl-29874524
10.
A Systematic Investigation of the Best Buffers for Use in Screening by MALDI-Mass Spectrometry.
SLAS Discov
; 22(10): 1262-1269, 2017 12.
Article
in English
| MEDLINE | ID: mdl-27932699
11.
A High-Throughput Screen to Identify LRRK2 Kinase Inhibitors for the Treatment of Parkinson's Disease Using RapidFire Mass Spectrometry.
J Biomol Screen
; 21(2): 145-55, 2016 Feb.
Article
in English
| MEDLINE | ID: mdl-26403521
12.
The Evolution of MALDI-TOF Mass Spectrometry toward Ultra-High-Throughput Screening: 1536-Well Format and Beyond.
J Biomol Screen
; 21(2): 176-86, 2016 Feb.
Article
in English
| MEDLINE | ID: mdl-26428484
13.
Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 2. Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives.
J Med Chem
; 59(4): 1370-87, 2016 Feb 25.
Article
in English
| MEDLINE | ID: mdl-26771203
14.
Discovery of I-BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition.
J Med Chem
; 59(4): 1425-39, 2016 Feb 25.
Article
in English
| MEDLINE | ID: mdl-25856009
15.
Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-pyridine Carboxylate Derivatives.
J Med Chem
; 59(4): 1357-69, 2016 Feb 25.
Article
in English
| MEDLINE | ID: mdl-26771107
16.
Demonstrating enhanced throughput of RapidFire mass spectrometry through multiplexing using the JmjD2d demethylase as a model system.
J Biomol Screen
; 19(2): 278-86, 2014 Feb.
Article
in English
| MEDLINE | ID: mdl-23896685
17.
Enabling lead discovery for histone lysine demethylases by high-throughput RapidFire mass spectrometry.
J Biomol Screen
; 17(1): 39-48, 2012 Jan.
Article
in English
| MEDLINE | ID: mdl-21859681
18.
Lead discovery for microsomal prostaglandin E synthase using a combination of high-throughput fluorescent-based assays and RapidFire mass spectrometry.
J Biomol Screen
; 17(5): 641-50, 2012 Jun.
Article
in English
| MEDLINE | ID: mdl-22337655
19.
Configuration of a high-content imaging platform for hit identification and pharmacological assessment of JMJD3 demethylase enzyme inhibitors.
J Biomol Screen
; 17(1): 108-20, 2012 Jan.
Article
in English
| MEDLINE | ID: mdl-22223398
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