Search | Virtual Health Library

1.

Snapshot of the cannabinoid receptor 1-arrestin complex unravels the biased signaling mechanism.

Liao, Yu-Ying; Zhang, Huibing; Shen, Qingya; Cai, Chenxi; Ding, Yu; Shen, Dan-Dan; Guo, Jia; Qin, Jiao; Dong, Yingjun; Zhang, Yan; Li, Xiao-Ming.

Cell ; 186(26): 5784-5797.e17, 2023 12 21.

Article in English | MEDLINE | ID: mdl-38101408

2.

Chromosome-level organization of the regulatory genome in the Drosophila nervous system.

Mohana, Giriram; Dorier, Julien; Li, Xiao; Mouginot, Marion; Smith, Rebecca C; Malek, Héléna; Leleu, Marion; Rodriguez, Daniel; Khadka, Jenisha; Rosa, Patrycja; Cousin, Pascal; Iseli, Christian; Restrepo, Simon; Guex, Nicolas; McCabe, Brian D; Jankowski, Aleksander; Levine, Michael S; Gambetta, Maria Cristina.

Cell ; 186(18): 3826-3844.e26, 2023 08 31.

Article in English | MEDLINE | ID: mdl-37536338

3.

Structural and signaling mechanisms of TAAR1 enabled preferential agonist design.

Shang, Pan; Rong, Naikang; Jiang, Jing-Jing; Cheng, Jie; Zhang, Ming-Hui; Kang, Dongwei; Qi, Lei; Guo, Lulu; Yang, Gong-Ming; Liu, Qun; Zhou, Zhenzhen; Li, Xiao-Bing; Zhu, Kong-Kai; Meng, Qing-Biao; Han, Xiang; Yan, Wenqi; Kong, Yalei; Yang, Lejin; Wang, Xiaohui; Lei, Dapeng; Feng, Xin; Liu, Xinyong; Yu, Xiao; Wang, Yue; Li, Qian; Shao, Zhen-Hua; Yang, Fan; Sun, Jin-Peng.

Cell ; 186(24): 5347-5362.e24, 2023 11 22.

Article in English | MEDLINE | ID: mdl-37963465

4.

Trimodal single-cell profiling reveals a novel pediatric CD8αα⁺ T cell subset and broad age-related molecular reprogramming across the T cell compartment.

Thomson, Zachary; He, Ziyuan; Swanson, Elliott; Henderson, Katherine; Phalen, Cole; Zaim, Samir Rachid; Pebworth, Mark-Phillip; Okada, Lauren Y; Heubeck, Alexander T; Roll, Charles R; Hernandez, Veronica; Weiss, Morgan; Genge, Palak C; Reading, Julian; Giles, Josephine R; Manne, Sasikanth; Dougherty, Jeanette; Jasen, C J; Greenplate, Allison R; Becker, Lynne A; Graybuck, Lucas T; Vasaikar, Suhas V; Szeto, Gregory L; Savage, Adam K; Speake, Cate; Buckner, Jane H; Li, Xiao-Jun; Bumol, Thomas F; Wherry, E John; Torgerson, Troy R; Vella, Laura A; Henrickson, Sarah E; Skene, Peter J; Gustafson, Claire E.

Nat Immunol ; 24(11): 1947-1959, 2023 Nov.

Article in English | MEDLINE | ID: mdl-37845489

5.

A Quantitative Proteome Map of the Human Body.

Jiang, Lihua; Wang, Meng; Lin, Shin; Jian, Ruiqi; Li, Xiao; Chan, Joanne; Dong, Guanlan; Fang, Huaying; Robinson, Aaron E; Snyder, Michael P.

Cell ; 183(1): 269-283.e19, 2020 10 01.

Article in English | MEDLINE | ID: mdl-32916130

6.

A Thermostable mRNA Vaccine against COVID-19.

Zhang, Na-Na; Li, Xiao-Feng; Deng, Yong-Qiang; Zhao, Hui; Huang, Yi-Jiao; Yang, Guan; Huang, Wei-Jin; Gao, Peng; Zhou, Chao; Zhang, Rong-Rong; Guo, Yan; Sun, Shi-Hui; Fan, Hang; Zu, Shu-Long; Chen, Qi; He, Qi; Cao, Tian-Shu; Huang, Xing-Yao; Qiu, Hong-Ying; Nie, Jian-Hui; Jiang, Yuhang; Yan, Hua-Yuan; Ye, Qing; Zhong, Xia; Xue, Xia-Lin; Zha, Zhen-Yu; Zhou, Dongsheng; Yang, Xiao; Wang, You-Chun; Ying, Bo; Qin, Cheng-Feng.

Cell ; 182(5): 1271-1283.e16, 2020 09 03.

Article in English | MEDLINE | ID: mdl-32795413

7.

Astrocytic trans-Differentiation Completes a Multicellular Paracrine Feedback Loop Required for Medulloblastoma Tumor Growth.

Yao, Maojin; Ventura, P Britten; Jiang, Ying; Rodriguez, Fausto J; Wang, Lixin; Perry, Justin S A; Yang, Yibo; Wahl, Kelsey; Crittenden, Rowena B; Bennett, Mariko L; Qi, Lin; Gong, Cong-Cong; Li, Xiao-Nan; Barres, Ben A; Bender, Timothy P; Ravichandran, Kodi S; Janes, Kevin A; Eberhart, Charles G; Zong, Hui.

Cell ; 180(3): 502-520.e19, 2020 02 06.

Article in English | MEDLINE | ID: mdl-31983537

8.

Gene-Environment Interaction in the Era of Precision Medicine.

Li, Jingjing; Li, Xiao; Zhang, Sai; Snyder, Michael.

Cell ; 177(1): 38-44, 2019 03 21.

Article in English | MEDLINE | ID: mdl-30901546

9.

Human Diseases from Gain-of-Function Mutations in Disordered Protein Regions.

Li, Xiao-Han; Babu, M Madan.

Cell ; 175(1): 40-42, 2018 09 20.

Article in English | MEDLINE | ID: mdl-30241614

10.

A Huntingtin Knockin Pig Model Recapitulates Features of Selective Neurodegeneration in Huntington's Disease.

Yan, Sen; Tu, Zhuchi; Liu, Zhaoming; Fan, Nana; Yang, Huiming; Yang, Su; Yang, Weili; Zhao, Yu; Ouyang, Zhen; Lai, Chengdan; Yang, Huaqiang; Li, Li; Liu, Qishuai; Shi, Hui; Xu, Guangqing; Zhao, Heng; Wei, Hongjiang; Pei, Zhong; Li, Shihua; Lai, Liangxue; Li, Xiao-Jiang.

Cell ; 173(4): 989-1002.e13, 2018 05 03.

Article in English | MEDLINE | ID: mdl-29606351

11.

Lymphatic endothelial transcription factor Tbx1 promotes an immunosuppressive microenvironment to facilitate post-myocardial infarction repair.

Wang, Wenfeng; Li, Xiao; Ding, Xiaoning; Xiong, Shanshan; Hu, Zhenlei; Lu, Xuan; Zhang, Kan; Zhang, Heng; Hu, Qianwen; Lai, Kaa Seng; Chen, Zhongxiang; Yang, Junjie; Song, Hejie; Wang, Ye; Wei, Lu; Xia, Zeyang; Zhou, Bin; He, Yulong; Pu, Jun; Liu, Xiao; Ke, Rongqin; Wu, Tao; Huang, Chuanxin; Baldini, Antonio; Zhang, Min; Zhang, Zhen.

Immunity ; 56(10): 2342-2357.e10, 2023 Oct 10.

Article in English | MEDLINE | ID: mdl-37625409

12.

Anti-apoptotic MCL-1 promotes long-chain fatty acid oxidation through interaction with ACSL1.

Wright, Tristen; Turnis, Meghan E; Grace, Christy R; Li, Xiao; Brakefield, Lauren A; Wang, Yong-Dong; Xu, Haiyan; Kaminska, Ewa; Climer, Leslie K; Mukiza, Tresor O; Chang, Chi-Lun; Moldoveanu, Tudor; Opferman, Joseph T.

Mol Cell ; 84(7): 1338-1353.e8, 2024 Apr 04.

Article in English | MEDLINE | ID: mdl-38503284

13.

Author Correction: Trimodal single-cell profiling reveals a novel pediatric CD8αα⁺ T cell subset and broad age-related molecular reprogramming across the T cell compartment.

Thomson, Zachary; He, Ziyuan; Swanson, Elliott; Henderson, Katherine; Phalen, Cole; Zaim, Samir Rachid; Pebworth, Mark-Phillip; Okada, Lauren Y; Heubeck, Alexander T; Roll, Charles R; Hernandez, Veronica; Weiss, Morgan; Genge, Palak C; Reading, Julian; Giles, Josephine R; Manne, Sasikanth; Dougherty, Jeanette; Jasen, C J; Greenplate, Allison R; Becker, Lynne A; Graybuck, Lucas T; Vasaikar, Suhas V; Szeto, Gregory L; Savage, Adam K; Speake, Cate; Buckner, Jane H; Li, Xiao-Jun; Bumol, Thomas F; Wherry, E John; Torgerson, Troy R; Vella, Laura A; Henrickson, Sarah E; Skene, Peter J; Gustafson, Claire E.

Nat Immunol ; 25(3): 577, 2024 Mar.

Article in English | MEDLINE | ID: mdl-38267693

14.

GAGA-associated factor fosters loop formation in the Drosophila genome.

Li, Xiao; Tang, Xiaona; Bing, Xinyang; Catalano, Christopher; Li, Taibo; Dolsten, Gabriel; Wu, Carl; Levine, Michael.

Mol Cell ; 83(9): 1519-1526.e4, 2023 05 04.

Article in English | MEDLINE | ID: mdl-37003261

15.

IL-17-receptor-associated adaptor Act1 directly stabilizes mRNAs to mediate IL-17 inflammatory signaling.

Herjan, Tomasz; Hong, Lingzi; Bubenik, Jodi; Bulek, Katarzyna; Qian, Wen; Liu, Caini; Li, Xiao; Chen, Xing; Yang, Hui; Ouyang, Suidong; Zhou, Hao; Zhao, Junjie; Vasu, Kommireddy; Cockman, Eric; Aronica, Mark; Asosingh, Kewal; Licatalosi, Donny D; Qin, Jun; Fox, Paul L; Hamilton, Thomas A; Driscoll, Donna; Li, Xiaoxia.

Nat Immunol ; 19(4): 354-365, 2018 04.

Article in English | MEDLINE | ID: mdl-29563620

16.

Distinct human Langerhans cell subsets orchestrate reciprocal functions and require different developmental regulation.

Liu, Xiaochun; Zhu, Ronghui; Luo, Yang; Wang, Shangshang; Zhao, Yi; Qiu, Zhuoqiong; Zhang, Yu; Liu, Xiao; Yao, Xu; Li, Xiao; Li, Wei.

Immunity ; 54(10): 2305-2320.e11, 2021 10 12.

Article in English | MEDLINE | ID: mdl-34508661

17.

SPARCLE, a p53-induced lncRNA, controls apoptosis after genotoxic stress by promoting PARP-1 cleavage.

Meza-Sosa, Karla F; Miao, Rui; Navarro, Francisco; Zhang, Zhibin; Zhang, Ying; Hu, Jun Jacob; Hartford, Corrine Corrina R; Li, Xiao Ling; Pedraza-Alva, Gustavo; Pérez-Martínez, Leonor; Lal, Ashish; Wu, Hao; Lieberman, Judy.

Mol Cell ; 82(4): 785-802.e10, 2022 02 17.

Article in English | MEDLINE | ID: mdl-35104452

18.

Mechanisms of neurotransmitter transport and drug inhibition in human VMAT2.

Pidathala, Shabareesh; Liao, Shuyun; Dai, Yaxin; Li, Xiao; Long, Changkun; Chang, Chi-Lun; Zhang, Zhe; Lee, Chia-Hsueh.

Nature ; 623(7989): 1086-1092, 2023 Nov.

Article in English | MEDLINE | ID: mdl-37914936

19.

Dynamics in Fip1 regulate eukaryotic mRNA 3' end processing.

Kumar, Ananthanarayanan; Yu, Conny W H; Rodríguez-Molina, Juan B; Li, Xiao-Han; Freund, Stefan M V; Passmore, Lori A.

Genes Dev ; 35(21-22): 1510-1526, 2021 11 01.

Article in English | MEDLINE | ID: mdl-34593603

20.

The p53-induced RNA-binding protein ZMAT3 is a splicing regulator that inhibits the splicing of oncogenic CD44 variants in colorectal carcinoma.

Muys, Bruna R; Anastasakis, Dimitrios G; Claypool, Duncan; Pongor, Lörinc; Li, Xiao Ling; Grammatikakis, Ioannis; Liu, Minxue; Wang, Xiantao; Prasanth, Kannanganattu V; Aladjem, Mirit I; Lal, Ashish; Hafner, Markus.

Genes Dev ; 35(1-2): 102-116, 2021 01 01.

Article in English | MEDLINE | ID: mdl-33334821

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