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1.
Resting-state fMRI reveals longitudinal alterations in brain network connectivity in the zQ175DN mouse model of Huntington's disease.
Neurobiol Dis
; 181: 106095, 2023 06 01.
Article
in English
| MEDLINE | ID: mdl-36963694
2.
Longitudinal preclinical evaluation of the novel radioligand [11C]CHDI-626 for PET imaging of mutant huntingtin aggregates in Huntington's disease.
Eur J Nucl Med Mol Imaging
; 49(4): 1166-1175, 2022 03.
Article
in English
| MEDLINE | ID: mdl-34651228
3.
Biodistribution and dosimetry in human healthy volunteers of the PET radioligands [11C]CHDI-00485180-R and [11C]CHDI-00485626, designed for quantification of cerebral aggregated mutant huntingtin.
Eur J Nucl Med Mol Imaging
; 50(1): 48-60, 2022 Dec.
Article
in English
| MEDLINE | ID: mdl-36001116
4.
[The Role of Nrf2 Pathway Activation in Hippocampal Neuron Injury of Neonatal Rats with Bilirubin Encephalopathy].
Sichuan Da Xue Xue Bao Yi Xue Ban
; 52(6): 960-965, 2021 Nov.
Article
in Zh
| MEDLINE | ID: mdl-34841762
5.
The development of a structurally distinct series of BACE1 inhibitors via the (Z)-fluoro-olefin amide bioisosteric replacement.
Bioorg Med Chem Lett
; 30(14): 127240, 2020 07 15.
Article
in English
| MEDLINE | ID: mdl-32527542
6.
Antidiabetic effects of glucokinase regulatory protein small-molecule disruptors.
Nature
; 504(7480): 437-40, 2013 Dec 19.
Article
in English
| MEDLINE | ID: mdl-24226772
7.
An Onboard Vision-Based System for Autonomous Landing of a Low-Cost Quadrotor on a Novel Landing Pad.
Sensors (Basel)
; 19(21)2019 Oct 29.
Article
in English
| MEDLINE | ID: mdl-31671894
8.
Primary Culture of Rat Aortic Vascular Smooth Muscle Cells: A New Method.
Med Sci Monit
; 23: 4014-4020, 2017 Aug 19.
Article
in English
| MEDLINE | ID: mdl-28822209
9.
Polyphenols and Polypeptides in Chinese Rice Wine Inhibit Homocysteine-induced Proliferation and Migration of Vascular Smooth Muscle Cells.
J Cardiovasc Pharmacol
; 67(6): 482-90, 2016 Jun.
Article
in English
| MEDLINE | ID: mdl-26836482
10.
Purinylpyridinylamino-based DFG-in/αC-helix-out B-Raf inhibitors: Applying mutant versus wild-type B-Raf selectivity indices for compound profiling.
Bioorg Med Chem
; 24(10): 2215-34, 2016 05 15.
Article
in English
| MEDLINE | ID: mdl-27085672
11.
In Vivo Cerebral Imaging of Mutant Huntingtin Aggregates Using 11C-CHDI-180R PET in a Nonhuman Primate Model of Huntington Disease.
J Nucl Med
; 64(10): 1581-1587, 2023 10.
Article
in English
| MEDLINE | ID: mdl-37591545
12.
Longitudinal investigation of changes in resting-state co-activation patterns and their predictive ability in the zQ175 DN mouse model of Huntington's disease.
Sci Rep
; 13(1): 10194, 2023 06 23.
Article
in English
| MEDLINE | ID: mdl-37353500
13.
Design and Evaluation of [18F]CHDI-650 as a Positron Emission Tomography Ligand to Image Mutant Huntingtin Aggregates.
J Med Chem
; 66(1): 641-656, 2023 01 12.
Article
in English
| MEDLINE | ID: mdl-36548390
14.
Identification and Optimization of RNA-Splicing Modulators as Huntingtin Protein-Lowering Agents for the Treatment of Huntington's Disease.
J Med Chem
; 66(18): 13205-13246, 2023 Sep 28.
Article
in English
| MEDLINE | ID: mdl-37712656
15.
Synthesis and structure-activity relationships of dual PI3K/mTOR inhibitors based on a 4-amino-6-methyl-1,3,5-triazine sulfonamide scaffold.
Bioorg Med Chem Lett
; 22(17): 5714-20, 2012 Sep 01.
Article
in English
| MEDLINE | ID: mdl-22832322
16.
Rosuvastatin may modulate insulin signaling and inhibit atherogenesis beyond its plasma cholesterol-lowering effect in insulin-resistant mice.
Cardiovasc Drugs Ther
; 26(5): 375-82, 2012 Oct.
Article
in English
| MEDLINE | ID: mdl-22918601
17.
Predictive value of using plasma long non-coding RNAs ANRIL and HOXA11-AS for in-stent restenosis.
Exp Ther Med
; 23(2): 115, 2022 Feb.
Article
in English
| MEDLINE | ID: mdl-34970338
18.
Validation, kinetic modeling, and test-retest reproducibility of [18F]SynVesT-1 for PET imaging of synaptic vesicle glycoprotein 2A in mice.
J Cereb Blood Flow Metab
; 42(10): 1867-1878, 2022 10.
Article
in English
| MEDLINE | ID: mdl-35570828
19.
Synaptic Vesicle Glycoprotein 2A Is Affected in the Central Nervous System of Mice with Huntington Disease and in the Brain of a Human with Huntington Disease Postmortem.
J Nucl Med
; 63(6): 942-947, 2022 06.
Article
in English
| MEDLINE | ID: mdl-34531262
20.
Development of a ligand for in vivo imaging of mutant huntingtin in Huntington's disease.
Sci Transl Med
; 14(630): eabm3682, 2022 02 02.
Article
in English
| MEDLINE | ID: mdl-35108063