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Nat Prod Commun ; 11(2): 173-6, 2016 Feb.
Article in English | MEDLINE | ID: mdl-27032193

ABSTRACT

Nineteen compounds, including seven triterpenoids (1-7), five steroids (8-12), four cyclohexenone derivatives (13-16), two benzenoid glycosides (17 and 18) and one lignan (19), were isolated and separated from the leaves of Pandanus utilis through bioactivity-guided fractionation. Among them, one new lanosterol- type triterpenoid was found and named as (24R)-24-methyl-5a-4-demethyllanosta-9(11),25-dien-3ß-ol (1). The structures of the isolates were determined by mass and spectroscopic analyses, and the compounds were subjected to anti-inflammatory, anti-oxidative and cytotoxic assays.


Subject(s)
Pandanaceae/chemistry , Plant Leaves/chemistry , Anti-Inflammatory Agents/chemistry , Anti-Inflammatory Agents/pharmacology , Antineoplastic Agents, Phytogenic/chemistry , Antineoplastic Agents, Phytogenic/pharmacology , Antioxidants/chemistry , Antioxidants/pharmacology , Cell Line, Tumor , Glycosides/chemistry , Humans , Lignans/chemistry , Models, Molecular , Molecular Structure , Steroids/chemistry , Triterpenes/chemistry
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