Search details
1.
Synthesis of 12ß-methyl-18-nor-avicholic acid analogues as potential TGR5 agonists.
Org Biomol Chem
; 20(17): 3511-3527, 2022 05 04.
Article
in English
| MEDLINE | ID: mdl-35230376
2.
C5-Iminosugar modification of casein kinase 1δ lead 3-(4-fluorophenyl)-5-isopropyl-4-(pyridin-4-yl)isoxazole promotes enhanced inhibitor affinity and selectivity.
Arch Pharm (Weinheim)
; 355(5): e2100497, 2022 May.
Article
in English
| MEDLINE | ID: mdl-35174898
3.
Synthesis of Novel C/D Ring Modified Bile Acids.
Molecules
; 27(7)2022 Apr 06.
Article
in English
| MEDLINE | ID: mdl-35408759
4.
Design, Synthesis and Biological Evaluation of Isoxazole-Based CK1 Inhibitors Modified with Chiral Pyrrolidine Scaffolds.
Molecules
; 24(5)2019 Mar 01.
Article
in English
| MEDLINE | ID: mdl-30832206
5.
Optimized 4,5-Diarylimidazoles as Potent/Selective Inhibitors of Protein Kinase CK1δ and Their Structural Relation to p38α MAPK.
Molecules
; 22(4)2017 Mar 24.
Article
in English
| MEDLINE | ID: mdl-28338621
6.
Tight binding enantiomers of pre-clinical drug candidates.
Bioorg Med Chem
; 23(17): 5326-33, 2015 Sep 01.
Article
in English
| MEDLINE | ID: mdl-26260335
7.
The discovery of 12ß-methyl-17-epi-18-nor-bile acids as potent and selective TGR5 agonists.
Eur J Med Chem
; 250: 115143, 2023 Mar 15.
Article
in English
| MEDLINE | ID: mdl-36841086
8.
(9H-Fluoren-9-yl)methyl N-{(2R,3R,4S)-4-hy-droxy-2-[(2S,5R)-2-isopropyl-5-methyl-cyclo-hex-yloxy]-5-oxooxolan-3-yl}carbamate propan-2-ol 0.334-solvate.
Acta Crystallogr Sect E Struct Rep Online
; 68(Pt 2): o403-4, 2012 Feb 01.
Article
in English
| MEDLINE | ID: mdl-22347023
9.
Synthesis and Characterization of Transition-State Analogue Inhibitors against Human DNA Methyltransferase 1.
J Med Chem
; 65(7): 5462-5494, 2022 04 14.
Article
in English
| MEDLINE | ID: mdl-35324190
10.
3α,7-Dihydroxy-14(13â12)abeo-5ß,12α(H),13ß(H)-cholan-24-oic Acids Display Neuroprotective Properties in Common Forms of Parkinson's Disease.
Biomolecules
; 13(1)2022 12 30.
Article
in English
| MEDLINE | ID: mdl-36671460
11.
Alkyl 4-chlorobenzoyloxycarbamates as highly effective nitrogen source reagents for the base-free, intermolecular aminohydroxylation reaction.
J Org Chem
; 76(2): 358-72, 2011 Jan 21.
Article
in English
| MEDLINE | ID: mdl-21190319
12.
Discovery of AL-GDa62 as a Potential Synthetic Lethal Lead for the Treatment of Gastric Cancer.
J Med Chem
; 64(24): 18114-18142, 2021 12 23.
Article
in English
| MEDLINE | ID: mdl-34878770
13.
Synthesis of 12ß-Methyl-18-nor-bile Acids.
ACS Omega
; 6(38): 25019-25039, 2021 Sep 28.
Article
in English
| MEDLINE | ID: mdl-34604682
14.
(1R,3R,4S)-1-benzyl-3-(tert-butyldimethylsilyloxy)-4-(hydroxymethyl)pyrrolidine-borane: novel B-H...H-O hydrogen bonding.
Acta Crystallogr C
; 66(Pt 8): o418-20, 2010 Aug.
Article
in English
| MEDLINE | ID: mdl-20679720
15.
(2S,3R,4S,5R)-Diethyl 2-(10,10-dimethyl-3,3-dioxo-3lambda(6)-thia-4-azatricyclo[5.2.1.0(1,5)]decan-4-ylcarbonyl)-5-phenylpyrrolidine-3,4-dicarboxylate: a novel isomorphous-by-addition compound.
Acta Crystallogr C
; 65(Pt 1): o15-8, 2009 Jan.
Article
in English
| MEDLINE | ID: mdl-19129602
16.
'Segmented' crystals solved using synchrotron radiation: (2S,3R,4S,5R)-4-(10,10-dimethyl-3,3-dioxo-3lambda6-thia-4-azatricyclo[5.2.1.0(1,5)]decan-4-ylcarbonyl)-2,6-diphenylperhydropyrrolo[3,4-c]pyrrole-1,3-dione.
Acta Crystallogr C
; 65(Pt 7): o331-4, 2009 Jul.
Article
in English
| MEDLINE | ID: mdl-19578266
17.
(3R,6S,7aS)-3-Phenyl-6-(phenyl-sulfan-yl)perhydro-pyrrolo[1,2-c]oxazol-5-one.
Acta Crystallogr Sect E Struct Rep Online
; 65(Pt 5): o943, 2009 Apr 02.
Article
in English
| MEDLINE | ID: mdl-21583987
18.
A high-throughput screen to identify novel synthetic lethal compounds for the treatment of E-cadherin-deficient cells.
Sci Rep
; 9(1): 12511, 2019 08 29.
Article
in English
| MEDLINE | ID: mdl-31467357
19.
A novel class of potent nonglycosidic and nonpeptidic pan-selectin inhibitors.
J Med Chem
; 49(20): 5988-99, 2006 Oct 05.
Article
in English
| MEDLINE | ID: mdl-17004713
20.
Alkali metal counterion control of enolate protonation stereoselectivity.
Org Lett
; 8(13): 2735-7, 2006 Jun 22.
Article
in English
| MEDLINE | ID: mdl-16774244