Search details
1.
Inhibition of CREB Binding and Function with a Dual-Targeting Ligand.
Biochemistry
; 63(1): 1-8, 2024 Jan 02.
Article
in English
| MEDLINE | ID: mdl-38086054
2.
A Lipopeptidomimetic of Transcriptional Activation Domains Selectively Disrupts the Coactivator Med25 Protein-Protein Interactions.
Angew Chem Int Ed Engl
; 63(21): e202400781, 2024 May 21.
Article
in English
| MEDLINE | ID: mdl-38527936
3.
Garcinolic Acid Distinguishes Between GACKIX Domains and Modulates Interaction Networks.
Chembiochem
; 24(21): e202300439, 2023 11 02.
Article
in English
| MEDLINE | ID: mdl-37525583
4.
Allostery in the dynamic coactivator domain KIX occurs through minor conformational micro-states.
PLoS Comput Biol
; 18(4): e1009977, 2022 04.
Article
in English
| MEDLINE | ID: mdl-35452454
5.
Unexpected specificity within dynamic transcriptional protein-protein complexes.
Proc Natl Acad Sci U S A
; 117(44): 27346-27353, 2020 11 03.
Article
in English
| MEDLINE | ID: mdl-33077600
6.
Copper-Mediated Radiocyanation of Unprotected Amino Acids and Peptides.
J Am Chem Soc
; 144(16): 7422-7429, 2022 04 27.
Article
in English
| MEDLINE | ID: mdl-35437016
7.
A Dual-Site Inhibitor of CBP/p300 KIX is a Selective and Effective Modulator of Myb.
J Am Chem Soc
; 143(37): 15056-15062, 2021 09 22.
Article
in English
| MEDLINE | ID: mdl-34491719
8.
Norstictic Acid Is a Selective Allosteric Transcriptional Regulator.
J Am Chem Soc
; 143(25): 9297-9302, 2021 06 30.
Article
in English
| MEDLINE | ID: mdl-34137598
9.
Conservation of coactivator engagement mechanism enables small-molecule allosteric modulators.
Proc Natl Acad Sci U S A
; 115(36): 8960-8965, 2018 09 04.
Article
in English
| MEDLINE | ID: mdl-30127017
10.
X-linked inhibitor of apoptosis protein (XIAP) is a client of heat shock protein 70 (Hsp70) and a biomarker of its inhibition.
J Biol Chem
; 293(7): 2370-2380, 2018 02 16.
Article
in English
| MEDLINE | ID: mdl-29255093
11.
Covalent Chemical Cochaperones of the p300/CBP GACKIX Domain.
Chembiochem
; 19(18): 1907-1912, 2018 09 17.
Article
in English
| MEDLINE | ID: mdl-29939485
12.
From Fuzzy to Function: The New Frontier of Protein-Protein Interactions.
Acc Chem Res
; 50(3): 584-589, 2017 03 21.
Article
in English
| MEDLINE | ID: mdl-28945413
13.
Protein cross-linking capillary electrophoresis at increased throughput for a range of protein-protein interactions.
Analyst
; 143(8): 1805-1812, 2018 Apr 16.
Article
in English
| MEDLINE | ID: mdl-29565056
14.
BET bromodomain ligands: Probing the WPF shelf to improve BRD4 bromodomain affinity and metabolic stability.
Bioorg Med Chem
; 26(11): 2937-2957, 2018 07 15.
Article
in English
| MEDLINE | ID: mdl-29776834
15.
A Bifunctional Amino Acid Enables Both Covalent Chemical Capture and Isolation of in Vivo Protein-Protein Interactions.
Chembiochem
; 18(2): 181-184, 2017 Jan 17.
Article
in English
| MEDLINE | ID: mdl-27966261
16.
Dissecting allosteric effects of activator-coactivator complexes using a covalent small molecule ligand.
Proc Natl Acad Sci U S A
; 111(33): 12061-6, 2014 Aug 19.
Article
in English
| MEDLINE | ID: mdl-25049401
17.
Prepaying the entropic cost for allosteric regulation in KIX.
Proc Natl Acad Sci U S A
; 111(33): 12067-72, 2014 Aug 19.
Article
in English
| MEDLINE | ID: mdl-25002472
18.
Discovery of Enzymatic Targets of Transcriptional Activators via in Vivo Covalent Chemical Capture.
J Am Chem Soc
; 138(38): 12629-35, 2016 09 28.
Article
in English
| MEDLINE | ID: mdl-27611834
19.
A Synthetic Loop Replacement Peptide That Blocks Canonical NF-κB Signaling.
Angew Chem Int Ed Engl
; 55(48): 14997-15001, 2016 11 21.
Article
in English
| MEDLINE | ID: mdl-27791341
20.
Direct measurements of oscillatory glycolysis in pancreatic islet ß-cells using novel fluorescence resonance energy transfer (FRET) biosensors for pyruvate kinase M2 activity.
J Biol Chem
; 288(46): 33312-22, 2013 11 15.
Article
in English
| MEDLINE | ID: mdl-24100037