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Int J Mol Sci ; 20(16)2019 Aug 08.
Article in English | MEDLINE | ID: mdl-31398812

ABSTRACT

Recent scientific research has shown the use of chlorin, phthalocyanines, and porphyrins derivatives as photosensitizers in photodynamic therapy in the treatment of various pathologies, including some of the major skin diseases. Thus, the main goal of this critical review is to catalog the papers that used these photosensitizers in the treatment of acne vulgaris, psoriasis, papillomavirus infections, cutaneous leishmaniasis, and skin rejuvenation, and to explore the photodynamic therapy mechanisms against these conditions alongside their clinical benefits.


Subject(s)
Indoles/therapeutic use , Photochemotherapy , Photosensitizing Agents/therapeutic use , Porphyrins/therapeutic use , Skin Diseases/drug therapy , Skin/drug effects , Animals , Humans , Indoles/pharmacology , Isoindoles , Photochemotherapy/methods , Photosensitizing Agents/pharmacology , Porphyrins/pharmacology , Skin/pathology , Skin Diseases/diagnosis , Skin Diseases/etiology , Treatment Outcome
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