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Infect Control Hosp Epidemiol ; 29(2): 180-2, 2008 Feb.
Article in English | MEDLINE | ID: mdl-18179375

ABSTRACT

A retrospective analysis of 13,946 Staphylococcus aureus isolates revealed a stable incidence of isolates that were resistant to both clindamycin and erythromycin, but a significantly increasing incidence of isolates that were susceptible to clindamycin and resistant to erythromycin during 1991-1995, 1996-2000, and 2001-2005. The use of macrolides and clindamycin also increased during 1996-2005. The incidence of S. aureus isolates with inducible clindamycin resistance increased steadily and significantly during the period from August 2004 through December 2005.


Subject(s)
Clindamycin/pharmacology , Drug Resistance, Multiple, Bacterial , Macrolides/pharmacology , Staphylococcus aureus/drug effects , Anti-Bacterial Agents/pharmacology , Humans , Retrospective Studies , Staphylococcal Infections/microbiology , Staphylococcus aureus/classification , Staphylococcus aureus/isolation & purification
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