Search | Virtual Health Library

1.

Identifying and mathematically modeling the time-course of extracellular metabolic markers associated with resistance to ceftolozane/tazobactam in Pseudomonas aeruginosa.

Tait, Jessica R; Anderson, Dovile; Nation, Roger L; Creek, Darren J; Landersdorfer, Cornelia B.

Antimicrob Agents Chemother ; 68(4): e0108123, 2024 Apr 03.

Article in English | MEDLINE | ID: mdl-38376189

2.

Evaluation of Empirical Dosing Regimens for Meropenem in Intensive Care Unit Patients Using Population Pharmacokinetic Modeling and Target Attainment Analysis.

An, Guohua; Creech, C Buddy; Wu, Nan; Nation, Roger L; Gu, Kenan; Nalbant, Demet; Jimenez-Truque, Natalia; Fissell, William; Rolsma, Stephanie; Patel, Pratish C; Watanabe, Amy; Fishbane, Nicholas; Kirkpatrick, Carl M J; Landersdorfer, Cornelia B; Winokur, Patricia.

Antimicrob Agents Chemother ; 67(1): e0131222, 2023 01 24.

Article in English | MEDLINE | ID: mdl-36622154

3.

Ceftolozane-Tazobactam against Pseudomonas aeruginosa Cystic Fibrosis Clinical Isolates in the Hollow-Fiber Infection Model: Challenges Imposed by Hypermutability and Heteroresistance.

Tait, Jessica R; Harper, Marina; Cortés-Lara, Sara; Rogers, Kate E; López-Causapé, Carla; Smallman, Thomas R; Lang, Yinzhi; Lee, Wee Leng; Zhou, Jieqiang; Bulitta, Jürgen B; Nation, Roger L; Boyce, John D; Oliver, Antonio; Landersdorfer, Cornelia B.

Antimicrob Agents Chemother ; 67(8): e0041423, 2023 08 17.

Article in English | MEDLINE | ID: mdl-37428034

4.

Population pharmacokinetics and target attainment analyses to identify a rational empirical dosing strategy for cefepime in critically ill patients.

An, Guohua; Creech, C Buddy; Wu, Nan; Nation, Roger L; Gu, Kenan; Nalbant, Demet; Jimenez-Truque, Natalia; Fissell, William; Patel, Pratish C; Fishbane, Nicholas; Watanabe, Amy; Rolsma, Stephanie; Kirkpatrick, Carl M J; Landersdorfer, Cornelia B; Winokur, Patricia.

J Antimicrob Chemother ; 78(6): 1460-1470, 2023 06 01.

Article in English | MEDLINE | ID: mdl-37071586

5.

Penetration of Vancomycin into Noninfected Bone in Patients Undergoing Total Joint Arthroplasty Evaluated by a Minimal Physiologically Based Population Pharmacokinetic Modeling Approach.

Landersdorfer, Cornelia B; Lee, Wee Leng; Nation, Roger L; Kong, David C M; Buising, Kirsty; Peel, Trisha N; Choong, Peter F M.

Mol Pharm ; 20(3): 1509-1518, 2023 03 06.

Article in English | MEDLINE | ID: mdl-36512679

6.

Simulated Intravenous versus Inhaled Tobramycin with or without Intravenous Ceftazidime Evaluated against Hypermutable Pseudomonas aeruginosa via a Dynamic Biofilm Model and Mechanism-Based Modeling.

Bilal, Hajira; Tait, Jessica R; Lang, Yinzhi; Zhou, Jieqiang; Bergen, Phillip J; Peleg, Anton Y; Bulitta, Jürgen B; Oliver, Antonio; Nation, Roger L; Landersdorfer, Cornelia B.

Antimicrob Agents Chemother ; 66(3): e0220321, 2022 03 15.

Article in English | MEDLINE | ID: mdl-35041509

7.

A Systems-Based Analysis of Mono- and Combination Therapy for Carbapenem-Resistant Klebsiella pneumoniae Bloodstream Infections.

Luterbach, Courtney L; Qiu, Hongqiang; Hanafin, Patrick O; Sharma, Rajnikant; Piscitelli, Joseph; Lin, Feng-Chang; Ilomaki, Jenni; Cober, Eric; Salata, Robert A; Kalayjian, Robert C; Watkins, Richard R; Doi, Yohei; Kaye, Keith S; Nation, Roger L; Bonomo, Robert A; Landersdorfer, Cornelia B; van Duin, David; Rao, Gauri G.

Antimicrob Agents Chemother ; 66(10): e0059122, 2022 10 18.

Article in English | MEDLINE | ID: mdl-36125299

8.

Penicillin G concentrations required for prophylaxis against Group A Streptococcus infection evaluated using a hollow fibre model and mathematical modelling.

Tait, Jessica R; Barnett, Timothy C; Rogers, Kate E; Lee, Wee Leng; Page-Sharp, Madhu; Manning, Laurens; Boyd, Ben J; Carapetis, Jonathan R; Nation, Roger L; Landersdorfer, Cornelia B.

J Antimicrob Chemother ; 77(7): 1923-1930, 2022 06 29.

Article in English | MEDLINE | ID: mdl-35470370

9.

Population Pharmacokinetics and Outcomes of Critically Ill Pediatric Patients Treated with Intravenous Colistin at Higher Than Recommended Doses.

Antachopoulos, Charalampos; Geladari, Anastasia; Landersdorfer, Cornelia B; Volakli, Eleni; Ilia, Stavroula; Gikas, Evangelos; Gika, Helen; Sdougka, Maria; Nation, Roger L; Roilides, Emmanuel.

Antimicrob Agents Chemother ; 65(6)2021 05 18.

Article in English | MEDLINE | ID: mdl-33782000

10.

Clinically Relevant Epithelial Lining Fluid Concentrations of Meropenem with Ciprofloxacin Provide Synergistic Killing and Resistance Suppression of Hypermutable Pseudomonas aeruginosa in a Dynamic Biofilm Model.

Bilal, Hajira; Bergen, Phillip J; Tait, Jessica R; Wallis, Steven C; Peleg, Anton Y; Roberts, Jason A; Oliver, Antonio; Nation, Roger L; Landersdorfer, Cornelia B.

Antimicrob Agents Chemother ; 64(7)2020 06 23.

Article in English | MEDLINE | ID: mdl-32366710

11.

Population Pharmacokinetics of Intravenous Colistin in Pediatric Patients: Implications for the Selection of Dosage Regimens.

Ooi, Mong How; Ngu, Sing Jiat; Chor, Yek Kee; Li, Jian; Landersdorfer, Cornelia B; Nation, Roger L.

Clin Infect Dis ; 69(11): 1962-1968, 2019 11 13.

Article in English | MEDLINE | ID: mdl-30722017

12.

Synergistic Meropenem-Tobramycin Combination Dosage Regimens against Clinical Hypermutable Pseudomonas aeruginosa at Simulated Epithelial Lining Fluid Concentrations in a Dynamic Biofilm Model.

Bilal, Hajira; Bergen, Phillip J; Kim, Tae Hwan; Chung, Seung Eun; Peleg, Anton Y; Oliver, Antonio; Nation, Roger L; Landersdorfer, Cornelia B.

Antimicrob Agents Chemother ; 63(11)2019 11.

Article in English | MEDLINE | ID: mdl-31427301

13.

Meropenem-Tobramycin Combination Regimens Combat Carbapenem-Resistant Pseudomonas aeruginosa in the Hollow-Fiber Infection Model Simulating Augmented Renal Clearance in Critically Ill Patients.

Yadav, Rajbharan; Bergen, Phillip J; Rogers, Kate E; Kirkpatrick, Carl M J; Wallis, Steven C; Huang, Yuling; Bulitta, Jürgen B; Paterson, David L; Lipman, Jeffrey; Nation, Roger L; Roberts, Jason A; Landersdorfer, Cornelia B.

Antimicrob Agents Chemother ; 64(1)2019 12 20.

Article in English | MEDLINE | ID: mdl-31636062

14.

Characterization of Hypermutator Pseudomonas aeruginosa Isolates from Patients with Cystic Fibrosis in Australia.

Rees, Vanessa E; Deveson Lucas, Deanna S; López-Causapé, Carla; Huang, Yuling; Kotsimbos, Tom; Bulitta, Jürgen B; Rees, Murray C; Barugahare, Adele; Peleg, Anton Y; Nation, Roger L; Oliver, Antonio; Boyce, John D; Landersdorfer, Cornelia B.

Antimicrob Agents Chemother ; 63(4)2019 04.

Article in English | MEDLINE | ID: mdl-30745381

15.

Conclusion.

Nation, Roger L.

Adv Exp Med Biol ; 1145: 363-364, 2019.

Article in English | MEDLINE | ID: mdl-31364087

16.

Clinical Pharmacokinetics, Pharmacodynamics and Toxicodynamics of Polymyxins: Implications for Therapeutic Use.

Nation, Roger L; Forrest, Alan.

Adv Exp Med Biol ; 1145: 219-249, 2019.

Article in English | MEDLINE | ID: mdl-31364081

17.

Labelling Conventions and Product Package Insert of Parenteral Polymyxins: Factors Causing Potential Medication Errors and Impeding Optimal Clinical Use.

Li, Jian; Coulthard, Kingsley; Nation, Roger L.

Adv Exp Med Biol ; 1145: 133-141, 2019.

Article in English | MEDLINE | ID: mdl-31364076

18.

Mechanisms of Polymyxin-Induced Nephrotoxicity.

Azad, Mohammad A K; Nation, Roger L; Velkov, Tony; Li, Jian.

Adv Exp Med Biol ; 1145: 305-319, 2019.

Article in English | MEDLINE | ID: mdl-31364084

19.

Personalizing Polymyxin B Dosing Using an Adaptive Feedback Control Algorithm.

Lakota, Elizabeth A; Landersdorfer, Cornelia B; Nation, Roger L; Li, Jian; Kaye, Keith S; Rao, Gauri G; Forrest, Alan.

Antimicrob Agents Chemother ; 62(7)2018 07.

Article in English | MEDLINE | ID: mdl-29760144

20.

Correction for Antachopoulos et al., "Population Pharmacokinetics and Outcomes of Critically Ill Pediatric Patients Treated with Intravenous Colistin at Higher than Recommended Doses".