Search | Virtual Health Library

1.

IL-1ß⁺ macrophages fuel pathogenic inflammation in pancreatic cancer.

Caronni, Nicoletta; La Terza, Federica; Vittoria, Francesco M; Barbiera, Giulia; Mezzanzanica, Luca; Cuzzola, Vincenzo; Barresi, Simona; Pellegatta, Marta; Canevazzi, Paolo; Dunsmore, Garett; Leonardi, Carlo; Montaldo, Elisa; Lusito, Eleonora; Dugnani, Erica; Citro, Antonio; Ng, Melissa S F; Schiavo Lena, Marco; Drago, Denise; Andolfo, Annapaola; Brugiapaglia, Silvia; Scagliotti, Alessandro; Mortellaro, Alessandra; Corbo, Vincenzo; Liu, Zhaoyuan; Mondino, Anna; Dellabona, Paolo; Piemonti, Lorenzo; Taveggia, Carla; Doglioni, Claudio; Cappello, Paola; Novelli, Francesco; Iannacone, Matteo; Ng, Lai Guan; Ginhoux, Florent; Crippa, Stefano; Falconi, Massimo; Bonini, Chiara; Naldini, Luigi; Genua, Marco; Ostuni, Renato.

Nature ; 623(7986): 415-422, 2023 Nov.

Article in English | MEDLINE | ID: mdl-37914939

2.

A neuroligin-2-YAP axis regulates progression of pancreatic intraepithelial neoplasia.

Middonti, Emanuele; Astanina, Elena; Vallariello, Edoardo; Hoza, Roxana Maria; Metovic, Jasna; Spadi, Rosella; Cristiano, Carmen; Papotti, Mauro; Allavena, Paola; Novelli, Francesco; Parab, Sushant; Cappello, Paola; Scarpa, Aldo; Lawlor, Rita; Di Maio, Massimo; Arese, Marco; Bussolino, Federico.

EMBO Rep ; 25(4): 1886-1908, 2024 Apr.

Article in English | MEDLINE | ID: mdl-38413734

3.

IL17A critically shapes the transcriptional program of fibroblasts in pancreatic cancer and switches on their protumorigenic functions.

Mucciolo, Gianluca; Curcio, Claudia; Roux, Cecilia; Li, Wanda Y; Capello, Michela; Curto, Roberta; Chiarle, Roberto; Giordano, Daniele; Satolli, Maria Antonietta; Lawlor, Rita; Scarpa, Aldo; Lukac, Pavol; Stakheev, Dmitry; Provero, Paolo; Vannucci, Luca; Mak, Tak W; Novelli, Francesco; Cappello, Paola.

Proc Natl Acad Sci U S A ; 118(6)2021 02 09.

Article in English | MEDLINE | ID: mdl-33526692

4.

Lysosomal lipid switch sensitises to nutrient deprivation and mTOR targeting in pancreatic cancer.

De Santis, Maria Chiara; Gozzelino, Luca; Margaria, Jean Piero; Costamagna, Andrea; Ratto, Edoardo; Gulluni, Federico; Di Gregorio, Enza; Mina, Erica; Lorito, Nicla; Bacci, Marina; Lattanzio, Rossano; Sala, Gianluca; Cappello, Paola; Novelli, Francesco; Giovannetti, Elisa; Vicentini, Caterina; Andreani, Silvia; Delfino, Pietro; Corbo, Vincenzo; Scarpa, Aldo; Porporato, Paolo Ettore; Morandi, Andrea; Hirsch, Emilio; Martini, Miriam.

Gut ; 72(2): 360-371, 2023 02.

Article in English | MEDLINE | ID: mdl-35623884

5.

Docking Protein p130Cas Regulates Acinar to Ductal Metaplasia During Pancreatic Adenocarcinoma Development and Pancreatitis.

Costamagna, Andrea; Natalini, Dora; Camacho Leal, Maria Del Pilar; Simoni, Matilde; Gozzelino, Luca; Cappello, Paola; Novelli, Francesco; Ambrogio, Chiara; Defilippi, Paola; Turco, Emilia; Giovannetti, Elisa; Hirsch, Emilio; Cabodi, Sara; Martini, Miriam.

Gastroenterology ; 162(4): 1242-1255.e11, 2022 04.

Article in English | MEDLINE | ID: mdl-34922945

6.

The Glycolytic Pathway as a Target for Novel Onco-Immunology Therapies in Pancreatic Cancer.

Curcio, Claudia; Brugiapaglia, Silvia; Bulfamante, Sara; Follia, Laura; Cappello, Paola; Novelli, Francesco.

Molecules ; 26(6)2021 Mar 15.

Article in English | MEDLINE | ID: mdl-33804240

7.

Computational modeling of the immune response in multiple sclerosis using epimod framework.

Pernice, Simone; Follia, Laura; Maglione, Alessandro; Pennisi, Marzio; Pappalardo, Francesco; Novelli, Francesco; Clerico, Marinella; Beccuti, Marco; Cordero, Francesca; Rolla, Simona.

BMC Bioinformatics ; 21(Suppl 17): 550, 2020 Dec 14.

Article in English | MEDLINE | ID: mdl-33308135

8.

Proteomics-Based Evidence for a Pro-Oncogenic Role of ESRP1 in Human Colorectal Cancer Cells.

Ala, Ugo; Manco, Marta; Mandili, Giorgia; Tolosano, Emanuela; Novelli, Francesco; Provero, Paolo; Altruda, Fiorella; Fagoonee, Sharmila.

Int J Mol Sci ; 21(2)2020 Jan 16.

Article in English | MEDLINE | ID: mdl-31963158

9.

Stromal protein ßig-h3 reprogrammes tumour microenvironment in pancreatic cancer.

Goehrig, Delphine; Nigri, Jérémy; Samain, Rémi; Wu, Zhichong; Cappello, Paola; Gabiane, Gaëlle; Zhang, Xinyi; Zhao, Yajie; Kim, In-San; Chanal, Marie; Curto, Roberta; Hervieu, Valerie; de La Fouchardière, Christelle; Novelli, Francesco; Milani, Pascale; Tomasini, Richard; Bousquet, Corinne; Bertolino, Philippe; Hennino, Ana.

Gut ; 68(4): 693-707, 2019 04.

Article in English | MEDLINE | ID: mdl-30415234

10.

Phosphoinositide 3-Kinase Gamma Inhibition Protects From Anthracycline Cardiotoxicity and Reduces Tumor Growth.

Li, Mingchuan; Sala, Valentina; De Santis, Maria Chiara; Cimino, James; Cappello, Paola; Pianca, Nicola; Di Bona, Anna; Margaria, Jean Piero; Martini, Miriam; Lazzarini, Edoardo; Pirozzi, Flora; Rossi, Luca; Franco, Irene; Bornbaum, Julia; Heger, Jacqueline; Rohrbach, Susanne; Perino, Alessia; Tocchetti, Carlo G; Lima, Braulio H F; Teixeira, Mauro M; Porporato, Paolo E; Schulz, Rainer; Angelini, Annalisa; Sandri, Marco; Ameri, Pietro; Sciarretta, Sebastiano; Lima-Júnior, Roberto César P; Mongillo, Marco; Zaglia, Tania; Morello, Fulvio; Novelli, Francesco; Hirsch, Emilio; Ghigo, Alessandra.

Circulation ; 138(7): 696-711, 2018 08 14.

Article in English | MEDLINE | ID: mdl-29348263

11.

The advanced glycation end-product N^Ïµ -carboxymethyllysine promotes progression of pancreatic cancer: implications for diabetes-associated risk and its prevention.

Menini, Stefano; Iacobini, Carla; de Latouliere, Luisa; Manni, Isabella; Ionta, Vittoria; Blasetti Fantauzzi, Claudia; Pesce, Carlo; Cappello, Paola; Novelli, Francesco; Piaggio, Giulia; Pugliese, Giuseppe.

J Pathol ; 245(2): 197-208, 2018 06.

Article in English | MEDLINE | ID: mdl-29533466

12.

Beta-2-glycoprotein-1 and alpha-1-antitrypsin as urinary markers of renal cancer in von Hippel-Lindau patients.

Mandili, Giorgia; Notarpietro, Agata; Khadjavi, Amina; Allasia, Marco; Battaglia, Antonino; Lucatello, Barbara; Frea, Bruno; Turrini, Francesco; Novelli, Francesco; Giribaldi, Giuliana; Destefanis, Paolo.

Biomarkers ; 23(2): 123-130, 2018 Mar.

Article in English | MEDLINE | ID: mdl-28004973

13.

The balance between IL-17 and IL-22 produced by liver-infiltrating T-helper cells critically controls NASH development in mice.

Rolla, Simona; Alchera, Elisa; Imarisio, Chiara; Bardina, Valentina; Valente, Guido; Cappello, Paola; Mombello, Cristina; Follenzi, Antonia; Novelli, Francesco; Carini, Rita.

Clin Sci (Lond) ; 130(3): 193-203, 2016 Feb.

Article in English | MEDLINE | ID: mdl-26558403

14.

Intra-tumoral IFN-Î³-producing Th22 cells correlate with TNM staging and the worst outcomes in pancreatic cancer.

Niccolai, Elena; Taddei, Antonio; Ricci, Federica; Rolla, Simona; D'Elios, Mario Milco; Benagiano, Marisa; Bechi, Paolo; Bencini, Lapo; Ringressi, Maria Novella; Pini, Alessandro; Castiglione, Francesca; Giordano, Daniele; Satolli, Maria Antonietta; Coratti, Andrea; Cianchi, Fabio; Bani, Daniele; Prisco, Domenico; Novelli, Francesco; Amedei, Amedeo.

Clin Sci (Lond) ; 130(4): 247-58, 2016 Feb.

Article in English | MEDLINE | ID: mdl-26590104

15.

Reduced cellular Ca(2+) availability enhances TDP-43 cleavage by apoptotic caspases.

De Marco, Giovanni; Lomartire, Annarosa; Mandili, Giorgia; Lupino, Elisa; Buccinnà, Barbara; Ramondetti, Cristina; Moglia, Cristina; Novelli, Francesco; Piccinini, Marco; Mostert, Michael; Rinaudo, Maria Teresa; Chiò, Adriano; Calvo, Andrea.

Biochim Biophys Acta ; 1843(4): 725-34, 2014 Apr.

Article in English | MEDLINE | ID: mdl-24440855

16.

Mouse hepatocytes and LSEC proteome reveal novel mechanisms of ischemia/reperfusion damage and protection by A2aR stimulation.

Mandili, Giorgia; Alchera, Elisa; Merlin, Simone; Imarisio, Chiara; Chandrashekar, Bangalore R; Riganti, Chiara; Bianchi, Alberto; Novelli, Francesco; Follenzi, Antonia; Carini, Rita.

J Hepatol ; 62(3): 573-80, 2015 Mar.

Article in English | MEDLINE | ID: mdl-25315650

17.

Acute-phase protein hemopexin is a negative regulator of Th17 response and experimental autoimmune encephalomyelitis development.

Rolla, Simona; Ingoglia, Giada; Bardina, Valentina; Silengo, Lorenzo; Altruda, Fiorella; Novelli, Francesco; Tolosano, Emanuela.

J Immunol ; 191(11): 5451-9, 2013 Dec 01.

Article in English | MEDLINE | ID: mdl-24154625

18.

Cancer: natural-born killers unleashed.

Hirsch, Emilio; Novelli, Francesco.

Nature ; 510(7505): 342-3, 2014 Jun 19.

Article in English | MEDLINE | ID: mdl-24919150

19.

Vaccination with ENO1 DNA prolongs survival of genetically engineered mice with pancreatic cancer.

Cappello, Paola; Rolla, Simona; Chiarle, Roberto; Principe, Moitza; Cavallo, Federica; Perconti, Giovanni; Feo, Salvatore; Giovarelli, Mirella; Novelli, Francesco.

Gastroenterology ; 144(5): 1098-106, 2013 May.

Article in English | MEDLINE | ID: mdl-23333712

20.

Chronic hypoxia reprograms human immature dendritic cells by inducing a proinflammatory phenotype and TREM-1 expression.

Pierobon, Daniele; Bosco, Maria Carla; Blengio, Fabiola; Raggi, Federica; Eva, Alessandra; Filippi, Miriam; Musso, Tiziana; Novelli, Francesco; Cappello, Paola; Varesio, Luigi; Giovarelli, Mirella.

Eur J Immunol ; 43(4): 949-66, 2013 Apr.

Article in English | MEDLINE | ID: mdl-23436478

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