Search | Virtual Health Library

1.

Unraveling the diversity and functions of tissue-resident plasma cells.

Tellier, Julie; Tarasova, Ilariya; Nie, Junli; Smillie, Christopher S; Fedele, Pasquale L; Cao, Wang H J; Groom, Joanna R; Belz, Gabrielle T; Bhattacharya, Deepta; Smyth, Gordon K; Nutt, Stephen L.

Nat Immunol ; 25(2): 330-342, 2024 Feb.

Article in English | MEDLINE | ID: mdl-38172260

2.

IKAROS and AIOLOS directly regulate AP-1 transcriptional complexes and are essential for NK cell development.

Goh, Wilford; Sudholz, Harrison; Foroutan, Momeneh; Scheer, Sebastian; Pfefferle, Aline; Delconte, Rebecca B; Meng, Xiangpeng; Shen, Zihan; Hennessey, Robert; Kong, Isabella Y; Schuster, Iona S; Andoniou, Christopher E; Davis, Melissa J; Hediyeh-Zadeh, Soroor; Souza-Fonseca-Guimaraes, Fernando; Parish, Ian A; Beavis, Paul; Thiele, Daniel; Chopin, Michael; Degli-Esposti, Mariapia A; Cursons, Joe; Kallies, Axel; Rautela, Jai; Nutt, Stephen L; Huntington, Nicholas D.

Nat Immunol ; 25(2): 240-255, 2024 Feb.

Article in English | MEDLINE | ID: mdl-38182668

3.

Liver Immune Profiling Reveals Pathogenesis and Therapeutics for Biliary Atresia.

Wang, Jun; Xu, Yanhui; Chen, Zhanghua; Liang, Jiankun; Lin, Zefeng; Liang, Huiying; Xu, Yiping; Wu, Qi; Guo, Xuanjie; Nie, Junli; Lu, Bingtai; Huang, Bing; Xian, Huifang; Wang, Xiaohui; Wu, Qiang; Zeng, Jixiao; Chai, Chengwei; Zhang, Meixue; Lin, Yuzhen; Zhang, Li; Zhao, Shanmeizi; Tong, Yanlu; Zeng, Liang; Gu, Xiaoqiong; Chen, Zhuang-Gui; Yi, Shuhong; Zhang, Tong; Delfouneso, David; Zhang, Yan; Nutt, Stephen L; Lew, Andrew M; Lu, Liwei; Bai, Fan; Xia, Huimin; Wen, Zhe; Zhang, Yuxia.

Cell ; 183(7): 1867-1883.e26, 2020 12 23.

Article in English | MEDLINE | ID: mdl-33248023

4.

The cis-Regulatory Atlas of the Mouse Immune System.

Yoshida, Hideyuki; Lareau, Caleb A; Ramirez, Ricardo N; Rose, Samuel A; Maier, Barbara; Wroblewska, Aleksandra; Desland, Fiona; Chudnovskiy, Aleksey; Mortha, Arthur; Dominguez, Claudia; Tellier, Julie; Kim, Edy; Dwyer, Dan; Shinton, Susan; Nabekura, Tsukasa; Qi, YiLin; Yu, Bingfei; Robinette, Michelle; Kim, Ki-Wook; Wagers, Amy; Rhoads, Andrew; Nutt, Stephen L; Brown, Brian D; Mostafavi, Sara; Buenrostro, Jason D; Benoist, Christophe.

Cell ; 176(4): 897-912.e20, 2019 02 07.

Article in English | MEDLINE | ID: mdl-30686579

5.

Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanoma.

Jacquelot, Nicolas; Seillet, Cyril; Wang, Minyu; Pizzolla, Angela; Liao, Yang; Hediyeh-Zadeh, Soroor; Grisaru-Tal, Sharon; Louis, Cynthia; Huang, Qiutong; Schreuder, Jaring; Souza-Fonseca-Guimaraes, Fernando; de Graaf, Carolyn A; Thia, Kevin; Macdonald, Sean; Camilleri, Mary; Luong, Kylie; Zhang, Shengbo; Chopin, Michael; Molden-Hauer, Tristan; Nutt, Stephen L; Umansky, Viktor; Ciric, Bogoljub; Groom, Joanna R; Foster, Paul S; Hansbro, Philip M; McKenzie, Andrew N J; Gray, Daniel H D; Behren, Andreas; Cebon, Jonathan; Vivier, Eric; Wicks, Ian P; Trapani, Joseph A; Munitz, Ariel; Davis, Melissa J; Shi, Wei; Neeson, Paul J; Belz, Gabrielle T.

Nat Immunol ; 22(7): 851-864, 2021 07.

Article in English | MEDLINE | ID: mdl-34099918

6.

A new lymphoid-primed progenitor marked by Dach1 downregulation identified with single cell multi-omics.

Amann-Zalcenstein, Daniela; Tian, Luyi; Schreuder, Jaring; Tomei, Sara; Lin, Dawn S; Fairfax, Kirsten A; Bolden, Jessica E; McKenzie, Mark D; Jarratt, Andrew; Hilton, Adrienne; Jackson, Jacob T; Di Rago, Ladina; McCormack, Matthew P; de Graaf, Carolyn A; Stonehouse, Olivia; Taoudi, Samir; Alexander, Warren S; Nutt, Stephen L; Ritchie, Matthew E; Ng, Ashley P; Naik, Shalin H.

Nat Immunol ; 21(12): 1574-1584, 2020 12.

Article in English | MEDLINE | ID: mdl-33077975

7.

Selective deployment of transcription factor paralogs with submaximal strength facilitates gene regulation in the immune system.

Bruno, Ludovica; Ramlall, Vijendra; Studer, Romain A; Sauer, Stephan; Bradley, David; Dharmalingam, Gopuraja; Carroll, Thomas; Ghoneim, Mohamed; Chopin, Michaël; Nutt, Stephen L; Elderkin, Sarah; Rueda, David S; Fisher, Amanda G; Siggers, Trevor; Beltrao, Pedro; Merkenschlager, Matthias.

Nat Immunol ; 20(10): 1372-1380, 2019 10.

Article in English | MEDLINE | ID: mdl-31451789

8.

Transcription-factor-mediated supervision of global genome architecture maintains B cell identity.

Johanson, Timothy M; Lun, Aaron T L; Coughlan, Hannah D; Tan, Tania; Smyth, Gordon K; Nutt, Stephen L; Allan, Rhys S.

Nat Immunol ; 19(11): 1257-1264, 2018 11.

Article in English | MEDLINE | ID: mdl-30323344

9.

The secret to longevity, plasma cell style.

Tellier, Julie; Nutt, Stephen L.

Nat Immunol ; 23(11): 1507-1508, 2022 11.

Article in English | MEDLINE | ID: mdl-36316478

10.

Transcriptional Networks Driving Dendritic Cell Differentiation and Function.

Nutt, Stephen L; Chopin, Michaël.

Immunity ; 52(6): 942-956, 2020 06 16.

Article in English | MEDLINE | ID: mdl-32553180

11.

Blimp-1 controls plasma cell function through the regulation of immunoglobulin secretion and the unfolded protein response.

Tellier, Julie; Shi, Wei; Minnich, Martina; Liao, Yang; Crawford, Simon; Smyth, Gordon K; Kallies, Axel; Busslinger, Meinrad; Nutt, Stephen L.

Nat Immunol ; 17(3): 323-30, 2016 Mar.

Article in English | MEDLINE | ID: mdl-26779600

12.

Multifunctional role of the transcription factor Blimp-1 in coordinating plasma cell differentiation.

Minnich, Martina; Tagoh, Hiromi; Bönelt, Peter; Axelsson, Elin; Fischer, Maria; Cebolla, Beatriz; Tarakhovsky, Alexander; Nutt, Stephen L; Jaritz, Markus; Busslinger, Meinrad.

Nat Immunol ; 17(3): 331-43, 2016 Mar.

Article in English | MEDLINE | ID: mdl-26779602

13.

A molecular threshold for effector CD8(+) T cell differentiation controlled by transcription factors Blimp-1 and T-bet.

Xin, Annie; Masson, Frederick; Liao, Yang; Preston, Simon; Guan, Tianxia; Gloury, Renee; Olshansky, Moshe; Lin, Jian-Xin; Li, Peng; Speed, Terence P; Smyth, Gordon K; Ernst, Matthias; Leonard, Warren J; Pellegrini, Marc; Kaech, Susan M; Nutt, Stephen L; Shi, Wei; Belz, Gabrielle T; Kallies, Axel.

Nat Immunol ; 17(4): 422-32, 2016 Apr.

Article in English | MEDLINE | ID: mdl-26950239

14.

A Regulatory Circuit Controlling the Dynamics of NFκB cRel Transitions B Cells from Proliferation to Plasma Cell Differentiation.

Roy, Koushik; Mitchell, Simon; Liu, Yi; Ohta, Sho; Lin, Yu-Sheng; Metzig, Marie Oliver; Nutt, Stephen L; Hoffmann, Alexander.

Immunity ; 50(3): 616-628.e6, 2019 03 19.

Article in English | MEDLINE | ID: mdl-30850343

15.

Transcription Factor PU.1 Promotes Conventional Dendritic Cell Identity and Function via Induction of Transcriptional Regulator DC-SCRIPT.

Chopin, Michaël; Lun, Aaron T; Zhan, Yifan; Schreuder, Jaring; Coughlan, Hannah; D'Amico, Angela; Mielke, Lisa A; Almeida, Francisca F; Kueh, Andrew J; Dickins, Ross A; Belz, Gabrielle T; Naik, Shalin H; Lew, Andrew M; Bouillet, Phillipe; Herold, Marco J; Smyth, Gordon K; Corcoran, Lynn M; Nutt, Stephen L.

Immunity ; 50(1): 77-90.e5, 2019 01 15.

Article in English | MEDLINE | ID: mdl-30611612

16.

MYB orchestrates T cell exhaustion and response to checkpoint inhibition.

Tsui, Carlson; Kretschmer, Lorenz; Rapelius, Svenja; Gabriel, Sarah S; Chisanga, David; Knöpper, Konrad; Utzschneider, Daniel T; Nüssing, Simone; Liao, Yang; Mason, Teisha; Torres, Santiago Valle; Wilcox, Stephen A; Kanev, Krystian; Jarosch, Sebastian; Leube, Justin; Nutt, Stephen L; Zehn, Dietmar; Parish, Ian A; Kastenmüller, Wolfgang; Shi, Wei; Buchholz, Veit R; Kallies, Axel.

Nature ; 609(7926): 354-360, 2022 09.

Article in English | MEDLINE | ID: mdl-35978192

17.

Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells.

Shi, Wei; Liao, Yang; Willis, Simon N; Taubenheim, Nadine; Inouye, Michael; Tarlinton, David M; Smyth, Gordon K; Hodgkin, Philip D; Nutt, Stephen L; Corcoran, Lynn M.

Nat Immunol ; 16(6): 663-73, 2015 Jun.

Article in English | MEDLINE | ID: mdl-25894659

18.

The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue-resident regulatory T cells.

Vasanthakumar, Ajithkumar; Moro, Kazuyo; Xin, Annie; Liao, Yang; Gloury, Renee; Kawamoto, Shimpei; Fagarasan, Sidonia; Mielke, Lisa A; Afshar-Sterle, Shoukat; Masters, Seth L; Nakae, Susumu; Saito, Hirohisa; Wentworth, John M; Li, Peng; Liao, Wei; Leonard, Warren J; Smyth, Gordon K; Shi, Wei; Nutt, Stephen L; Koyasu, Shigeo; Kallies, Axel.

Nat Immunol ; 16(3): 276-85, 2015 Mar.

Article in English | MEDLINE | ID: mdl-25599561

19.

Transcription Factor Theft-PU.1 Caught Red-Handed.

Kallies, Axel; Nutt, Stephen L.

Immunity ; 48(6): 1063-1065, 2018 06 19.

Article in English | MEDLINE | ID: mdl-29924967

20.

Effector Regulatory T Cell Differentiation and Immune Homeostasis Depend on the Transcription Factor Myb.

Dias, Sheila; D'Amico, Angela; Cretney, Erika; Liao, Yang; Tellier, Julie; Bruggeman, Christine; Almeida, Francisca F; Leahy, Jamie; Belz, Gabrielle T; Smyth, Gordon K; Shi, Wei; Nutt, Stephen L.

Immunity ; 46(1): 78-91, 2017 01 17.

Article in English | MEDLINE | ID: mdl-28099866

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