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1.
Afr J Med Med Sci ; 43(3): 219-23, 2014 Sep.
Article in English | MEDLINE | ID: mdl-26223139

ABSTRACT

BACKGROUND: Laparoscopy is now readily being deployed for abdominal surgeries in our centre, thanks to the surgeons' interest and the desire to follow best practice as obtained in other climes. General anaesthesia (GA) with intermittent positive pressure ventilation is usually the preferred mode of anaesthesia for this procedure. There are reports of laparoscopic surgery of abdomen performed under spinal and or epidural anaesthetic techniques. METHODS: With Intra-Abdominal Pressure (IAP) from CO2 insufflations limited to 10-12 mmHg, Laparoscopic Appendicectomy (LA) was performed under Combined Spinal Epidural (CSE) for ten consenting ASA 1 and II patients with mean age 23.6 years and BMI of 24.9 kg/m2 in University College Hospital Ibadan, Nigeria. Intra-operative events and ease of operation were studied; systemic drugs were administered if patients complained of pain and discomfort, and G.A if regional techniques and sedation failed. RESULTS: Eight(8) patients had the procedure completed under spinal anaesthesia supplemented with sedation, two (2) patients whose block went as high as T4 had no need of sedation. There were operative difficulties in four patients out of which 2 had sedations and the surgeons could continue operating. We converted to GA in two (2) patients when regional techniques and sedation failed. CONCLUSION: We concluded that with proper selection of patients and limiting IAP to 10-12 mmHg, LA can be safely performed with spinal anaesthesia with some supplementation.


Subject(s)
Anesthetics/administration & dosage , Appendectomy/methods , Hypnotics and Sedatives/administration & dosage , Laparoscopy/methods , Abdomen/physiopathology , Abdomen/surgery , Adult , Anesthesia, Spinal/methods , Female , Humans , Male , Monitoring, Intraoperative , Nigeria , Patient Selection , Treatment Outcome
2.
Afr J Med Med Sci ; 41(4): 429-36, 2012 Dec.
Article in English | MEDLINE | ID: mdl-23672109

ABSTRACT

OBJECTIVE: The study evaluated the morphine sparing effect of intravenous Paracetamol and the incidence of side effects in the recovery room following lower abdominal gynaecological surgery. METHOD: Fifty six, ASA I and II patients undergoing lower abdominal gynaecological surgery were randomized into two groups, which were either given (A) intravenous (I.V) Paracetamol 1g diluted to 20 mls with normal saline or (B) I.V normal saline 20 mls at the beginning of the skin closure. In the re covery room pain intensity was evaluated and the time of first request for analgesic was noted. Intravenous morphine 2mg bolus was titrated to . Pain relief was evaluated at rest and on movement until pain score at rest Numerical rating score (NRS) < or = was achieved. Total dose of morphine was noted, morphine side effects, adequacy of analgesia and patient's satisfaction were assessed. RESULTS: The mean time of first analgesic request was prolonged significantly in Group A 40.9 +/-18.9 minutes vs. 11.4 +/- 5.5 minutes in Group B ( P = 0.00), with significant difference in morphine consumption 7.1 +/- 1.6 vs. 12.2 +/- 2.1 (P = 0.01) respectively. Morphine related side effects were higher in placebo group (33.3%) compared with (11.1%) in paracetamol group. More patients in the paracetamol group compared with the placebo group felt pain relief was adequate (66.7% vs 44.4%) and also more patients were satisfied with the regimen in paracetamol group compared with placebo group (96% vs 29.6%). CONCLUSION: Intravenous Paracetamol improved analgesia and reduced the amount of morphine consumption in the immediate postoperative period with reduced opioid side effects and better patient satisfaction.


Subject(s)
Acetaminophen/therapeutic use , Analgesics/therapeutic use , Gynecologic Surgical Procedures/adverse effects , Morphine/therapeutic use , Pain, Postoperative/drug therapy , Adolescent , Adult , Aged , Drug Therapy, Combination/methods , Female , Humans , Hysterectomy/adverse effects , Infusions, Intravenous , Middle Aged , Pain Measurement , Pain, Postoperative/etiology , Uterine Myomectomy/adverse effects , Young Adult
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