Search | Virtual Health Library

1.

ZBTB2 links p53 deficiency to HIF-1-mediated hypoxia signaling to promote cancer aggressiveness.

Koyasu, Sho; Horita, Shoichiro; Saito, Keisuke; Kobayashi, Minoru; Ishikita, Hiroshi; Chow, Christalle Ct; Kambe, Gouki; Nishikawa, Shigeto; Menju, Toshi; Morinibu, Akiyo; Okochi, Yasushi; Tabuchi, Yoshiaki; Onodera, Yasuhito; Takeda, Norihiko; Date, Hiroshi; Semenza, Gregg L; Hammond, Ester M; Harada, Hiroshi.

EMBO Rep ; 24(1): e54042, 2023 01 09.

Article in English | MEDLINE | ID: mdl-36341521

2.

LRRK2 is involved in the chemotaxis of neutrophils and differentiated HL-60 cells, and the inhibition of LRRK2 kinase activity increases fMLP-induced chemotactic activity.

Mazaki, Yuichi; Handa, Haruka; Fumoto, Yoshizuki; Horinouchi, Takahiro; Onodera, Yasuhito.

Cell Commun Signal ; 21(1): 300, 2023 10 30.

Article in English | MEDLINE | ID: mdl-37904222

3.

The oxidized-LDL/LOX-1 axis in tumor endothelial cells enhances metastasis by recruiting neutrophils and cancer cells.

Tsumita, Takuya; Maishi, Nako; Annan, Dorcas Akuba-Muhyia; Towfik, Mohammad Alam; Matsuda, Aya; Onodera, Yasuhito; Nam, Jin-Min; Hida, Yasuhiro; Hida, Kyoko.

Int J Cancer ; 151(6): 944-956, 2022 09 15.

Article in English | MEDLINE | ID: mdl-35608341

4.

The oral bacterium Streptococcus mutans promotes tumor metastasis by inducing vascular inflammation.

Yu, Li; Maishi, Nako; Akahori, Erika; Hasebe, Akira; Takeda, Ryo; Matsuda, Aya Yanagawa; Hida, Yasuhiro; Nam, Jin-Min; Onodera, Yasuhito; Kitagawa, Yoshimasa; Hida, Kyoko.

Cancer Sci ; 113(11): 3980-3994, 2022 Nov.

Article in English | MEDLINE | ID: mdl-35997541

5.

ARF6 and AMAP1 are major targets of KRAS and TP53 mutations to promote invasion, PD-L1 dynamics, and immune evasion of pancreatic cancer.

Hashimoto, Shigeru; Furukawa, Shotaro; Hashimoto, Ari; Tsutaho, Akio; Fukao, Akira; Sakamura, Yurika; Parajuli, Gyanu; Onodera, Yasuhito; Otsuka, Yutaro; Handa, Haruka; Oikawa, Tsukasa; Hata, Soichiro; Nishikawa, Yoshihiro; Mizukami, Yusuke; Kodama, Yuzo; Murakami, Masaaki; Fujiwara, Toshinobu; Hirano, Satoshi; Sabe, Hisataka.

Proc Natl Acad Sci U S A ; 116(35): 17450-17459, 2019 08 27.

Article in English | MEDLINE | ID: mdl-31399545

6.

Strategies for all-at-once and stepwise selection of cells with multiple genetic manipulations.

Horikawa, Mei; Sabe, Hisataka; Onodera, Yasuhito.

Biochem Biophys Res Commun ; 582: 93-99, 2021 12 10.

Article in English | MEDLINE | ID: mdl-34695756

7.

Mitofusin 2 is involved in chemotaxis of neutrophil-like differentiated HL-60â¯cells.

Mazaki, Yuichi; Takada, Shingo; Nio-Kobayashi, Junko; Maekawa, Satoshi; Higashi, Tsunehito; Onodera, Yasuhito; Sabe, Hisataka.

Biochem Biophys Res Commun ; 513(3): 708-713, 2019 06 04.

Article in English | MEDLINE | ID: mdl-30987827

8.

ARF1 recruits RAC1 to leading edge in neutrophil chemotaxis.

Mazaki, Yuichi; Onodera, Yasuhito; Higashi, Tsunehito; Horinouchi, Takahiro; Oikawa, Tsukasa; Sabe, Hisataka.

Cell Commun Signal ; 15(1): 36, 2017 10 02.

Article in English | MEDLINE | ID: mdl-28969640

9.

High expression of EPB41L5, an integral component of the Arf6-driven mesenchymal program, correlates with poor prognosis of squamous cell carcinoma of the tongue.

Otsuka, Yutaro; Sato, Hiroki; Oikawa, Tsukasa; Onodera, Yasuhito; Nam, Jin-Min; Hashimoto, Ari; Fukunaga, Kiyoshi; Hatanaka, Kanako C; Hatanaka, Yutaka; Matsuno, Yoshihiro; Fukuda, Satoshi; Sabe, Hisataka.

Cell Commun Signal ; 14(1): 28, 2016 11 21.

Article in English | MEDLINE | ID: mdl-27871329

10.

In vivo CRISPR screening directly targeting testicular cells.

Noguchi, Yuki; Onodera, Yasuhito; Miyamoto, Tatsuo; Maruoka, Masahiro; Kosako, Hidetaka; Suzuki, Jun.

Cell Genom ; 4(3): 100510, 2024 Mar 13.

Article in English | MEDLINE | ID: mdl-38447574

11.

The lipid-binding D4 domain of perfringolysin O facilitates the active loading of exogenous cargo into extracellular vesicles.

Opadele, Abayomi Emmanuel; Nishioka, Soichiro; Wu, Ping-Hsiu; Le, Quynh-Thu; Shirato, Hiroki; Nam, Jin-Min; Onodera, Yasuhito.

FEBS Lett ; 598(4): 446-456, 2024 Feb.

Article in English | MEDLINE | ID: mdl-38339784

12.

ß1-Integrin via NF-κB signaling is essential for acquisition of invasiveness in a model of radiation treated in situ breast cancer.

Nam, Jin-Min; Ahmed, Kazi M; Costes, Sylvain; Zhang, Hui; Onodera, Yasuhito; Olshen, Adam B; Hatanaka, Kanako C; Kinoshita, Rumiko; Ishikawa, Masayori; Sabe, Hisataka; Shirato, Hiroki; Park, Catherine C.

Breast Cancer Res ; 15(4): R60, 2013.

Article in English | MEDLINE | ID: mdl-23883667

13.

ArfGAP family proteins in cell adhesion, migration and tumor invasion.

Sabe, Hisataka; Onodera, Yasuhito; Mazaki, Yuichi; Hashimoto, Shigeru.

Curr Opin Cell Biol ; 18(5): 558-64, 2006 Oct.

Article in English | MEDLINE | ID: mdl-16904307

14.

Angiogenic inhibitor pre-administration improves the therapeutic effects of immunotherapy.

Sato, Mineyoshi; Maishi, Nako; Hida, Yasuhiro; Yanagawa-Matsuda, Aya; Alam, Mohammad Towfik; Sakakibara-Konishi, Jun; Nam, Jin-Min; Onodera, Yasuhito; Konno, Satoshi; Hida, Kyoko.

Cancer Med ; 12(8): 9760-9773, 2023 04.

Article in English | MEDLINE | ID: mdl-36808261

15.

Dual roles of AMAP1 in the transcriptional regulation and intracellular trafficking of carbonic anhydrase IX.

Horikawa, Mei; Sabe, Hisataka; Onodera, Yasuhito.

Transl Oncol ; 15(1): 101258, 2022 Jan.

Article in English | MEDLINE | ID: mdl-34742153

16.

A Consistent Protocol Reveals a Large Heterogeneity in the Biological Effectiveness of Proton and Carbon-Ion Beams for Various Sarcoma and Normal-Tissue-Derived Cell Lines.

Yagi, Masashi; Takahashi, Yutaka; Minami, Kazumasa; Matsuura, Taeko; Nam, Jin-Min; Onodera, Yasuhito; Akagi, Takashi; Maeda, Takuya; Okimoto, Tomoaki; Shirato, Hiroki; Ogawa, Kazuhiko.

Cancers (Basel) ; 14(8)2022 Apr 15.

Article in English | MEDLINE | ID: mdl-35454915

17.

Proteolysis of a histone acetyl reader, ATAD2, induces chemoresistance of cancer cells under severe hypoxia by inhibiting cell cycle progression in S phase.

Haitani, Takao; Kobayashi, Minoru; Koyasu, Sho; Akamatsu, Shusuke; Suwa, Tatsuya; Onodera, Yasuhito; Nam, Jin-Min; Nguyen, Phuong Thi Lien; Menju, Toshi; Date, Hiroshi; Ogawa, Osamu; Harada, Hiroshi.

Cancer Lett ; 528: 76-84, 2022 03 01.

Article in English | MEDLINE | ID: mdl-34973392

18.

The EGFR-GEP100-Arf6-AMAP1 signaling pathway specific to breast cancer invasion and metastasis.

Sabe, Hisataka; Hashimoto, Shigeru; Morishige, Masaki; Ogawa, Eiji; Hashimoto, Ari; Nam, Jin-Min; Miura, Koichi; Yano, Hajime; Onodera, Yasuhito.

Traffic ; 10(8): 982-93, 2009 Aug.

Article in English | MEDLINE | ID: mdl-19416474

19.

[Post-transcriptional regulation and metabolism].

Onodera, Yasuhito.

Seikagaku ; 88(3): 308-13, 2016 Jun.

Article in Japanese | MEDLINE | ID: mdl-27483948

20.

Lysosomal trafficking mediated by Arl8b and BORC promotes invasion of cancer cells that survive radiation.

Wu, Ping-Hsiu; Onodera, Yasuhito; Giaccia, Amato J; Le, Quynh-Thu; Shimizu, Shinichi; Shirato, Hiroki; Nam, Jin-Min.

Commun Biol ; 3(1): 620, 2020 10 27.

Article in English | MEDLINE | ID: mdl-33110168

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